Overview
Cincinnati Children's Research Foundation has put in place core support capabilities for both basic and clinical research. These core resources enhance access to cutting-edge technology and data analysis for a wide variety of projects. Researchers in the Research Foundation can access these shared resources by contacting the director of the core using the contact information below.
For a capsule summary of all the cores, visit our core summary page. To learn more about a particular core, visit the core's web page by clicking on the specific link below.
In addition to cores hosted at the Cincinnati Children's Research Foundation, faculty also have access to the research cores hosted at the University of Cincinnati's College of Medicine. You can learn more about UC's cores here.
- Animal Behavioral Core
The Animal Behavioral Collaborative Core facility, located in the Division of Neurology, is available to PIs at CCRF, UC and outside Principle Investigators. The core offers a variety of behavioral assays to enable the characterization of CNS dysfunction in mice or rats. Learn More »
Director: Charles V. Vorhees, PhD
Phone: 513-636-8622
- Biomedical Informatics
Creates advanced scientific discovery and management software. Provides on-going bioinformatics and biomedicial engineering training for staff and students. Provides strategic guidance related to the impact of computation systems and data on research. Learn More »
Director: John Hutton, MD
Phone: 513-636-1627
- Biostatistics Core, Center for Epidemiology and Biostatistics
Provides consultation services and ongoing support to researchers and clinicians, including developing clinical research plans, pursuit of funding, conducting research, and analyzing data. Learn More »
Director: Ardythe Morrow, PhD
Phone: 513-636-7584
- Cardiovascular Imaging Core
Based in the Division of Cardiology the
Core provides cardiac ultrasound support and cardiovascular anatomic
and physiologic expertise to any investigator with funding who is
interested in cardiac and vascular structure and function in both human
and animal studies. Learn More »
Director: Thomas R. Kimball, MD
Phone: 513-636-8270
- Cell Manipulations Laboratory
Provides controlled access clean room facility that was designed and built for the purpose of performing ex-vivo cell manipulations, including gene therapy protocols, for Phase I & II clinical trials. Learn More »
Director: Tom Leemhuis, PhD
Phone: 513-558-1553
- Cardiovascular Imaging Core Research Laboratory
- Child Policy Research Center
The Child Policy Research Center is a focal point for research, analysis and information to inform child health policy decisions Learn More »Director: Lisa Simpson, MB, BCh, MPH, FAAP
Phone: 513-636-2781
- Cincinnati Center for Clinical Research
Organizes and supports both pediatric (Phase I-IV) and adult (Phase I-III) clinical research studies for the faculty. Learn More »
Director: Michael Spigarelli, MD, PhD
Phone: 513-636-5311
- Cincinnati Center for Nutritional Research and Analysis
Collects and analyzes nutrition data from research studies. Learn More »
Director: Marcia Schmidt MS, RD, LD
Phone: 513-636-4142
- Comprehensive Mouse and Cancer Core
The Cincinnati Children's Hospital Medical Center Comprehensive Mouse and Cancer Core (supported by Cincinnati Children's) at the Division of Experimental Hematology and Cancer Biology provides animals from specific inbred mouse strains primarily used in cancer and hematopoietic research offers animal and cell irradiation services, cell transplant and hematopoietic cell harvest services, and handling of animal cancer model systems involving xenotransplant procedures. Learn More »
Director: Hartmut Geiger, PhD
Phone: 513-636-1338
- Echocardiography
Provides non-invasive ultrasound imaging in support of both animal and human research studies. Provides complete anatomical detail of the heart and makes functional assessments of cardiac geometry, pressures, systolic function and diastolic function. Director: Tom Kimball, MD
Phone: 513-636-3577
- Flow Cytometry and Cell Sorting Services
A functionally integrated core providing diverse flow cytometric applications for characterization and purification of cells from mixed cell suspensions. Provides consultation and service. Learn More »
Director: Alexandra Filipovich, MD
Phone: 513-636-8614
- Flow Cytometry
Analytical flow cytometry of cells in suspension; no sorting capability.
Director: Jose Cancelas, MD, PhD
Phone: 513-558-1324
- General Clinical Research Center (GCRC)
Provides facilities and resources for inpatient and outpatient research, including program administration, clinical services, nutrition research services, behavioral core services, biostatistical and informatics services, and laboratory services. Learn More »
Director: Jim Heubi, MD
Phone: 513-636-8046
GCRC Behavorial Core
Director: M. Douglas Ris, PhD
Phone: 513-636-8757
- Affymetrix GENECHIP" Microarray Core
Performs simultaneous analysis of expression levels of tens of thousands of genes using high density oligonucleotide microarrays, with over one million hybridization features per gene chip. Learn More »
Director: S. Steven Potter, PhD
Phone: 513-636-4850
- Health Policy and Clinical Effectiveness
Collaborates with clinical teams and health care leaders to identify, develop,implement and evaluate strategies for cost-effective, evidence-based management of childhood disease. Learn More »
Director: Uma Kotagal, MBBS, MSc
Phone: 513-636-0178
- Imaging Research Center
Provides access to state of the art MRI Research Instrumentation and diagnostic imaging technologies related to the diagnosis and treatment of diseases in children and young adults. An in-vivo microimaging laboratory is being established and will available for use in April, 2004 to develop micro and molecular imaging techniques in models of pediatric disease. Learn More »
Director: Alan Brody, MD
Phone: 513-636-7230
- Laser Capture Microdissection
Provides a pure cell population for subsequent quantitative analysis by directly extracting single cells from any tissue section. Learn More »
Director: Xiaonan Han, PhD
Phone: 513-636-7592
- Mass Spectrometry
Provides an analytical resource that focuses on the application of mass spectrometry and allied chromatographic approaches to the analysis of complex biological samples. Learn More »
Director: Kenneth D. Setchell, PhD
Phone: 513-636-4548
- Pediatric Pharmacology Research Unit
Performs pediatric drug trials and translational research studies. Learn More »
Director: Sander Vinks, PharmD, PhD, FCP
Phone: 513-636-0160
- Protein Characterization and Proteomics
Provides analysis and identification of purified proteins as well as complex protein mixtures. Also provides expertise in the planning and design of proteomics experiments. Learn More »
Director: Ken Greis, PhD
Phone: 513-558-7102
- Office of Research Compliance and Regulatory Affairs
The ORCRA helps research departments comply with all relevant regulatory organizations by providing auditing, standard practices, and institutional guidance/approval.
Director: Jeremy Corsmo, MPH, CIP
Phone: 513-636-5449
- Sequencing
Sequencing with template preparation from bacterial cultures; sequencing without template preparation; and electrophoresis. Learn More »
Director: Greg Grabowski, MD
Phone: 513-636-7290
Lab Phone: 513-636-2801
- Tissue Culture Laboratory
Establishes cell lines, immortalizes lymphoid lines, provides storage facility.
Director: Howard Saal, MD
Phone: 513-636-4474
- Transgenic and Gene Targeting Core
Specializes in embryo cryopreservation and the generation of genetically altered mice and rabbits. Learn More »
Director: Richard Lang, PhD
Phone: 513-636-2700
- Translational Research
Facilitates the development of pre-clinical and human translational trials. Learn More »
Director: Tim Cripe, MD, PhD
Phone: 513-636-4553
- Translational Research Development and Support Laboratory
Coordinates and/or performs cellular and molecular testing required to document purity, function, clonal composition, and overall safety of research preparations and samples. Learn More »
Director: Lilith Reeves
Phone: 513-636-3468
- Viral Vector Core
Provides research-grade Retroviral Lentiviral and Adeno Associated Virus Vectors. Learn More »
Director: Han van der Loo
Phone: 513-803-1066
- Veterinary Services
Provides routine and specialized husbandry, surgical support and expert consultation on regulatory issues (IACUC submissions) and animal transfers.
Director: Gary Keller, DVM
Phone: 513-636-4441
Contact Us
For more information about general research cores, contact Jeffrey Robbins, PhD, 513-636-8098.
