• We Use Team Science to Find Cures for the Most Challenging Cancers on Earth

    At Cincinnati Children’s, we make science count for kids.

    Every day, more than 1,000 doctors, nurses, scientists, researchers and staff in our Cancer and Blood Diseases Institute work as focused teams to provide the most innovative care for the most difficult cancer cases in the world.

    “We have highly recognized faculty with outstanding international reputations, but the key ingredient is team science,” says John Perentesis, MD, FAAP, director of oncology and cancer programs and co-director of the Cancer and Blood Diseases Institute. “Each of our clinical teams is embedded with basic science researchers. This close collaboration allows advances from the laboratory to reach children as quickly as possible.”

    Cincinnati Children’s launched the first personalized medicine center to use genomic science to design precise, individual treatments for children and young adults with cancer. We are developing designer drugs that hit cancer cells while sparing normal cells. We are transforming how children receive radiation therapy. And so much more.  

    “We have the largest array of new anti-cancer treatments for children of any medical center in the country. As a result, children with very complex cases are referred here from all around the world,” Perentesis says. “We are proud that our cancer program was rated No. 2 in the nation for childhood cancer care by U.S. News & World Report.”

    Why We Stand Out 

    • Our new cancer genomics-guided treatment program is one of the main reasons why so many children with high-risk or relapsed malignancies are referred here from all around the world. According to our latest research, about 50 percent of children with high-risk forms of cancer receiving genomics-guided treatment experienced dramatic tumor shrinkage compared to just 6 percent without genomic guidance.  
    • We are constructing a new Proton Therapy Center that will transform how children receive radiotherapy. This new technology will significantly improve outcomes while dramatically reducing potential long-term risks. The facility will be one of only two pediatric-focused proton therapy centers in the United States, and the only one with a fully dedicated proton research center.  
    • We are the leading national center for bone marrow transplants and related therapies.  
    • We have developed an innovative, multidisciplinary fertility preservation program that will help childhood cancer survivors become parents when they grow up. 
    • We are a leader in developing anti-cancer immune therapies, including a new program that uses engineered T-cells against relapsed leukemias. 
    • Scientists in our Brain Tumor Center recently discovered that an existing anti-depressant medication may help treat a deadly form of brain cancer. We plan to launch a clinical trial to test the medication later this year. 
    • Our research never stops.  Our faculty presented a record number of findings at this year’s annual meeting of the American Society for Clinical Oncology, and we won’t slow down until every child with cancer becomes a cancer survivor.