Helen N. Jones, PhD

Assistant Professor, UC Department of Surgery

Phone 513-636-7861

Fax 513-636-3774

Email helen.jones@cchmc.org

Regulation of placental growth and function; regulation of mechanisms of placental nutrient transfer and consequences for fetal growth

Visit the Jones Lab.

PhD: Rowett Research Institute, University of Aberdeen, Scotland, 2005.

BS: University of St. Andrews, Scotland, 2000.

Wang K, Dong HQ, Zhao ZL, Li YY, Li C, Jones HN, Shi DL,Zhang XZ. Novel Vesicles Self-Assembled from Amphiphilic Star-Armed PEG-Polypeptide Hybrid Copolymers for Drug Delivery. Macromolecular Bioscience 2011;11:65-71.

Jones HN, Powell TL, Jansson T. Differential regulation of placental amino acid transport mechanisms by Adiponectin. Diabetes. 2010;59(5):1161-70.

Jones HN, Powell TL, Jansson T. IL-6 stimulates System A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2. Am J Physiol Cell Physiol. 2009;297(5):C1228-35.

Jones HN,Woollett LA, Barbour N, Prasad PD, Powell TL, Jansson T. High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice. FASEB J. 2009;23(1):271-8.

McArdle HJ, Andersen HS, Jones H, Gambling L. Copper and iron transport across the placenta: regulation and interactions. J Neuroendocrinol. 2008;20(4):427-31.

Jones HN, Powell TL, Jansson T. Regulation of Placental Nutrient Transport – A Review. Placenta. 2007;28l; 763- 774.

Ferguson-Smith AC, Moore T, Detmar J, Lewis A, Hemberger M, Jammes H, Kelsey G, Roberts CT, Jones H, Constancia M. Epigenetics and imprinting of the trophoblast -- a workshop report. Placenta. 2006;Suppl A:S122-6.

McArdle HJ, Andersen HS, Jones H, Gambling L. Fetal Programming: Causes and Consequences as Revealed by Studies of Dietary Manipulation in Rats – A Review. Placenta. 2006;27:56-60.

Jones HN, Ashworth CJ, Page KR, McArdle HJ. Cortisol stimulates System A amino acid transport and SNAT2 expression in a human placental cell line (BeWo). Am. J. Physiol Endocrinology and Metabolism. 2006;291(3):E596-603.

Jones HN, Ashworth CJ, Page KR, McArdle HJ. Expression and adaptive regulation of amino acid transport system A in a placental cell line under amino acid restriction. Reproduction. 131:951-60, 2006.