Nicolas Nassar, PhD

Associate Professor, UC Department of Pediatrics

Phone: 513-636-6597


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Nicolas Nassar, PhD is a structural biologist interested in the structure/function of signaling proteins and in finding ways to inhibit their signaling in disease. More specifically, we are interested in how a given protein specifically binds and recognizes its regulators and targets. We have over the years focused on Ras-like GTPases. Recently, however we have been interested in a new family of protein tyrosine phosphatases (PTPs). We combine X-ray crystallography, site-directed mutagenesis, enzyme kinetics, and other biophysical techniques in our studies.

Education and Training

PhD: University Joseph Fourier, Grenoble – France (1992).

Postdoc: Max Plank Institut, Dortmund – Germany (1996).

Research Associate: Cornell University, Ithaca – NY (2000). 

Assistant Professor: Stony Brook University, NY (2006). 

Research Assistant Professor: Stony Brook University (2010).