Surgical treatment of fetal and newborn diseases; open and minimally invasive fetal surgery; congenital lung and airway disease; congenital esophageal disease; sacrococcygeal teratoma; conjoined twins and neonatal surgery; mechanisms of long-term immunologic tolerance to prenatally transplanted stem cells; developmental hematology, pluripotent stem cell biology; fetal gene therapy
Dr. Shaaban served as an associate professor of surgery with tenure and as director of the Laboratory for Fetal Cellular Therapy at the University of Iowa Carver College of Medicine from 2008-2012. Prior to that he served as director of the Laboratory for Fetal Cellular Therapy at University of Wisconsin College of Medicine from 2002-2008.
Education and Training
MD: University of Illinois College of Medicine, Chicago, IL, 1991.
Residency: General Surgery, University of Iowa Hospital and Clinics; Pediatric Surgery, The Children’s Hospital of Philadelphia.
Fellowship: Fetal Surgery Research, Children’s Hospital of Philadelphia; Fetal Surgery, Children’s Hospital of Philadelphia.
Certification: Surgery 1998, 2011; Pediatric Surgery, 2006.
View PubMed Publications
Al-Hajjat A, Durkin ET, Shaaban AF. Regulation of the earliest immune response to in utero hematopoietic cellular transplantation. Chimerism. 2011;1(2):1-3.
Delgado D, Webster DE, DeSantes KB, Durkin ET, Shaaban AF. KIR receptor-ligand incompatibility predicts killing of osteosarcoma cells by allogeneic NK cells. Pediatric Blood and Cancer. 2010;55(7):1300-5.
Durkin ET, Jones KA, Elnaggar D, Rajesh D, Shaaban AF. Early chimerism threshold predicts sustained engraftment in prenatal allogeneic chimeras. Blood. 2008 Dec 15;112(13):5245-53.
Durkin ET, Schroth MK, Helin MD, Shaaban AF. Early laparoscopic fundoplication and gastrostomy in infants with spinal muscular atrophy type I. Journal of Pediatric Surgery. 2008 Nov;43(11):2031-7.
Shaaban A, Heise C. Posterior Sagittal Anorectoplasty for Congenital Rectovaginal Malformations in the Adult. Dis Colon Rectum. 2008 Oct;51(10):1569.
Ibele A, Flake AW, Shaaban AF. Survival of a fetus with sacrococcygeal teratoma and non-immune hydrops delivered at 27 weeks for maternal MIRROR syndrome. Journal of Pediatric Surgery. 2008 Aug;43(8):e17-20.
Durkin ET, Lund, DP, Shaaban AF, Schurr, MJ, Weber SW. Age-Related Differences in the Diagnosis and Morbidity of Intestinal Malrotation. Journal of the American College of Surgeons. 2008 Apr;206(4):658-63.
Durkin ET, Jones KA, Elnaggar D, Shaaban AF. Donor class I expression determines the outcome of prenatal transplantation. Journal of Pediatric Surgery. 2008 Jun;43(6):1142-7.
Durkin ET, Krawiec M, Shaaban AF. Thoracoscopic aortopexy for primary tracheomalacia in an adolescent. Journal of Pediatric Surgery. 2007 Jul;42(7): E15-7.
Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin II, Thomson JA, Shaaban AF. Differential Requirements for Hematopoietic Commitment between Human and Rhesus Embryonic Stem Cells. Stem Cells. 2007;25:490-499.
NK cell response to prenatal allotransplantation. Principal Investigator. National Heart, Lung and Blood Institute. 2011 - 2016.