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Vincent J. Schmithorst, PhD

Assistant Professor, Division of Pediatric Radiology

Phone 513-636-3922

Fax 513-636-0434


Cortical Reorganization in children with unilateral sensorineural hearing loss using functional magnetic resonance imaging (fMRI); the development of language function in children using fMRI; white matter maturation in children's brains using diffusion tensor imaging (DTI); analysis techniques for fMRI data and functional connectivity

Dr. Schmithorst is a physicist by training with BS, MS, and PhD degrees from the University of Cincinnati. Schmithorst's thesis was on utilizing an ionizing radiation detector in digital projection radiography to separate bone from soft-tissue components using information from the penetration depth of the x-ray beam.

Dr. Schmithorst came to the Imaging research Center in the Fall of 1997. He is currently engaged in research projects involving the:

  • Development of language function and math processing in children using functional magnetic resonance imaging (fMRI)
  • Investigation of the correlation of musical training with math ability on school-age children using fMRI, white matter maturation in children's brains using diffusion tensor imaging (DTI)
  • Development of appropriate fMRI data acquisition and post-processing techniques in subjects with developmental or acquired communication disorders
  • Use of information-theoretic methods, such as Independent Component Analysis (ICA), for analysis for fMRI data

As part of his research efforts, Schmithorst has authored Cincinnati Children's Hospital Image Processing Software (CCHIPS), an extensive software suite for MRI image reconstruction and post-processing in the Interactive Data Language (IDL) programming environment. CCHIPS is available free of charge for research purposes only to all interested parties.

PhD: University of Cincinnati, Cincinnati, OH, 1997.

View PubMed Publications.

Schmithorst VJ, Holland SK, Plante E. Diffusion tensor imaging reveals white matter microstructure correlations with auditory processing ability. Ear Hear. 2011 Mar-Apr;32(2):156-67.

Propst EJ, Greinwald JH, Schmithorst V. Neuroanatomic differences in children with unilateral sensorineural hearing loss detected using functional magnetic resonance imaging. Arch Otolaryngol Head Neck Surg. 2010 Jan;136(1):22-6.

Vannest J, Rasmussen J, Eaton KP, Patel K, Schmithorst V, Karunanayaka P, Plante E, Byars A, Holland S. FMRI activation in language areas correlates with verb generation performance in children. Neuropediatrics. 2010 Oct;41(5):235-9.

Karunanayaka P, Schmithorst VJ, Vannest J, Szaflarski JP, Plante E, Holland SK. A group independent component analysis of covert verb generation in children: a functional magnetic resonance imaging study. NeuroImage. 2010 May 15;51(1):472-87.

Schmithorst VJ, Yuan W. White matter development during adolescence as shown by diffusion MRI. Brain Cogn. 2010 Feb;72(1):16-25.

Brubaker CJ, Schmithorst VJ, Haynes EN, Dietrich KN, Egelhoff JC, Lindquist DM, Lanphear BP, Cecil KM. Altered myelination and axonal integrity in adults with childhood lead exposure: a diffusion tensor imaging study. Neurotoxicology. 2009 Nov;30(6):867-75.

Vannest J, Karunanayaka PR, Schmithorst VJ, Szaflarski JP, Holland SK. Language networks in children: evidence from functional MRI studies. AJR Am J Roentgenol. 2009 May;192(5):1190-6.

Vannest JJ, Karunanayaka PR, Altaye M, Schmithorst VJ, Plante EM, Eaton KJ, Rasmussen JM, Holland SK. Comparison of fMRI data from passive listening and active-response story processing tasks in children. J Magn Reson Imaging. 2009 Apr;29(4):971-6.

Schmithorst VJ, Altes TA, Young LR, Franz DN, Bissler JJ, McCormack FX, Dardzinski BJ, Brody AS. Automated algorithm for quantifying the extent of cystic change on volumetric chest CT: initial results in Lymphangioleiomyomatosis. AJR Am J Roentgenol. 2009 Apr;192(4):1037-44.

Schmithorst VJ. Developmental sex differences in the relation of neuroanatomical connectivity to intelligenceIntelligence. 2009 Mar;37(2):164-173.