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High Res

John J. Bissler, MD

Associate Program Director for Research and Academic Careers

Clark D. West Chair of Nephrology

Director, Nephrology Fellowship Training Program

Professor, UC Department of Pediatrics

Phone: 513-636-1201

Fax: 513-636-7407

Email: john.bissler@cchmc.org

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Specialties

Clinical Interests

Proliferative renal diseases; renal cystic disease; solid lesions

Research Interests

Proliferative renal diseases; polycystic kidney disease; tuberous sclerosis complex; Von Hippel-Lindau disease; Birt-Hogg-Dube syndrome and renal cancers; understanding the mechanisms of mutation leading to these diseases as well as the consequences of mutations in hope of finding effected treatments

Visit the Bissler Lab.

Education and Training

MD: Northeastern Ohio University College of Medicine, Rootstown, OH, 1985

Residency: Pediatrics, Children's Medical Center, Akron, OH

Fellowship: Nephrology, Children's Hospital Medical Center, Cincinnati, OH

Certification: Pediatrics, 1989; Pediatric Nephrology, 1992

Publications

View PubMed Publications

Dixon BP, Hulbert JC, and Bissler JJ. Tuberous Sclerosis Complex Renal Disease. Nephron. 2011;118(1):e15-20.

Siroky BJ, Yin H, Bissler JJ. Molecular Insights into Tuberous Sclerosis Complex Renal Disease. Pediatric Nephrol. 2010 Dec 9.

Mrug M, and Bissler JJ. Simulation of real-time ultrasound-guided renal biopsy. Kidney Int. 2010 Oct;78(7):705-7.

Bissler JJ, Siroky BJ, Yin H. Glomerulocystic kidney disease. Pediatric Nephrol. 2010 Oct;25(10):2049-56; quiz 2056-9.

Liu G, Bissler JJ, Sinden RR, Leffak M. Replication dependent instability at (CTG)•(CAG) repeat hairpins in human cells. Nat Chem Biol. 2010 Sep;6(9):652-9.

Johnson SR, and the Review Panel of the European Respiratory Society Lymphangioleiomyomatosis Task Force. European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis. Eur Respir J. 2010;35:14-26.

Siroky BJ, Czyzyk-Krzeska MF, Bissler JJ. Renal involvement in tuberous sclerosis complex and von Hippel-Lindau disease: shared disease mechanisms? Nat Clin Pract Nephrol. 2009;5(3):143-56.

Schmithorst VJ, Altes TA, Young LR, Franz DN, Bissler JJ, McCormack FX, et al. Automated algorithm for quantifying the extent of cystic change on volumetric chest CT: initial results in Lymphangioleiomyomatosis . Am J Roentgenol. 2009;192(4):1037-44.

Dixon BP, Chu A, Henry J, Kim R, Bissler JJ. Increased cancer risk of augmentation cystoplasty: Possible role for hyperosmolal microenvironment on DNA damage recognition . Mutat Res. 2009; 670:88-95.

Book Chapters

Bissler JJ, Henske E. Tuberous Sclerosis Complex: From Genes to Therapeutics. Chapter 15. Renal Manifestations of Tuberous Sclerosis Complex. In: Whittemore V, Henske EP, Kwiatkowski D, editors. New York: Elsevier; 2009.