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Biographies

Find another Doctor or Researcher

High Res

Melinda Butsch Kovacic, MPH, PhD

Assistant Professor, UC Department of Pediatrics

Phone: 513-803-0130

Fax: 513-636-1657

Email: but4no@cchmc.org

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Specialties

Personalized medicine; genetic and environmental biomarkers of asthma and allergic disease; human papillomavirus infection and cancer; fanconi anemia

Biography

Melinda Butsch Kovacic, MPH, PhD has a long-term goal to make an important contribution towards improving health of children and families in the United States using molecular epidemiologic approaches and innovative laboratory and clinical research methods. Her current funded research seeks to identify genetic and environmental biomarkers of asthma and allergic disease with the goal of developing more personalized prevention strategies and tailored treatment options. In addition, Dr. Butsch Kovacic is exploring the prevalence of human papillomavirus infection in children and adults with Fanconi Anemia compared to healthy related and unrelated controls in collaboration with members of Hematology / Oncology.

Education and Training

MPH: Quantitative Methods. Harvard University School of Public Health, Boston, MA, 2003.

PhD: Biochemistry, the Ohio State University, Columbus, OH, 2002.

Postdoctoral Fellowship: Epidemiology/Public Health, Cancer Prevention Fellowship, Hormonal and Reproductive Epidemiology Branch, Division of of Cancer Epidemiology and Genetics, National Cancer Institute, 2002-2006.

Publications

View PubMed Publications

Myers KC, Bleesing JJ, Davies SM, Zhang X, Martin LJ, Mueller R, Harris RE, Filipovich AH, Kovacic MB, Wells SI, Mehta PA. Impaired immune function in children with Fanconi anaemia. Br J Haematol. 2011 Jul;154(2):234-40.

Cortina SD, Drotar D, Ericksen M, Lindsey M, Patterson TL, Biagini Myers JM, Kovacic MB, Khurana Hershey GK. Genetic Biomarkers of Health-Related Quality of Life in Pediatric Asthma. J Pediatr. 2011 Jul;159(1):21-26.e1.

Reszka KJ, Sallans L, Macha S, Brown K, McGraw DW, Kovacic MB, Britigan BE. Airway peroxidases catalyze nitration of the {beta}2-agonist salbutamol and decrease its pharmacological activity. J Pharmacol Exp Ther. 2011 Feb;336(2):440-9.

Sherrill JD, Gao PS, Stucke EM, Blanchard C, Collins MH, Putnam PE, Franciosi JP, Kushner JP, Abonia JP, Assa'ad AH, Kovacic MB, Biagini Myers JM, Bochner BS, He H, Hershey GK, Martin LJ, Rothenberg ME. Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. J Allergy Clin Immunol. 2010 Jul;126(1):160-5.e3.

Morreale RJ, Kahn JA, Butsch Kovacic M, Hegde RS, Aronow BJ, Wells SI. Insights from the transcriptional profiling of human papillomavirus infection and associated carcinogenesis. Molecular Biology of Tumor Virus Gene Products. 2009.

Butsch Kovacic M, Katki H, Kreimer A, Sherman, ME. Epidemiologic Analysis of Histologic Cervical Inflammation: Relationship to Human Papillomavirus Infections. Human Pathology. 2008 Jul;39(7):1088-95. Epub 2008 May 20.

Gravitt P, Butsch Kovacic M, Castle PE, Herrero R, Schiffman M, Concepción Bratti M, Hildesheim A, Morales J, Alfaro M, Sherman ME, Wacholder, Rodriguez AC, Burk RD. Viral Load of Human Papillomavirus Type 16 is Uniquely Associated with Cervical Disease. Inter. Int J of Cancer. 2007;121(12):2787-93.

Bolinger C, Yilmaz A, Hartman TR, Kovacic MB, Fernandez S, Ye J, Forget M, Green PL, Boris-Lawrie K. RNA helicase A interacts with divergent lymphotropic retroviruses and is necessary for human T-cell leukemia virus type 1 replication. Nucleic Acids Research. 2007;35(8):2629-42.

Kovacic MB, Castle PE, Herrero R, Schiffman M, Sherman ME, Wacholder S, Rodriguez AC, Hutchinson ML, Bratti MC, Hildesheim A, Morales J, Alfaro M, Burk RD. Relationships of Human Papillomavirus Type, Qualitative Viral Load & Age to Cytologic Abnormality. Cancer Research. 2006;66(20):10112-9.