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Samantha A. Brugmann, PhD

Assistant Professor, UC Department of Pediatrics

Phone: 513-636-7678

Email: samantha.brugmann@cchmc.org

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Specialties

Craniofacial development

Visit the Brugmann Lab.

Biography

Samantha A. Brugmann, PhD, is an assistant professor of pediatrics in the Divisions of Plastic Surgery and Developmental Biology. She received her BS in Cell & Molecular Biology in 1998 from Tulane University in New Orleans, LA. She then moved to Washington, DC to study cranial sensory placode development in Xenopus laevis at George Washington University. After receiving her PhD in Genetics from George Washington University in 2004, she moved to Stanford, CA to do her postdoctoral research in craniofacial development at Stanford University. While at Stanford she received a Ruth L. Kirschstein National Research Service Awards for Individual Postdoctoral Fellows (F32) in 2006, a Pediatric Research Fund-Child Health Research Program Grant in 2009 and a NIH Pathway to Independence Award (K99/R00) in 2010. She joined Cincinnati Children’s Hospital in January 2011 to study craniofacial development and disease.

Education and Training

BS: Tulane University, New Orleans, LA, 1998.

PhD: George Washington University, Washington DC, 2004.

Fellowship: Stanford University, Stanford, CA, 2004-2010.

Publications

View PubMed Publications

Zaghloul NA, Brugmann SA. The emerging face of primary cilia. Genesis. 2011 Apr;49(4):231-46.

Levi B, James AW, Nelson ER, Brugmann SA, Sorkin M, Manu A, Longaker MT. Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-90.

Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J. A unique chromatin signature uncovers early developmental enhancers in humans. Nature. 2011 Feb 10;470(7333):279-83.

Cordero DR, Brugmann S, Chu Y, Bajpai R, Jame M, Helms JA. Cranial neural crest cells on the move: their roles in craniofacial development. Am J Med Genet A. 2011 Feb;155(2):270-9.

Brugmann SA, Cordero DR, Helms JA. Craniofacial ciliopathies: A new classification for craniofacial disorders. Am J Med Genet A. 2010 Dec;152A(12):2995-3006.

Brugmann SA, Allen NC, James AW, Mekonnen Z, Madan E, Helms JA. A primary cilia-dependent etiology for midline facial disorders. Hum Mol Genet. 2010 Apr 15;19(8):1577-92.

Brugmann SA, Powder KE, Young NM, Goodnough LH, Hahn SM, James AW, Helms JA, Lovett M. Comparative gene expression analysis of avian embryonic facial structures reveals new candidates for human craniofacial disorders. Hum Mol Genet. 2010 Mar 1;19(5):920-30.

Brugmann SA, Goodnough LH, Gregorieff A, Leucht P, ten Berge D, Fuerer C, Clevers H, Nusse R, Helms JA. Wnt signaling mediates regional specification in the vertebrate face. Development. 2007 Sep;134(18):3283-95.

Brugmann SA, Kim J, Helms JA. Looking different: understanding diversity in facial form. Am J Med Genet A. 2006 Dec 1;140(23):2521-9.

Brugmann SA, Tapadia MD, Helms JA. The molecular origins of species-specific facial pattern. Curr Top Dev Biol. 2006;73:1-42.