Biographies

Jamie K. Capal, MD

Pediatric Neurologist, Division of Neurology

Assistant Professor, UC Department of Pediatrics

Phone: 513-636-4222

Email: jamie.capal@cchmc.org

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Specialties

Clinical

Child neurology; developmental pediatrics; autism; tuberous sclerosis

Research

Autism spectrum disorders; tuberous sclerosis

Biography

Dr. Capal’s clinical and research interests focus on children with autism spectrum disorders and related neurodevelopmental conditions. Current research projects include understanding the cognitive, behavioral, and language aspects of children with autism spectrum disorders and abnormal EEG but not always with concurrent clinical seizures. A natural extension of my research has led to interest in tuberous sclerosis complex (TSC), where autism, abnormal EEG, and seizures are frequent and interdependent. The genetic and molecular basis of TSC is well established, which provides an ideal platform for further investigation into the underlying mechanisms responsible and, in turn, discover new molecular-based targeted therapies. The TSC Clinic at Cincinnati Children’s Hospital Medical Center is the largest of its kind in the world, providing comprehensive, multidisciplinary clinical care to TSC patients of any age. This work led efforts that resulted in the first ever FDA-approved medical therapy for TSC in 2010 using the mTOR inhibitor everolimus. Our long-term goal is to refine and apply these and next-generation therapies for patients with TSC.

Education and Training

BA: Biology with Honors, Ithaca College, Ithaca, NY, 2002.

MD: Albany Medical College, Albany, NY, 2002.

Internship: Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2006-2007.

Residency: Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2007-2008.

Resident/Fellow: Pediatric Neurodevelopmental Disabilities, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2008-1012.

Publications