Add to MyPages

This page will be saved to Cincinnati Children's MyPages, a collection of your favorite places. You can view, organize, or delete your favorites at any time.

Page Title:

Description: (optional)

E-mail this page

(All fields required)

Recipient's e-mail address

Please enter a valid e-mail.

Your name

Please enter your name.

Your e-mail

Please enter a valid e-mail.

Share this on:

Sign into CCHMC

User Name

Password

Forgot Password

Biographies

Find another Doctor or Researcher

A photo of Doctor Jose Cancelas Perez.

High Res

Jose A. Cancelas Perez, MD, PhD

Director of Research, Hoxworth Blood Center

Director of Flow Core

Associate Professor, UC Department of Pediatrics

Phone: 513-558-1324

Fax: 513-558-1522

Email: jose.cancelas@uc.edu

Show All

Specialties

Hematopoietic stem cell proliferation and differentiation

Visit the Cancelas Lab.

Education and Training

MD: Autonomous University of Madrid, Spain, 1989.

Residency: Hematology and Hematotherapy, University of Alcala de Henares, Madrid, Spain, 1993.

PhD: Faculty of Medicine, University of Alcala de Henares, Madrid, Spain, 1996.

Publications

View PubMed Publications

Ryan MA, Nattamai KJ, Xing E, Schleimer D, Daria D, Sengupta A, Köhler A, Liu W, Gunzer M, Jansen M, Ratner N, Le Cras TD, Waterstrat A, Van Zant G, Cancelas JA, Zheng Y, Geiger H. Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization. Nat Med. 2010 Oct;16(10):1141-6. Epub 2010 Sep 26.

Sengupta A, Cancelas JA. Cancer stem cells: a stride towards cancer cure? J Cell Physiol. 2010 Oct;225(1):7-14. Review.

Sengupta A, Arnett J, Dunn S, Williams DA, Cancelas JA. Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo. Blood. 2010 Jul 8;116(1):81-4. Epub 2010 Apr 20.

Kalfa TA, Pushkaran S, Zhang X, Johnson JF, Pan D, Daria D, Geiger H, Cancelas JA, Williams DA, Zheng Y. Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen. Haematologica. 2010 Jan;95(1):27-35.

Mulloy JC, Cancelas JA, Filippi MD, Kalfa TA, Guo F, Zheng Y. Rho GTPases in hematopoiesis and hemopathies. Blood. 2010 Feb 4;115(5):936-47. Epub 2009 Nov 24. Review.

Miller SJ, Lan ZD, Hardiman A, Wu J, Kordich JJ, Patmore DM, Hegde RS, Cripe TP, Cancelas JA, Collins MH, Ratner N. Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis. Oncogene. 2010 Jan 21;29(3):368-79. Epub 2009 Nov 9.

Sanchez-Aguilera A, Rattmann I, Drew DZ, Müller LU, Summey V, Lucas DM, Byrd JC, Croce CM, Gu Y, Cancelas JA, Johnston P, Moritz T, Williams DA. Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia. Leukemia. 2010 Jan;24(1):97-104. Epub 2009 Oct 22.

Yamada Y, Cancelas JA, Rothenberg ME. Murine model of hypereosinophilic syndromes/chronic eosinophilic leukemia. Int Arch Allergy Immunol. 2009;149 Suppl 1:102-7. Epub 2009 Jun 3. Review.

Milsom MD, Lee AW, Zheng Y, Cancelas JA. Fanca-/- hematopoietic stem cells demonstrate a mobilization defect which can be overcome by administration of the Rac inhibitor NSC23766. Haematologica. 2009 Jul;94(7):1011-5. Epub 2009 Jun 2.

Cancelas JA, Williams DA. Rho GTPases in hematopoietic stem cell functions. Curr Opin Hematol. 2009 Jul;16(4):249-54. Review.

Grants

Gap Junction Intercellular Communication in Bone Marrow Failure. Principal Investigator. Department of Defense Army. Apr 2011 - Nov 2012. #W81XWH1110296.

Rac GTPase Inhibition in Chronic Myelogenous Leukemia. Principal Investigator. National Institutes of Health. Apr 2009 - Mar 2013. #R01 HL 087159.

Related Professionals

Doctors & Researchers

© 1999-2011 Cincinnati Children's Hospital Medical Center

3333 Burnet Avenue, Cincinnati, Ohio 45229-3026 | 1-513-636-4200 | 1-800-344-2462 | TTY:1-513-636-4900