Lionel M.L. Chow, MD, PhD

Member, Cancer Biology and Neural Tumors Program

St. Baldrick’s Foundation Scholar

Sontag Foundation Distinguished Scientist

Assistant Professor, UC Department of Pediatrics

Phone: 513-803-1369

Fax: 513-636-3549


Show All


Clinical Interests

Pediatric neuro-oncology

Research Interests

Mouse models for glioma; molecular profiling of tumor mutations; biomarkers of tumor progression; novel therapeutic agents for glioma

Visit the Chow Lab


Lionel Chow, MD, PhD, received his medical and graduate degrees from McGill University in Montreal, Canada, where his research focused on the regulation of T-lymphocyte signaling by the intracellular tyrosine protein kinases Lck and Csk.

Following his clinical training in pediatrics and pediatric hematology / oncology at the Hospital for Sick Children in Toronto, Canada, he moved to St. Jude Children’s Research Hospital in Memphis, Tenn., to pursue his research interests.

Chow's research interests have been centered on glioblastoma multiforme, a particularly devastating form of cancer in adults and children. His work has resulted in the development of a number of novel and robust laboratory models for this disease. Using these models and interfacing with clinical trials in the Neuro-Oncology Program as well as those from national consortia such as the Children's Oncology Group (COG) and the Pediatric Brain Tumor Consortium (PBTC), Chow’s laboratory will continue research in this area with the goals of better understanding the origins of this form of cancer and improving patient outcomes.

Education and Training

PhD: McGill University, Montreal, Quebec, Canada, 1996.

MDCM: McGill University, Montreal, Quebec, Canada, 1997.

Residency: The Hospital for Sick Children, University of Toronto, Toronto, Canada, 1997-2000.

Clinical Fellowship: The Hospital for Sick Children, University of Toronto, Toronto, Canada, 2000-2003.

Postdoctoral Fellowship: St. Jude Children’s Research Hospital, Memphis, TN, 2003-2009.

Clinical Fellowship: St. Jude Children’s Research Hospital, Memphis TN, 2008-2009.

Certification: Pediatrics, 2000.


View PubMed Publications


2013 – 2014 Sophie’s Angel Run Foundation
“Preclinical Testing of Notch and mTor Inhibition in a Mouse Model for High-Grade Glioma” 

2011 – 2014 St. Baldrick’s Foundation Scholars Award
"Molecular targeting of pediatric high-grade glioma"

2011 – 2015 Sontag Foundation Distinguished Scientist Award
"Molecular targeting of high-grade astrocytoma"