Ranjit S. Chima, MD

Assistant Professor, UC Department of Pediatrics

Phone 513-636-4259

Fax 513-636-4267

Email ranjit.chima@cchmc.org

Critical Illness following stem cell transplantation; extracorporeal life support; venous thromboembolism; critical Illness hyperglycemia

MBBS: Grant Medical College, Mumbai, India, 1996.

MD: Pediatrics, University of Mumbai, Mumbai, India, 1999.

Residency: Pediatrics, University of Mumbai, Mumbai, India, 1996-1999; Pediatrics, Children's Hospital of Michigan, Detroit, MI, 2001-2004.

Fellowship: Critical Care Medicine, Cincinnati Childrens Hospital Medical Center, 2004-2007.

Certification: Pediatrics, 2004; Pediatric Critical Care Medicine, 2008

Jodele S, Hirsch R, Laskin B, Davies S, Witte D, Chima R. Pulmonary arterial hypertension in pediatric patients with hematopoietic stem cell transplant-associated thrombotic microangiopathy. Biol Blood Marrow Transplant. 2013 Feb;19(2):202-7. PMID: 22960385.

Chima RS, Daniels RC, Kim MO, Li D, Wheeler DS, Davies SM, Jodele S. Improved outcomes for Stem Cell Transplant Recipients Requiring Pediatric Intensive Care. Pediatric Critical Care Medicine. 2012 Nov. 13 (6):e336-42. PMID:22791094. 

Chima RS, Schoettker PJ, Varadarajan KR, Kloppenborg E, Hutson TK, Brilli RJ, Repaske DR, Seid M. Reduction in hypoglycemic events in critically ill patients on continuous insulin following implementation of a treatment guideline. Qual Manag Health Care. 2012 Jan-Mar;21(1):20-8.  PMID: 22207015. 

Raake J, Johnson B, Seger B, Manning PB, Eghtesady P, Boesch P, Rutter M, Woodard A, Chima RS. Tracheal Dehiscence following Slide Tracheoplasty: Use of  ECMO, Prolonged Extubation and Lung Recruitment Maneuvers to Optimize Patient Outcomes. Respir Care. 2011 Aug;56(8):1198-202. PMID: 21496362. 

Chima RS, LaMontagne T, Piraino G, Hake PW, Denenberg A, Zingarelli B. C-peptide, a Novel Inhibitor of Lung Inflammation following Hemorrhagic Shock. Am J Physiol Lung Cell Mol Physiol. 2011 May;300(5):L730-9. PMID: 21398498. 

Chima RS, Maltese G, LaMontagne T, Piraino G, Denenberg A, O’Connor M, Zingarelli B. C-Peptide ameliorates Kidney Injury following Hemorrhagic Shock. Shock. 2011 May; 35(5):524-9. PMID: 21263384. 

Wong HR, Wheeler DS, Tegtmeyer K, Poynter SE, Kaplan JM, Chima RS, Stalets E, Basu RK, Doughty LA. Toward a clinically feasible gene expression-based sub-classification strategy for septic shock:  proof of concept. Crit Care Med. 2010 Oct; 38 (10): 1955-61. PMID: 20639748. 

Chima RS, Hake PW, Piraino G, Mangeshkar P, O’Connor M, Zingarelli B. Ciglitazone, a novel inhibitor of lung apoptosis following hemorrhagic shock. Int J Clin Exp Med 2010; 3(1):1-9. PMID: 20369035. 

Zingarelli B, Chima R, O'Connor M, Piraino G, Denenberg A, Hake PW. Liver apoptosis is age-dependent and is reduced by activation of peroxisome proliferator activated receptor in hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol. 2010 Jan 1; 298(1):G133-41. PMID: 19926821.

Chima RS, Hake P, Mangeshkar P, Piraino G, Denenberg A, Zingarelli B. Ciglitazone ameliorates lung inflammation by modulating the inhibitor kappaB protein kinase/nuclear factor-kappaB pathway after hemorrhagic shock. Crit. Care Med. 2008 36(10): 2849-2857. PMID: 18828195.

Heart and Lung Failure-Pediatric Insulin Titration Trial. Site Principal Investigator. National Institutes of Health, National Heart, Lung and Blood Institute (NHLBI). July 2012-present.