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Doctor Chen is an Assistant Professor at Cincinnati Children's.

High Res

Weiguo Chen, MD, PhD

Assistant Professor, UC Department of Pediatrics

Phone: 513-636-4752

Fax: 513-636-1657

Email: weiguo.chen@cchmc.org

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Specialties

Asthma; allergy and immunology

Education and Training

MD: Shanghai Medical University, China, 1985.

MS: Biochemistry, Shanghai Medical University, China, 1990.

PhD: Cell and Molecular Biology, University of Cincinnati, OH, 2000.

Postdoctoral: University of California at Berkeley, Berkeley, CA, 2000-2001; Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2001-2008.

Publications

View PubMed Publications

Sivaprasad U, Warrier MR, Gibson AM, Chen W, Tabata Y, Bass SA, Rothenberg ME, Khurana Hershey GK. IL-13Rα2 has a protective role in a mouse model of cutaneous inflammation. J Immunol. 2010 Dec 1;185(11):6802-8. Epub 2010 Oct 22.

Chen W, Sivaprasad U, Tabata Y, Gibson AM, Stier MT, Finkelman FD, Hershey GK. IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice. J Immunol. 2009 Dec 15;183(12):7870-6.

Chen W, Tabata Y, Gibson AM, Daines MO, Warrier MR, Wills-Karp M, Khurana Hershey GK. Matrix metalloproteinase-8 contributes to solubilization of interleukin-13 receptor alpha-2 in vivo. Journal of Allergy and Clinical Immunology. 2008;122(3):625-632.

Chen W, Khurana Hershey GK. Signal transducer and activator of transcription signals in allergic disease. Journal of Allergy and Clinical Immunology. 2007;119(3):529-541.

Daines MO, Chen W, Tabata Y, Walker BA, Gibson AM, Masino JA, Warrier MR, Daines CL, Wenzel SE, Hershey GK. Allergen-dependent solubilization of IL-13 receptor alpha2 reveals a novel mechanism to regulate allergy. Journal of Allergy and Clinical Immunology. 2007;119(2):375-83.

Tabata Y, Chen W, Warrier MR, Gibson AM, Daines MO, Hershey GK. Allergy-driven alternative splicing of IL-13 receptor alpha2 yields distinct membrane and soluble forms. Journal of Immunology. 2006;177(11):7905-7912.

Daines MO, Tabata Y, Walker BA, Chen W, Warrier MR, Basu S, Hershey GK. Level of expression of interleukin-13 receptor alpha 2 impacts receptor distribution and IL-13 signaling. Journal of Immunology. 2006;176(12):7495-7501.

Ponthier JL, Schluepen C, Chen W, Lersch RA, Gee SL, Hou VC, Lo AJ, Short SA, Chasis JA, Winkelmann JC, Conboy JC. Fox-2 splicing factor binds to a conserved intron motif to promote inclusion of protein 4.1R alternative exon 16. Journal of Biological Chemistry. 2006;281:12468-12474.