Sanjoy K. Das, PhD

Professor, UC Department of Pediatrics

Phone 513-803-1159

Fax 513-803-1160

Email sanjoy.das@cchmc.org

Characterization of non-genomic actions of natural estrogen and xenoestrogens in the uterus without involving the nuclear ERa and ERb; aspects of uterine cell cycle regulation for decidualization in implantation

Visit the Das Lab.

PhD: Biochemistry, University of Calcutta, Calcutta, India.

MSc: Biochemistry, University of Calcutta, Calcutta, India.

BSc: Chemistry (Honors), University of Calcutta, Calcutta, India.

Gao F, Ma X, Ostmann AB, Das SK. GPR30 activation opposes estrogen-dependent uterine growth via inhibition of stromal ERK1/2 and estrogen receptor alpha (ERα) phosphorylation signals. Endocrinology. 2011 Apr;152(4):1434-47.

Das SK. Regional development of uterine decidualization: molecular signaling by Hoxa-10. Mol Reprod Dev. 2010 May;77(5):387-96. Review.

Das SK. Cell cycle regulatory control for uterine stromal cell decidualization in implantationReproduction. 2009 Jun;137(6):889-99.

Davies SM, Borowitz MJ, Rosner GL, Ritz K, Devidas M, Winick N, Martin PL, Bowman P, Elliott J, Willman C, Das S, Cook EH, Relling MV. Pharmacogenetics of minimal residual disease response in children with B-precursor acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood. 2008 Mar 15;111(6):2984-90.

Ray S, Xu F, Wang H,  Das SK. Cooperative Control via Lymphoid Enhancer Factor 1/T Cell Factor 3 and Estrogen Receptor-a for Uterine Gene Regulation by Estrogen. Molecular Endocrinology. 2008;22:1125-40.

Xie H, Tranguch S, Jia X, Zhang H, Das SK, Dey SK, Kuo CJ, Wang H. Inactivation of nuclear Wnt-b-catenin signaling limits blastocyst competency for implantation. Development. 2008;135:717-27.

Wang H, Xie H, Sun X, Tranguch S, Zhang H, Jia X, Wang D, Das SK, Desvergne B, Wahli W, Dubois RN, Dey SK. Stage-specific integration of maternal and embryonic Peroxisome Proliferator-activated Receptor d signaling is critical to pregnancy success. Journal of Biological Chemistry. 2007;282:37770-82.

Xie H, Wang H, Tranguch S, Iwamoto R, Mekada E, DeMayo FJ, Lydon JP, Das SK, Dey SK. Maternal heparin-binding-EGF deficiency limits pregnancy success in mice. Proceedings of the National Academy of Science USA. 2007;104:18315-20.

Ray S, Xu F, Li P, Sanchez NS, Wang H, Das SK. Increased level of cellular Bip critically determines estrogenic potency for a xenoestrogen kepone in the mouse uterus. Endocrinology. 2007;148:4774-85.