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Biographies

Find another Doctor or Researcher

John W. Elrod, PhD

Research Fellow, Division of Molecular Cardiovascular Biology

University of Cincinnati College of Medicine

Phone: 513-636-4809

Email: john.elrod@cchmc.org

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Specialties

Myocardial infarction; heart failure; cell death; ischemia-reperfusion injury; diabetes

Education and Training

PhD: Albert Einstein College of Medicine, Yeshiva University, Bronx, NY, 2007

Publications

View PubMed Publications

Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD. Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice. J Clin Invest. 2010 Oct 1;120(10):3680-7.

van Berlo JH, Elrod JW, van den Hoogenhof MM, York AJ, Aronow BJ, Duncan SA, Molkentin JD. The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circ Res. 2010 Oct 15;107(8):1032-40.

Lorts A, Schwanekamp JA, Elrod JW, Sargent MA, Molkentin JD. Genetic manipulation of periostin expression in the heart does not affect myocyte content, cell cycle activity, or cardiac repair. Circ Res. 2009 Jan 2;104(1):e1-7.

Elrod JW, Calvert JW, Gundewar S, Bryan NS, Lefer DJ. Cardiac Derived Nitric Oxide Promotes Distant Organ Protection: Evidence for an Endocrine Role of Nitrite. Proc Natl Acad Sci. 2008 Aug 12;105(32):11430-5.

Elrod JW, Harrell M, Flagg TP, Gundewar S, Magnuson MA, Nichols CG, Coetzee WA, Lefer DJ. Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury. Circulation. 2008 Mar 18;117(11):1405-13.

Elrod JW, Calvert JW, Morrison J, Doeller JE, Kraus DW, Tao L, Scalia R, Kiss L, Szabo C, Kimura H, Chow C, Lefer DJ. Hydrogen Sulfide Attenuates Myocardial Ischemia-Reperfusion Injury via Preservation of Mitochondrial Function. Proc Natl Acad Sci. 2007 Sep 25;104(39):15560-5.

Bryan NS, Calvert JW, Elrod JW, Gundewar S, Lefer DJ. Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury. Proc Natl Acad Sci. 2007 Nov 27;104(48):19144-9.

Elrod JW, Greer JJ, Lefer DJ. Sildenafil Mediated Acute Cardioprotection is Independent of the NO/cGMP Pathway. Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H342-7.

Elrod JW, Duranski MR, Langston W, Greer JJ, Tao L, Dugas TR, Kevil CG, Champion HC, Lefer DJ. eNOS gene therapy exacerbates hepatic ischemia-reperfusion injury in diabetes: a role for eNOS uncoupling. Circ Res. 2006 Jul 7;99(1):78-85.

Elrod JW, Greer JJ, Bryan NS, Langston W, Szot JF, Gebregzlabher H, Janssens S, Feelisch M, Lefer DJ. Cardiomyocyte-specific overexpression of NO synthase-3 protects against myocardial ischemia-reperfusion injury. Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1517-23.