Lin Fei, PhD

Professor, UC Department of Pediatrics

lin.fei@cchmc.org

About

Biography

As a professor and researcher, I design clinical and non-clinical studies, perform data analysis and presentation and examine mathematical modeling. My primary interests are probability and statistical theory applied to medical research, including distributional theory and optimization.

My interest in this field stems from my mathematical and statistical training and quantitative research. One of my notable discoveries is the probabilistic relationship between sample size and discovery rate in clinical studies, which can be reviewed in some of my publications.

I have been a researcher for over 29 years and began working with Cincinnati Children’s in 2012.

Interests

Statistics; ranking and selection; sequential testing; multiple comparisons; probability modeling; stochastic process inference

Research Areas

Biostatistics and Epidemiology

Publications

Percutaneous Electrical Nerve Field Stimulation in Children and Adolescents With Functional Dyspepsia-Integrating a Behavioral Intervention. Santucci, NR; Beigarten, AJ; Khalid, F; El-Chammas, KI; Graham, K; Sahay, R; Fei, L; Rich, K; Mellon, M. Neuromodulation. 2024; 27:372-381.

Psychological distress and coping efficacy in children with disorders of gut-brain interaction. Santucci, NR; Velasco-Benitez, CA; Cunningham, N; Li, J; Fei, L; Sun, Q; Saps, M. Neurogastroenterology and Motility. 2024; 36:e14724.

Predictive Value of Laryngeal Penetration to Aspiration in a Cohort of Pediatric Patients. Miller, AL; Miller, CK; Fei, L; Sun, Q; Willging, JP; de Alarcon, A; Pentiuk, SP. Dysphagia. 2024; 39:33-42.

Food Insecurity and Pediatric Nonalcoholic Fatty Liver Disease Severity. Orkin, S; Zhao, X; Setchell, KD R; Carr, E; Arce-Clachar, AC; Bramlage, K; Huang, R; Fei, L; Beck, AF; Fawaz, R; et al. The Journal of Pediatrics. 2024; 265:113818.

Real-Time Acute Kidney Injury Risk Stratification-Biomarker Directed Fluid Management Improves Outcomes in Critically Ill Children and Young Adults. Goldstein, SL; Krallman, KA; Roy, JP; Collins, M; Chima, RS; Basu, RK; Chawla, L; Fei, L. Kidney International Reports. 2023; 8:2690-2700.

Percutaneous electrical nerve field stimulation compared to standard medical therapy in adolescents with functional abdominal pain disorders. Santucci, NR; Sahay, R; El-Chammas, KI; Graham, K; Wheatley, M; Vandenbrink, M; Hardy, J; Fei, L. Frontiers in Pain Research. 2023; 4:1251932.

Racial Disparities in Pediatric Inflammatory Bowel Disease Care: Differences in Outcomes and Health Service Utilization Between Black and White Children. Smith, J; Liu, C; Beck, A; Fei, L; Brokamp, C; Meryum, S; Whaley, KG; Minar, P; Hellmann, J; Denson, LA; et al. The Journal of Pediatrics. 2023; 260:113522.

Presence of Alpha 1 Antitrypsin Risk Variants is Not Associated With Histologic Severity of Pediatric NAFLD. Khan, M; Klepper, C; Orkin, S; Arce-Clachar, AC; Bramlage, K; Fei, L; Miethke, A; Kohli, R; Xanthakos, S; Mouzaki, M. Journal of Pediatric Gastroenterology and Nutrition. 2023; 77:166-170.

Recent Increase in Incidence of Severe Acute Hepatitis of Unknown Etiology in Children is Associated with Infection with Adenovirus and Other Nonhepatotropic Viruses. Peters, AL; Kim, S; Mourya, R; Asai, A; Taylor, A; Rogers, M; Campbell, K; Fei, L; Miethke, A; Balistreri, WF; et al. The Journal of Pediatrics. 2023; 259:113439.

Novel sensory trigger for gastrocolonic response. Dorfman, L; Wongteerasut, A; El-Chammas, K; Sahay, R; Fei, L; Kaul, A. Neurogastroenterology and Motility. 2023; 35:e14528.