Alexandra (Lisa) H. Filipovich, MD

Ralph J. Stolle Chair, Clinical Immunology

Director, Immune Deficiency and Histiocytosis Program

Medical Director, Diagnostic Immunology Laboratory

Professor, UC Department of Pediatrics

Phone: 513-803-3218

Fax: 513-803-1969


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Clinical Interests

Primary immunodeficiencies; BMT for primary immunodeficiencies; hemophagocytic lymphocytosis; post-BMT immune reconstruction

Research Interests

Biology and genetics of hemophagocytic lymphohistiocytosis; investigation of hematopoietic cell transplantation for genetic immunodeficiencies; immunoreconstitution following pediatric stem cell transplantation


Lisa Filipovich, MD, began her career at the University of Minnesota where she received her medical degree in 1974 and completed fellowships in both immunopathology and pediatric immunology. She became a professor of pediatrics and served for 10 years as the head of the Division of Immunology at the University of Minnesota Medical School. Dr. Filipovich came to Cincinnati Children’s in 1996. She is currently the Ralph J. Stolle Chair in Clinical Immunology and the director of the Immune Deficiency and Histiocytosis program. She also serves as the medical director of the Diagnostic Immunology Laboratory at Cincinnati Children’s.

Dr. Filipovich has a special interest in histiocytic disorders, especially hemophagocytic lymphohistiocytosis (HLH). Other interests include bone marrow transplant for primary immune deficiencies and post-BMT immune reconstitution. She serves as president of the Histiocyte Society, an international group of more than 200 physicians and scientists who are committed to improving the lives of patients with histiocytosis through research.

Education and Training

MD: University of Minnesota, Minneapolis, MN, 1974.

Residency: University of Minnesota Hospitals, Minneapolis, MN 1975-1978.

Fellowship: Immunopathology, Departments of Pediatrics, Laboratory Medicine and Pathology, University of Minnesota 1978-1979.

Fellowship: Pediatric Immunology, Department of Pediatrics, University of Minnesota 1979-1980.

Certification: Pediatrics, 1980.


View PubMed Publications


Gene Therapy for SCID-X1 Using Self-Inactivating Gamma. Principal Investigator. National Institutes of Health. Sep 2010-Aug 2015. #U01 AI 087628.

Rare Diseases Clinical Consortia for the Rare Diseases. Principal Investigator. National Institutes of Health. Sep 2009-Aug 2014. #U54 AI 082973.

Hypoxia and potassium channel activity in T Lymphocytes. Principal Investigator. National Institutes of Health. Jun 2009-Jun 2014. #R01 CA 095286.