Bryan H. Goldstein, MD

Attending Cardiologist, Cardiac Catherization Laboratory

Assistant Professor, UC Department of Pediatrics

Phone 513-636-7072

Fax 513-636-2410

Email bryan.goldstein@cchmc.org

Clinical

Cardiac catheterization; intervention for congenital heart disease; transcatheter valve implantation; single ventricle physiology

Research

Congenital heart disease outcomes research; novel transcatheter interventions (including hybrid therapies); single ventricle physiology (including Fontan); vascular endothelial function; ventricular mechanics and diastolic function; renal injury in congenital heart disease

Bryan H. Goldstein, MD, joined the Heart Institute in 2011 in the section of Cardiac Catheterization and Intervention. A native of Boston, Mass., Dr. Goldstein graduated with honors from Amherst College, where he was a goalie on the men's lacrosse team. He earned his medical degree with honors from Boston University School of Medicine. He completed his pediatric residency at Children's Hospital Boston (BCRP) and his pediatric and interventional cardiology fellowships at the University of Michigan (C.S. Mott Children's Hospital) in Ann Arbor.

Dr. Goldstein’s clinical expertise is in congenital cardiac catheterization. He is interested in invasive physiologic assessment of complex congenital heart disease (CHD), including single ventricle physiology, as well as minimally invasive transcatheter therapies. Dr. Goldstein has particular clinical interests in transcatheter valve therapy and innovative hybrid therapies

Dr. Goldstein’s research interests include novel transcatheter interventions and long-term outcomes following interventions for CHD. An additional research focus includes long-term functional outcomes in Fontan survivors, including investigations of vascular function and ventricular diastolic function in the Fontan population. Dr. Goldstein receives grant funding from the American Heart Association and NHLBI. He is a co-investigator for the Nit-Occlud® PDA Post-Approval Study and previously served as a co-investigator for the Melody™ Transcatheter Pulmonary Valve Post-Approval Study.

Dr. Goldstein is a fellow of the American College of Cardiology (FACC), the Society of Cardiovascular Angiography and Interventions (FSCAI), and the American Academy of Pediatrics (FAAP) and an active member of the American Heart Association (AHA). He received the Pediatric Interventional Cardiology Symposium Young Leadership Award in 2013 and was recently honored with election to the Emerging Leader Mentorship program 2015-2017 through SCAI, ACC and CRF.

MD: Boston University School of Medicine, Boston, MA, 2004.

Residency: Pediatrics, Children’s Hospital Boston, Boston, MA, 2007. 

Fellowship: Pediatric Cardiology, C.S. Mott Children’s Hospital, Ann Arbor, MI, 2010.

Advanced Fellowship: Interventional Cardiology, C.S. Mott Children’s Hospital, Ann Arbor, MI, 2011.

Certifications: Pediatrics, 2007; Pediatric Cardiology, 2010. 

View PubMed Publications

Lin H, Desai S, Nicolas R, Guavreau K, Foerster S, Sharma A, Armsby L, Odegard K DiNardo J, Vincent J, El-Said H, Goldstein BH, Holzer R, Balzer D, Bergersen L. Sedation and Anesthesia Related Adverse Events in Pediatric and Congenital Cardiac Catheterization. Pediatr Cardiol. 2015.

Seckeler M, Hirsch R, Beekman RH III, Goldstein BH. A New Predictive Equation for Oxygen Consumption in Children and Adults with Congenital and Acquired Heart Disease. Heart. 2015 Apr 1;101(7)517-24.

Karani KB, Zafar F, Morales DLS, Goldstein BH. Hybrid Stage I Palliation in a 1.1 Kilogram 28 Week Preterm Neonate with Posterior Malalignment Ventricular Septal Defect, Left Ventricular Outflow Tract Obstruction and Coarctation of the Aorta. World J Pediatr Congenit Heart Surg. 2014 Oct;5(4):603-7.

Zampi JD, Hirsch-Romano JC, Goldstein BH, Shaya JA, Armstrong AK. Hybrid Approach for Pulmonary Atresia with Intact Ventricular Septum: Early Single Center Results and Comparison to the Standard Surgical Approach. Catheter Cardiovasc Inter. 2014 Apr 1;83(5):753-61.

Zampi JD, Hirsch JC, Goldstein BH, Armstrong AK. Use of a Pressure Guidewire to Assess Pulmonary Artery Band Adequacy in the Hybrid Stage I Procedure for High Risk Neonates with Hypoplastic Left Heart Syndrome and Variants. Congenit Heart Dis. 2013 Mar-Apr;8(2):149-58.

Goldstein BH, Hirsch R, Zussman M, Vincent JA, Torres A, Coulson J, Ringel RE, Beekman RH III. Percutaneous Balloon-Expandable Covered Stent Implantation for Treatment of Traumatic Aortic Injury in Children and Adolescents. Am J Cardiol. 2012 Nov 15;110(10):1541-5.

Goldstein BH, Golbus JR, Sandelin AM, Warnke N, Gooding L, King KK, Donohue JE, Yu S, Gurney JG, Goldberg CS, Rocchini AP, Charpie JR.  Impact of Vitamin C on Endothelial Function and Exercise Capacity in Patients with a Fontan Circulation. Congenit Heart Dis. 2011.

Goldstein BH, Fifer CG, Armstrong AK, Gelehrter SK, Treadwell MC, van de Ven C, Rocchini AP. Use of a Pressure Guidewire in Fetal Cardiac Intervention for Critical Aortic Stenosis. Pediatrics. 2011 Aug 15.

Goldstein BH, Golbus JR, Sandelin AM, Warnke N, Gooding L, King KK, Donohue JE, Gurney JG, Goldberg CS, Rocchini AP, Charpie JR. Usefulness of Peripheral Vascular Function to Predict Functional Health Status in Patients with a Fontan Circulation. Am J Cardiol. 2011 Aug 1;108(3):428-34.

Goldstein BH, Connor C, Gooding L, Rocchini AP. Relation of Systemic Venous Return, Diastolic Dysfunction and Pulmonary Vascular Resistance to Exercise Capacity in Patients with Single Ventricle Receiving Fontan Palliation. Am J Cardiol. 2010 Apr 15;105(8):1169-75.

Utilizing Vascular Function to Predict Functional Outcomes in Fontan Survivors. Principal Investigator. American Heart Association. Jan 2014-Dec 2015.

PFM NitOcclud Post Approval Study. Co-Investigator. PFM Medical. Jun 2015-Jun 2017.

A Phase I/II Dose Escalation Trial of Udenafil in Adolescents with Single Ventricle Physiology after Fontan Palliation. Co-Investigator. National Heart, Lung, and Blood Institute. Jul 2014-Jul 2015.

Off-label Use of the Melody Valve in the “Native” Right Ventricular Outflow Tract. Co-Investigator. National Heart, Lung, and Blood Institute. Jul 2014-Dec 2015.