Stuart Handwerger, MD

Professor, UC Department of Pediatrics

Phone 513-636-4209

Fax 513-636-7486

Email stuart.handwerger@cchmc.org

Regulation of gene expression in human placenta and uterine decidua during differentiation.

Visit the Handwerger Lab.

MD: University of Maryland School of Medicine, Baltimore, MD, 1964.

Residency: Mt. Sinai Hospital, New York, NY, 1965 to 1966.

Fellowship: Harvard Medical School, Children's Hospital Medical Center, Boston, MA, 1968 to 1969.

Certification: Diplomate, American Board of Pediatrics, 1969; Subspecialty Boards, Pediatric Endocrinology, 1978.

Handwerger S, Brar A. Paracrine/autocrine regulation of human placental lactogen gene. Biology of the Neonate. 2014.

Kessler CA, Stringer, Stanek J, Stringer K, Handwerger S. ETS1 induces human trophoblast differentiation. Endocrinology. 2014.

Sheridan R, Belundi C, Khoury J, Stanek J, Handwerger S. FOXO1 expression in villous trophoblast of preeclampsia and fetal growth restriction placentas. Histol Histpathol. 2014 Sept 9.

Xie H, Sun X, Piao Y, Jegga AG, Handwerger S, Ko MS, Dey SK. Silencing or amplification of endocannabinoid signaling in blastocysts via CB1 compromises trophoblast cell migration. J Biol Chem. 2012 Sep 14;287(38):32288-97.

Sheridan RM, Stanek J, Khoury J, Handwerger S. Abnormal expression of transcription factor AP-2α in pathologic placentas. Human Pathology. 2012 Nov;43(11):1866-74.

Schroeder J, Stanek J, Handwerger S. TEAD1 inhibits prolactin gene expression in cultured human uterine decidual cells. Molecular and Cellular Endocrinology. 2011;295:32-38.

Schroeder J, Kessler C, Handwerger S. TWIST1 markedly represses the decidualization of human uterine stromal cells. Endocrinology. 2011;152:4368-76.

Sherafat-Kazemzadeh R, Schroeder JK, Kessler CA, Handwerger S. Parathyroid Hormone-Like Hormone (PTHLH) Represses Decidualization of Human Uterine Fibroblast Cells by an Autocrine/Paracrine Mechanism. J. Clin. Endicrinol. Metab. 2010;96:102-25.

Tang M, Naidu D, Hearing P, Handwerger S, Tabibzadeh S. LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal differentiation: a novel autocrine role. Endocrinology. 2010;151:1320-30.

Handwerger S. New insights into the regulation of human cytotrophoblast cell differentiation Molecular and Cellular Endocrinology. Molecular and Cellular Endocrinology. 2010;323:94-104.