Biographies

E-mail this page

(All fields required)

Recipient's email address

Please enter a valid email.

Your name

Please enter your name.

Your email address

Please enter a valid email.

Find another Doctor or Researcher

High Res

Catherine Dent Krawczeski, MD

Director, Quality Improvement & Clinical Effectiveness

Co-Director, Center for Acute Care Nephrology

Associate Professor, UC Department of Pediatrics

Phone: 513-801-1801

Fax: 513-636-3952

Email: catherine.krawczeski@cchmc.org

Show All

Specialties

Clinical Interests

Cardiac intensive care; heart failure; heart transplantation; pulmonary hypertension; single ventricle physiology

Research Interests

Acute kidney injury after cardiopulmonary bypass; urinary biomarkers of renal ischemia; intensive care outcomes; cardiopulmonary bypass mediated injury

Biography

Catherine Krawczeski MD is an associate professor of pediatrics with the University of Cincinnati College of Medicine and is clinical faculty in the Cardiac Intensive Care Unit. She is the director of Quality Improvement and Clinical Effectiveness for the Heart Institute and a co-director of the Center for Acute Care Nephrology.

Dr. Krawczeski received her medical degree from the University of Missouri and completed pediatric residency at Washington University/St. Louis Children’s Hospital and fellowships in pediatric cardiology and pediatric critical care medicine at the same institution. She is board certified in both specialties. Dr. Krawczeski has been on staff at Cincinnati Children’s Hospital since 2001.

Dr. Krawczeski focuses her research on clinical outcomes after pediatric cardiac surgery. She has a particular interest in the effects of cardiopulmonary bypass on the kidney. She has had a close collaboration with Prasad Devarajan, director of the division of Nephrology, translating biomarker technology to the bedside for early diagnosis of acute kidney injury (AKI) after cardiopulmonary bypass. Their successful discovery and validation of early AKI biomarkers, such as NGAL, has set the stage for future studies of potential therapeutic interventions. This collaboration has been further strengthened by the recent creation of the Center for Acute Care Nephrology (CACN), a joint effort by the Heart Institute and the division of Nephrology for the purpose of coordinating clinical care and AKI translational and clinical research.

Dr. Krawczeski also has an interest in Quality Improvement. She has been instrumental in creating Heart Institute “dashboards” to track outcomes and determine strategic improvement priorities. She collaborates closely with the Anderson Center to facilitate improvement initiatives within the Heart Institute.

Education and Training

MD: University of Missouri, Kansas City, Missouri, 1991.

Residency: Washington University, St. Louis Children's Hospital, St. Louis, Missouri.

Fellowships: Washington University, St. Louis Children's Hospital, St. Louis, Missouri.

Certification: American Board of Pediatrics 1995, recertification 2002; American Board of Pediatrics, Sub-board of Pediatric Critical Care 2000, recertification 2007; American Board of Pediatrics, Sub-board of Pediatric Cardiology 2002.

Publications

View PubMed Publications

Krawczeski CD, Goldstein SL, Woo, JG, Wang Y, Piyaphanee N, Ma Q, Bennett M, Devarajan P. Temporal relationship and predictive value of urinary acute kidney injury biomarkers after pediatric cardiopulmonary bypass. J Am Coll Cardiol. 2011 Nov 22;58(22):2301-2309.

Zappitelli M, Krawczeski C, Devarajan P, Wang Z, Sint K, Thiessen-Philbrook H, Li S, Bennett M, Ma Q, Shlipak M, Garg A, Parikh C for the TRIBE-AKI Consortium. Early post-operative serum cystatin C predicts severe AKI after pediatric cardiac surgery: a multi-center prospective study. Kidney International. 2011, Sept;80:6555-662.

Parikh CR, Coca SG, Devarajan P, Shlipak MG, Thiessen-Philbrook H, Edelstein CL, Wang Z, Zappitelli M, Koyner J, Krawczeski CD, Patel UD, Swaminathan M, Passik CS, Garg AX; for the TRIBE-AKI Consortium. Post-operative biomarkers predict acute kidney injury and poor outcomes after cardiac surgery. J Am Soc Nephr. 2011, Sept;22:1748-1757.

Parikh CR, Devarajan P, Zappitelli M, Sint K, Thiessen-Philbrook H, Li S, Kim R, Koyner J, Coca SG, Edelstein CL, Shlipak MG, Garg AX, Krawczeski CD; for the TRIBE-AKI Consortium. Early post-operative urine and serum biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery. J Am Soc Nephr. 2011, Sept;22:1737-1747.

Krawczeski CD, Woo JG, Wang Y, Bennett MR, Ma Q, Devarajan P. Neutrophil gelatinase-associated lipocalin concentrations predict development of acute kidney injury in neonates and children after cardiopulmonary bypass. J Pediatr. 2011 Jun;158(6):1009-1015.e1

Haase M, Devarajan P, Haase-Fielitz A, Bellomo R, Cruz DN, Wagener G, Krawczeski CD, Koyner JL, Murray J, Zappitelli M, Goldstein SL, Makris K, Ronco C, Martensson J, Marthing C-R, Venge P, Siew E, Ware LB, Ikizler A, Mertens PR. The outcome of neutrophil gelatinase-associated lipocalin (NGAL)-positive subclinical acute kidney injury: A multi-center pooled analysis of prospective studies. J Am Coll Cardio. 2011 Apr;57:1752-1761

Krawczeski CD, Vandevoorde RG, Kathman T, Bennett MR, Woo JG, Wang Y, Griffiths RE, Devarajan P. Serum cystatin C is an early predictive biomarker of acute kidney injury after pediatric cardiopulmonary bypass. Clin J Am Soc Nephrol. 2010 Sep;5(9):1552-7.

Ohye RG, Sleeper LA, Mahony L, Newburger JW, Pearson GD, Lu M, Goldberg CS, Tabbutt S, Frommelt FC, Ghanayem NS, Laussen PC, Rhodes JF, Lewis AB, Mital S, Ravishankar C, Williams IA, Dunbar-Masterson C, Atz AM, Colan S, Minich LL, Pizarro, C, Kanter KR, Jaggars J, Jacobs J, Krawczeski CD, Pike N, McCrindle BW, Virzi L, Gaynor JW; for the Pediatric Heart Network Investigators. Outcomes of the Norwood procedure in infants randomized to a modified Blalock-Taussig versus right ventricle-to-pulmonary artery shunt. New Engl J Med. 2010 May;362:1980-92.

Dent CL, Ma Q, Dastrala S, Bennett M, Mistnefes M, Barasch J, Devarajan P. Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity, and mortality after cardiac surgery: a prospective study. Criti Care. 2007 Dec;11(6):R127

Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imagining abnormalities following the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovas Surg. 2006 Jan;131(1):190-197.

Grants

Biomarkers of renal injury in cardiac surgery. Co-Investigator. National Heart, Lung, and Blood Institute. Jul 2007 - Jun 2012.

Phase II/III double blind, randomized, placebo controlled, clinical trial to determine the safety and efficacy of intravenous L-citrulline versus placebo in children undergoing cardiopulmonary bypass. Primary Investigator. Asklepion Pharmaceuticals. Feb 2008 - Dec 2012.

Progression of acute kidney injury to chronic kidney disease. Co-Investigator. National Institutes of Health. Jan 2009 - Dec 2013.

Outcomes after single ventricle reconstruction in children with hypoplastic left heart syndrome and other single right ventricle anomalies. Primary Investigator. National Institutes of Health. Jun 2008 - Dec 2015.