A photo of Theodosia Kalfa.

Theodosia A. Kalfa, MD, PhD


  • Co-Director, Erythrocyte Diagnostic Laboratory
  • Professor, UC Department of Pediatrics

About

MD: Aristotle University Medical School, Thessaloniki, Greece, 1990.

PhD: Aristotle University Medical School, Thessaloniki, Greece, 1997.

Residency: University Of North Carolina, Chapel Hill, NC, 1999.

Fellowship: Duke University Medical Center, Durham, NC, 2003.

Certification: Hematology / oncology, American Board of Pediatrics, 2004; Pediatrics, American Board of Pediatrics, 2000; ECFMG Certification, 1995.

Licenses: Full and unrestricted medical license (OH Medical Board), 2003-present; full and unrestricted license of medical practice in Greece, 1990-present.

Interests

Signaling in erythrocytes; erythropoiesis; sickle cell disease; reactive oxygen species

Additional Languages

Greek

Insurance Information

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Publications

Selected

VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. Seu, KG; Trump, LR; Emberesh, S; Lorsbach, RB; Johnson, C; Meznarich, J; Underhill, HR; Chou, ST; Sakthivel, H; Nassar, NN; Seu, KJ; Blanc, L; Zhang, W; Lutzko, CM; Kalfa, TA. American Journal of Human Genetics. 2020; 107(6):1149-1156.

Selected

Red cell membrane disorders: structure meets function. Risinger, M; Kalfa, TA. Blood. 2020; 136(11):1250-1261.

Selected

Signaling and cytoskeletal requirements in erythroblast enucleation. Konstantinidis, DG; Pushkaran, S; Johnson, JF; Cancelas, JA; Manganaris, S; Harris, CE; Williams, DA; Zheng, Y; Kalfa, TA. Blood. 2012; 119(25):6118-6127.

A proposed path to explaining the unexplained anemia of aging. El Kassar, N; Dezern, AE; Abkowitz, J; Artz, A; Beerman, I; Bolton, K; Brooks, MM; Borate, U; Ershler, WB; Ganz, T; White, KE; Zhang, D; Ferrucci, L; Kuchel, GA. The journals of gerontology. Series A, Biological sciences and medical sciences. 2026; 81(1).

Longitudinal changes in haemoglobin, iron stores, and inflammatory markers following surgery and in critical illness: an analysis from the Practical Anaemia Bundle for Sustained Blood Recovery randomised clinical trial. Warner, MA; Hanson, AC; Johnson, ML; Go, RS; Gajic, O; Schulte, PJ; Kor, DJ; Serra, M; Kalfa, TA; Blanc, L. British Journal of Anaesthesia. 2025.

Molecular surprises in evaluations of red cell disorders. Elgammal, Y; Zhang, W; Kalfa, TA. Hematology. American Society of Hematology. Education Program. 2025; 2025(1):370-376.

When a Trait Becomes a Disease: A Rare Hematologic Overlap of Sickle Cell Trait and Hereditary Spherocytosis. Ammari, O; Shah, M; Elgammal, Y; Husami, A; Kalfa, TA; Gollamudi, J. American Journal of Hematology. 2025.

The diagnosis and treatment of red cell membrane disorders: algorithm for the general hematologist. Kalfa, TA. Clinical Advances in Hematology and Oncology. 2025; 23(9):534-538.

Transcriptomic analysis uncovers hidden intronic and synonymous pathogenic variants in red cell membrane disorders. Zhang, W; Elgammal, Y; Husami, A; Voulgaridou, A; Sakthivel, H; Cannon, M; Bonavita, L; Grimley, M; Heeney, M; Ntoumaziou, A; Risinger, M; Yang, E; Kalfa, T. Blood. 2025; 146(Supplement 1):282-282.

Imaging flow cytometry for detection of red blood cell inclusions: A quantitative approach to assess splenic filtration function in sickle cell disease. Rios, CR; Lu, M; Hanson, K; Savidge, E; Ward, T; Korpik, J; Reynaud, M; Ware, R; Kalfa, T; Quinn, C. Blood. 2025; 146(Supplement 1):1188.

From the Blog

Blood Cell Production Discovery Opens Path to Improve Anemia of Inflammation
Tools for Science

Blood Cell Production Discovery Opens Path to Improve Anemia of Inflammation

Theodosia A. Kalfa, MD, PhD10/31/2022

Rare Disease Day: More Tools for Solving Diagnostic Mysteries
Rare Diseases

Rare Disease Day: More Tools for Solving Diagnostic Mysteries

Theodosia A. Kalfa, MD, PhD3/1/2021

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