Carolyn M. Lutzko, PhD

Associate Professor, UC Department of Pediatrics

Phone 513-803-3420

Fax 513-636-1146

Email carolyn.lutzko@cchmc.org

Regulating human pluripotent stem cell; somatic cell reprogramming in iPSC; human embryonic stem cell physiology and differentiation; hESC; Cystic Fibrosis

BA: University of Guelph, S.Sc. Hon, Molecular Biology and Genetics Guelph, Ontario, Canada 1992.

PhD: University of Toronto, PhD Department of Laboratory Medicine Toronto, Ontario, Canada 1999.

Fellowship: Childrens Hospital Los Angeles Department of Pediatrics Division of Research Immunology/BMT Los Angeles, California 1999-2002.

Mishra S, Wang X, Smiley N, Bui KC, Senadheera D, Chang D, Lutzko C. In utero delivery of lentiviral supernatant to the amniotic fluid genetically modifies airway epithelial progenitors. American Journal of Respiratory Cellular and Molecular Biology. 2010.

Bui KC, Senadheera D, Wang X, Hendrickson B, Friedlich P, Lutzko C. Isolation of progenitors from the peripheral blood of patients with acute respiratory or cardiac failure who required ECMO support. American Journal of Respiratory and Critical Care Medicine. 2010 181:226-237.

Harb R, Xie G, Lutzko C, Guo Y, Wang X, Hill CK, Kanel GC, DeLeve LD. Bone marrow progenitor cells repair rat hepatic sinusoidal endothelial cells after liver injury. Gastroenterology. 2009  137:704-12.

Chang D, Tsai S, Wang X, Xia P, Senadheera D, Lutzko C. Molecular characterization of the human nanog protein. Stem Cells. 2009 27:812-821.

Jiang X, Gwye Y, Lutzko C, Lawlor ER. Isolation and characterization of neural crest stem cells derived from in vitro – differentiated human embryonic stem cells. Stem Cells and Development. 2009 18:259-270.

Melchior K, Weib J, Zaehres H, Yong-Mi K, Lutzko C, Roosta N, Hescheler J, Muschen M. The WNT receptor FZD7 contributes to self-renewal of signaling of human embryonic stem cells. Journal of Biological Chemistry. 2008 389:897-903.

Liebler J, Lutzko C, Banfalvi A, Senadheera D, Crandall ED, Borok Z. Retention of human bone marrow-derived cells in murine lungs following bleomycin injury. American Journal of Pathology-Lung and Cellular Molecular Physiology. 2008 295:285-292.

Rodriguez RT, Velkey JM, Lutzko C, Seerke R, Kohn DB, O’Shea KS, Firpo MT. Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types. Journal of Experimental Biology & Medicine. 2007 232:1368-80.

Hendrickson B, Senadheera D, Mishra S, Bui KC, Wang XC, Chan B, Petersen, D, Pepper K, Lutzko C. Development of lentiviral vectors with regulated respiratory epithelia expression in vivo. American Journal of Respiratory Cellular and Molecular Biology. 2007 37:414-23.