Clinical Interests

Cardiac anesthesia; neonatal anesthesia

Research Interests

Anesthesia on the developing brain

MD: McGill University, Montreal, Canada, 1977.

Residency: Anesthesiology, Brigham and Women's Hospital, Boston, MA, 1982-84; Pediatrics, University of Minnesota, Minneapolis, MN, 1981-82; Pediatrics, University of Minnesota, Minneapolis, MN, 1978-79.

Fellowship: Pediatric Anesthesiology, Children's Hospital Medical Center, Boston, MA, 1984-85.

Certification: Pediatrics, 1984; Anesthesiology, 1985.

Istaphanous GK, Howard J, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW. Comparison of the Neuroapoptotic Properties of Equipotent Anesthetic Concentrations of Desflurane, Isoflurane, or Sevoflurane in Neonatal Mice. Anesthesiology. 2011 Feb 2.

McAuliffe JJ, Bronson SL, Hester MS, Murphy BL, Dahlquist-Topalá R, Richards DA, Danzer SC. Altered patterning of dentate granule cell mossy fiber inputs onto CA3 pyramidal cells in limbic epilepsy. Hippocampus. 2011 Jan;21(1):93-107.

McAuliffe JJ, Loepke AW, Miles L, Joseph B, Hughes E, Vorhees CV. Desflurane, isoflurane, and sevoflurane provide limited neuroprotection against neonatal hypoxia-ischemia in a delayed preconditioning paradigm.Anesthesiology. 2009 Sep;111(3):533-46.

Loepke AW, Istaphanous GK, McAuliffe JJ 3rd, Miles L, Hughes EA, McCann JC, Harlow KE, Kurth CD, Williams MT, Vorhees CV, Danzer SC. The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory.Anesth Analg. 2009 Jan;108(1):90-104.

McAuliffe JJ, Joseph B, Hughes E, Miles L, Vorhees CV. Metallothionein I,II deficient mice do not exhibit significantly worse long-term behavioral outcomes following neonatal hypoxia-ischemia: MT-I,II deficient mice have inherent behavioral impairments.Brain Res. 2008 Jan 23;1190:175-85.

McAuliffe JJ, Joseph B, Vorhees CV. Isoflurane-delayed preconditioning reduces immediate mortality and improves striatal function in adult mice after neonatal hypoxia-ischemia.Anesth Analg. 2007 May;104(5):1066-77, tables of contents.

Gunter JB, McAuliffe JJ, Beckman EC, Wittkugel EP, Spaeth JP, Varughese AM. A factorial study of ondansetron, metoclopramide, and dexamethasone for emesis prophylaxis after adenotonsillectomy in children. Paediatr Anaesth. 2006 Nov;16(11):1153-65.

McAuliffe JJ, Miles L, Vorhees CV. Adult neurological function following neonatal hypoxia-ischemia in a mouse model of the term neonate: water maze performance is dependent on separable cognitive and motor components.Brain Res. 2006 Nov 6;1118(1):208-21.

Loepke AW, McCann JC, Kurth CD, McAuliffe JJ. The physiologic effects of isoflurane anesthesia in neonatal mice. Anesth Analg. 2006 Jan;102(1):75-80.

Gunter JB, McAuliffe JJ, Gregg T, Weidner NJ, Varughese AM, Sweeney, DM. Continuous epidural butophanol relieves pruritus associated with epidural morphine infusioins in children. Paediatric Anaesthesia. 2000 10(2):167-172.