Biographies

Satish K. Madala, PhD

Assistant Professor, UC Department of Pediatrics

Phone: 513-636-9852

Email: satish.madala@cchmc.org

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Specialties

Visit the Madala Lab.

Biography

Dr. Madala’s research interests are to identify the cellular and molecular mechanisms involved the initiation, maintenance, and progression of pulmonary fibrosis. His lab’s research tools include using molecular, biochemical and immunology methods to identify novel therapeutic targets in chronic lung diseases such as idiopathic pulmonary fibrosis (IPF) and systemic sclerosis (SSc), and cystic fibrosis (CF). The lab’s early studies using several mouse models of fibrosis have revealed that multiple growth factors contribute to the deposition of collagen and other extracellular matrix (ECM) proteins in the lung.  The lab’s recent studies have helped to define unique functions of fibrocytes and their heterogeneous interactions with other lung stromal cells in causing the expansion of adventitial and pleural fibrotic lesions in the lung.

Education and Training

Postdoctoral training: Wynn Lab, Immunopathogenesis Section, LPD, NIAD, NIH, Bethesda, MD.

PhD: National Institute of Nutrition, Osmania University, Hyderabad, India.

Publications

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Grants

Role of TGFα-induced fibrocytes in pulmonary fibrosis and pulmonary hypertension. Principal Investigator. American Heart Association NCRP Scientist Development Grant. Jan 2012- Dec 2015.

Role of IL-31 in immunopathology of Systemic sclerosis (SSc). Principal Investigator. Bristol-Myers Squibb preclinical contract. 2013- 2016. R03 NIAMS.

Molecular Mechanisms of Pulmonary Fibrosis. Principal Investigator. Parker B. Francis Fellowship. 2013 - Dec 2016.