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High Res

Sean R. Moore, MS, MD

Assistant Professor, UC Department of Pediatrics

Phone: 513-636-4464

Fax: 513-636-7805

Email: sean.moore@cchmc.org

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Specialties

Clinical Interests

General gastroenterology; inflammatory bowel diseases

Research Interests

Diarrheal diseases; glutamine; global health

Biography

The Gastroenterology, Hepatology and Nutrition laboratory is broadly interested in the reciprocal cycle of childhood diarrhea and malnutrition, with a current focus on the mechanisms of a promising glutamine-based oral rehydration and nutrition therapy. Using cellular and molecular techniques in both cell culture and an infant mouse model of undernutrition, we study the role of EGFR -- a key regulator of intestinal homeostasis -- in glutamine’s benefits for intestinal health.

In addition, we participate in epidemiologic studies of early childhood diarrhea and undernutrition with colleagues at the Federal University of Ceará in Fortaleza, Brazil and the University of Virginia.

Education and Training

BA: Chemistry & Biology, Asbury College, Wilmore, KY.

MS: Epidemiology, University of Virginia, Charlottesville, VA.

MD: Johns Hopkins, Baltimore, MD, 2003.

Residency: Vanderbilt University, Nashville, TN, 2006.

Fellowship: Vanderbilt University, Nashville, TN 2009.

Certification: Pediatrics, 2006.

Publications

View PubMed Publications

Moore SR. Update on prolonged and persistent diarrhea in children. Curr Opin Gastroenterol. 2010 Sep 10.

Moore SR, Lima NL, Soares AM, Oriá RB, Pinkerton RC, Barrett LJ, Guerrant RL, Lima AA. Prolonged episodes of acute diarrhea reduce growth and increase risk of persistent diarrhea in children. Gastroenterology. 2010 Oct;139(4):1156-64.

Guerrant RL, Oriá RB, Moore SR, Oriá MOB, Lima AA. Malnutrition as an enteric infectious disease, with long-term effects on child development. Nutr Rev. 2008;66(9):487-505.

Checkley W, Buckley G, Gilman RH, Assis AM, Guerrant RL, Morris SS, Mølbak K, Valentiner-Branth P, Lanata CF, Black RE. Multi-country analysis of the effects of diarrhoea on childhood stunting. Int J Epidemiol. 2008;37(4):816-30.

Moore SR, Lorntz B, Lima AA, Guerrant RL. Risk factors for adverse outcomes in developing countries. Lancet. 2007;369(9564):824-5.