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John P. Pestian, PhD, MBA

Director, Computational Medicine Center

Professor, UC Department of Pediatrics

Phone 513-636-1627

Fax 513-636-2056


The founding director of the Division of Biomedical Informatics, Dr. Pestian now focuses on directing and developing the Computational Medicine Center (CMC). The CMC was established in 2003 by a $28 million grant from Ohio's Third Frontier Project.

Dr. Pestian's research lab is focused on using the science of natural language understanding in biomedical settings. Along with a growing list of collaborators, lab members focus on developing and implementing neuro-cognitive algorithms that enable computers to understand the concepts and semantic relationships within clinical text

BS: St. Francis College, Loreto, PA, 1981.

MA: University of Steubenville, Steubenville, OH, 1987.

PhD: Virginia Commonwealth University, Richmond, VA, 1994.

View PubMed Publications

Pestian J. A conversation with Edwin Shneidman. Suicide Life Threat Behav. 2010 Oct;40(5):516-23.

Pestian J, Spencer M, Matykiewicz P, Zhang K, Vinks AA, Glauser T. Personalizing Drug Selection Using Advanced Clinical Decision Support. Biomed Inform Insights. 2009 Jun 23;2:19-29.

Demner-Fushman D, Ananiadou S, Cohen KB, Pestian J, Tsujii J, Webber B. Themes in biomedical natural language processing: BioNLP08. BMC Bioinformatics. 2008 Nov 19;9 Suppl 11:S1.

Pestian JP, Matykiewicz P, Grupp-Phelan J, Lavanier SA, Combs J, Kowatch R. Using natural language processing to classify suicide notes. AMIA Annu Symp Proc. 2008 Nov 6:1091.

Duch W, Matykiewicz P, Pestian J. Neurolinguistic approach to natural language processing with applications to medical text analysis. Neural Netw. 2008 Dec;21(10):1500-10.

Matykiewicz P, Pestian J, Duch W, Johnson N. Unambiguous concept mapping in radiology reports: graphs of consistent concepts. AMIA Annu Symp Proc. 2006:1024.

Wade SL, Wolfe C, Brown TM, Pestian JP. Putting the pieces together: preliminary efficacy of a web-based family intervention for children with traumatic brain injury. J Pediatr Psychol. 2005 Jul-Aug;30(5):437-42.

Wade SL, Wolfe CR, Pestian JP. A web-based family problem-solving intervention for families of children with traumatic brain injury. Behav Res Methods Instrum Comput. 2004 May;36(2):261-9.

Siegel RM, Kiely M, Bien JP, Joseph EC, Davis JB, Mendel SG, Pestian JP, DeWitt TG. Treatment of otitis media with observation and a safety-net antibiotic prescription. Pediatrics. 2003 Sep;112(3 Pt 1):527-31.

Jegga AG, Sherwood SP, Carman JW, Pinski AT, Phillips JL, Pestian JP, Aronow BJ. Detection and visualization of compositionally similar cis-regulatory element clusters in orthologous and coordinately controlled genes. Genome Res. 2002 Sep;12(9):1408-17.