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High Res

Manoj K. Pandey, PhD

Instructor, UC Department of Pediatrics

Phone: 513-803-1694

Email: manoj.pandey@cchmc.org

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Specialties

Clinical

Immunology

Research

Lipid arbitrated antibodies and cytokines comebacks in several Lysosomal diseases.

Biography

Manoj Kumar Pandey is a scientist in the Division of Human Genetics at Cincinnati Children's Hospital and Medical Research Center. Dr. Pandey earned his PhD in the topic “Maternal Immunoregulation and Fetal Survival” from the Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, India. He completed his Post-Doctoral Trainings from Mayo Clinic, Rochester, MN and Cincinnati Children’s Hospital and Medical Research Center, Cincinnati, OH. Dr. Pandey has presented and published his research outcomes in various national and international sessions and reputed peer-reviewed medical and scientific journals. He is a member of the American Association of Immunology, the American Association for the Advancement of Science, the International Society of Complement and the Mayo Clinic Alumni Association. The mainstream of Dr. Pandey’s research is based on the characterization of various immunological cells as well as their effector functions for persuading inflammation in illnesses like immune complex mediated diseases, asthma, cancer, recurrent spontaneous abortion and Gaucher diseases.

Education and Training

MS: CSJM University, India, 1995.

PhD: Sanjay Gandhi Post Graduate Institute of Medical Sciences, India, 2003.

Post Doc: Mayo Clinic, Rochester, MN, 2004.

Post Doc: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2008.

Publications

Pandey MK, Agrawal S. Induction of MLR-Bf and protection of fetal loss: A current double blind randomized trial of paternal lymphocyte immunization for women with recurrent spontaneous abortion. International immunopharmacology. 2004,2: 289-298.

Pandey MK, Thakur S, Agrawal S. Lymphocyte immunotherapy and its probable mechanism in the maintenance of pregnancy in women with recurrent spontaneous abortion. Arch Gynecol Obstet. 2004, 269:161–172.

Pandey MK, Rani Reena, Agrawal S. An update in recurrent spontaneous abortion. Arch Gynecol Obstet. 2005, 272 :95-108.

Pandey M, Iankov ID, Harvey M, Griesmann GE, Federspiel MJ, Russell SJ. Immunoglobulin g antibody-mediated enhancement of measles virus infection can bypass the protective antiviral immune response. J Virol. 2006, 80(17):8530-8540.

Kohl J, Balder R, Lewkowish I, Pandey MK, Hawlisch H, Wang L, Herman N, Best J, Zwirner J, Whitsett JA, Lambns JD, Paul R, Schmitz-Perreira S, Scharfstein J, Wills-Karp M. A regulatory role for the C5a anaphylatoxin on type 2 immunity in asthma. J Clin Invest. 2006,16 (3):783-796.

Jongerius I, Köhl J, Pandey MK, Ruyken M, Van Kessel KPM, Van Strijp JAG, Rooijakkers SHM. Staphylococcal complement evasion by various convertase-blocking molecules. The Journal of Experimental Medicine. 2007, 204(10) 2461-2471.

Bestebroer J, Aerts PC, Rooijakkers SH, Pandey MK, Köhl J, van Strijp JA, de Haas CJ. Functional basis for complement evasion by staphylococcal superantigen-like7. Cellular Microbiology. (2010) 12(10), 1506–1516

Fritsche LG, Lauer N, Hartmann A, Stippa S, Keilhauer CN, Oppermann M, Pandey MK, Köhl J, Zipfel PF, Weber BH, Skerka C. An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD). Human Molecular Genetics. 2010 1–11.

Weaver DJ , Reis ES, Pandey MK, Köhl G, Harris N, Gerard C, Köhl J. C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells. Eur. J. Immunol. 2010, 40, 1.

Schmudde I, Laumonnier Y, Pandey MK, Clark JR, König P, Gerard NP, Gerard C, Wills-Karp M, Köhl J, Zhang X. A Critical Role for C5L2 in the Pathogenesis of Experimental Allergic Asthma. J Immunol. 2010; 185;6741-6752.