Michael J. Rosen, MD, MSCI

Attending Physician, Division of Gastroenterology, Hepatology and Nutrition

Physician, Schubert-Martin Inflammatory Bowel Disease Center

Assistant Professor, UC Department of Pediatrics

Phone: 513-803-7044


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Inflammatory bowel disease


Inflammatory bowel disease; intestinal mucosal immunology


Michael J. Rosen, MD, MSCI, focuses his career on the clinical care of children with inflammatory bowel disease (IBD), and to research aimed at better understanding the causes of chronic inflammation in childhood IBD. The primary focus of Dr. Rosen's laboratory is on the contribution of Type 2 (Th2) inflammation to pediatric colitis.  Studies from Dr. Rosen’s lab have demonstrated increased mucosal activation of STAT6, a key Th2 cellular signaling protein, in children with ulcerative colitis and shown a role for STAT6 in perpetuating inflammation in a mouse model similar to ulcerative colitis. 

Dr. Rosen is currently funded by the National Institutes of Health (NIH) to study the expression of genes related to Th2 inflammation in colon tissue form a large cohort of children with IBD.  In addition, his laboratory is conducting ongoing studies with transgenic animal models to determine the mechanisms by which proteins important in perpetuating Th2 inflammatory responses contribute to inflammation in colitis. 

Dr. Rosen serves on the National Pediatric Affairs Committee for the Crohn's & Colitis Foundation of America (CCFA).  His a past recipient of the Fellow to Faculty Transition Award in IBD and the George Ferry Young Investigator Award from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN).

Education and Training

MD: Harvard Medical School, Boston, MA, 2003.

Residency: Boston Combined Residency Program in Pediatrics (Boston Children's Hospital and Boston Medical Center), Boston, MA, 2003-2006.

Fellowship: Pediatric Gastroenterology, Hepatology, and Nutrition, Vanderbilt University Medical Center and the Monroe Carell, Jr. Children's Hospital at Vanderbilt, Nashville, TN  2006-2009.

Masters of Science in Clinical Investigation (MSCI): Vanderbilt University School of Medicine, Nashville, TN, 2009.

Certification: Pediatrics, 2007; Pediatric Gastroenterology, Hepatology and Nutrition, 2009.


View PubMed Publications


Th2 Cytokines and Signaling in Pediatric Inflammatory Bowel Disease. Principal Investigator. National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases (NIH/NIDDK). Mar 2013-Mar 2018.

Myeloid Cell-Derived IL-33 in Chronic IL-10-Deficient Colitis. Principal Investigator. Cincinnati Children's Research Foundation. Jul 2014-Jun 2016.