A photo of Yrina Rochman.

Yrina Rochman, PhD


  • Research Associate, Division of Allergy and Immunology
  • Instructor, UC Department of Pediatrics

About

Biography

Yrina earned her PhD from the Hebrew University of Jerusalem. She completed her post-doctoral training in molecular immunology at National Institutes of Health in the laboratory of Dr. Warren Leonard, where she published several papers and reviews in high profile peer-reviewed journals. She is a recipient of the Lenfant Biomedical Award from NHLBI, NIH for outstanding research. Her research is focused on elucidating molecular mechanisms of immunological responses.

PhD: Hebrew University of Jerusalem, Israel, 2005.

Post-Doc Fellowship: NHLBI/National Institutes of Health, Bethesda, MD, 2005-2011.

Research Associate: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2012-2013.

Research Instructor: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2013-present.

Interests

Immunology

Publications

TSLP shapes the pathogenic responses of memory CD4+ T cells in eosinophilic esophagitis. Rochman, Y; Kotliar, M; Morgenstern, NB B; Barski, A; Wen, T; Rothenberg, ME. Science Signaling. 2023; 16:eadg6360.

The minichromosome maintenance complex drives esophageal basal zone hyperplasia. Rochman, M; Rochman, Y; Caldwell, JM; Mack, LE; Besse, JA; Manes, NP; Yoon, SH; Shoda, T; Nita-Lazar, A; Rothenberg, ME. JCI insight. 2023; 8:e172143.

Local type 2 immunity in eosinophilic gastritis. Ben-Baruch Morgenstern, N; Shoda, T; Rochman, Y; Caldwell, JM; Collins, MH; Mukkada, V; Putnam, PE; Bolton, SM; Felton, JM; Rochman, M; et al. Journal of Allergy and Clinical Immunology. 2023; 152:136-144.

Environmental allergens trigger type 2 inflammation through ripoptosome activation. Brusilovsky, M; Rochman, M; Rochman, Y; Caldwell, JM; Mack, LE; Felton, JM; Habel, JE; Porollo, A; Pasare, C; Rothenberg, ME. Nature Immunology. 2021; 22:1316-1326.

Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. Wen, T; Aronow, BJ; Rochman, Y; Rochman, M; Kiran, KC; Dexheimer, PJ; Putnam, P; Mukkada, V; Foote, H; Rehn, K; et al. The Journal of Clinical Investigation. 2019; 129:2014-2028.