Saulius Sumanas, PhD

Assistant Professor, UC Department of Pediatrics

Phone 513-803-0435

Fax 513-636-4317

Email saulius.sumanas@cchmc.org

Molecular mechanisms of vasculogenesis and angiogenesis

Visit the Sumanas Lab.

BS: Vilnius University, Biochemistry, Vilnius, Lithuania, 1995.

PhD: University of Minnesota, Department of Biochemistry, Minneapolis / St. Paul, MN, 2000.

Postdoctoral Fellow: University of California, Los Angeles, CA, 2002-2007.

View PubMed Publications

Glenn NO, McKane M, Kohli V, Wen KK, Rubenstein PA, Bartman T, Sumanas S. W-Loop of Alpha-Cardiac Actin is Critical for Heart Function and Endocardial Cushion Morphogenesis in Zebrafish. Mol Cell Biol. 2012 Sep;32(17):3527-40.

Wong KS, Rehn K, Palencia-Desai S, Kohli V, Hunter W, Uhl JD, Rost MS, Sumanas S. Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish. Dev Biol. 2012 Jan 15:361:377-91.

Palencia-Desai S, Kohli V, Kang J, Chi NC, Black BL, Sumanas S. Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function. Development. 2011 Nov;138(21):4721-32.

Proulx K, Wong KS, Balciunas D, Sumanas S.Zebrafish Enhancer Trap Line Recapitulates Embryonic aquaporin 1a Expression Pattern In Vascular Endothelial Cells. Int J Dev Biol. 2011;55(6):613-8.

Kohli V, Rehn K, Sumanas S. Single cell fate mapping in zebrafish. J Vis Exp. 2011 56, e3172.

Proulx K, Lu A, Sumanas S. Cranial vasculature in zebrafish forms by angioblast cluster-derived angiogenesis. Dev Biol. 2010 Dec 1;348(1):34-46.

Wong KS, Proulx K, Rost MS, Sumanas S. Identification of vasculature-specific genes by microarray analysis of Etsrp/Etv2 overexpressing zebrafish embryos. Dev Dyn. 2009 Jul;238(7):1836-50.

Sumanas S, Gomez G, Zhao Y, Park C, Choi K, Lin S. Interplay between Etsrp/ER71, scl and alk8 signaling controls endothelial and myeloid cell formation. Blood. May. 2008 111(9):4500-4510.

Sumanas S, Lin S.  Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLOS Biol. 2006 Jan;4(1):e10.

Sumanas S, Jorniak T, Lin S. Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants. Blood. 2005 Jul;106(2):534-541.