Saulius Sumanas, PhD

Assistant Professor, UC Department of Pediatrics

Phone 513-803-0435

Fax 513-636-4317

Email saulius.sumanas@cchmc.org

Molecular mechanisms of vasculogenesis and angiogenesis

Visit the Sumanas Lab.

BS: Vilnius University, Biochemistry, Vilnius, Lithuania, 1995.

PhD: University of Minnesota, Department of Biochemistry, Minneapolis / St. Paul, MN, 2000.

Postdoctoral Fellow: University of California, Los Angeles, 2002-2007.

Glenn NO, McKane M, Kohli V, Wen KK, Rubenstein PA, Bartman T, Sumanas S. W-Loop of Alpha-Cardiac Actin is Critical for Heart Function and Endocardial Cushion Morphogenesis in Zebrafish. Mol Cell Biol, in press. 2012.

Wong KS, Rehn K, Palencia-Desai S, Kohli V, Hunter W, Uhl JD, Rost MS, Sumanas S.Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish. Dev Biol 361, 377-391. 2012.

Palencia-Desai S, Kohli V, Kang J, Chi NC, Black BL, Sumanas S. Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function. Development 138, 4721-4732. 2011.

Proulx K, Wong KS, Balciunas D, Sumanas S.  Zebrafish Enhancer Trap Line Recapitulates Embryonic aquaporin 1a Expression Pattern In Vascular Endothelial CellsInt J Dev Biol. 2011.

Kohli V, Rehn K, Sumanas S. Single cell fate mapping in zebrafish. J Vis Exp 56, e3172.  2011.

Proulx K, Lu A, Sumanas S. Cranial vasculature in zebrafish forms by angioblast cluster-derived angiogenesis. Dev Biol. Dec 1;348(1):34-46. 2010.

Wong KS, Proulx K, Rost MS, Sumanas S. Identification of vasculature-specific genes by microarray analysis of Etsrp/Etv2 overexpressing zebrafish embryos. Dev Dyn. Jul;238(7):1836-50. 2009.

Sumanas S, Gomez G, Zhao Y, Park C, Choi K, Lin S. Interplay between Etsrp/ER71, scl and alk8 signaling controls endothelial and myeloid cell formation. Blood. May;111(9):4500-4510. 2008.

Sumanas S, Lin S.  Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLOS Biol. Jan;4(1):e10. 2006.

Sumanas S, Jorniak T, Lin S. Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants. Blood. Jul;106(2):534-541. 2005.