In my research, I focus on trying to better understand how seizures start and spread in the brain. To accomplish this goal, I use noninvasive neuroimaging technologies and neurophysiology techniques.
My research is a natural extension of my PhD thesis work with rats and monkeys — as a student in a combined MD/PhD program, I was interested in the brain. But I also enjoyed caring for children, and I wanted to shift my research to them. My thesis focused on better understanding brain networks involved in a particular type of pediatric epilepsy. During this work, I met a pediatric neurologist who ultimately influenced me to pursue clinical and research work in pediatric epilepsy.
Now, I specialize in epilepsy, clinical neurophysiology, electroencephalography (EEG) and magnetoencephalography (MEG). My current research efforts focus on understanding the brain networks responsible for seizures so clinicians can devise better ways of stopping them. Specifically, I study generalized seizures which researchers typically consider having no focal onset.
My research and clinical work are closely tied. I am the clinical director of the Cincinnati Children’s Hospital Medical Center MEG Center. Clinicians use the center’s services for pre-surgical evaluations of pediatric epilepsy patients. I also evaluate and manage patients with epilepsy in the outpatient epilepsy clinic and the Epilepsy Monitoring Unit, with a special interest in children diagnosed with childhood absence epilepsy (CAE).
I am the current President of the American Clinical MEG Society (ACMEGS). I am a member of the American Epilepsy Society, the Organization for Human Brain Mapping and the Child Neurology Society. I also received the Taking Flight Award from Citizens United for Research in Epilepsy (CURE).
MD/PhD: University of Massachusetts Medical School, Worcester, MA, 2006.
Residency: Child Neurology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2011.
Fellowship: Clinical Neurophysiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2011.
Certification: Neurology with Special Qualifications in Child Neurology, 2011; American Board of Clinical Neurophysiology, 2012; Epilepsy, 2013.
Neurology; epilepsy; electroencephalography (EEG); magnetoencephalography (MEG); functional MRI
Imaging; MEG; EEG; epilepsy; epilepsy surgery
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Responsive Neurostimulation of Thalamic and Nonthalamic Targets in Pediatric and Young Adult Patients With Intractable Epilepsy. Neurosurgery. 2026; 98(1):204-210.
Localization and duration dependent effects of pediatric refractory epilepsy on language function. Epilepsy and Behavior. 2026; 174:110813.
93 Electroclinical Syndromes: Childhood Onset. In: Swaiman's Pediatric Neurology. Elsevier; 2026:845-852.e3.
Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function. Nature Genetics. 2025; 57(11):2691-2704.
Intracranial High-Frequency Oscillations and Epileptogenic Zone: Incorporating Neuroanatomic Variation. Journal of Clinical Neurophysiology. 2025.
User-defined virtual sensors: A new solution to the problem of temporal plus epilepsy sources. Epilepsia. 2025; 66(4):1071-1083.
Altered cortical excitability in tuberous sclerosis and the effect of mTOR inhibitors: An intracranial electrical stimulation study. Clinical Neurophysiology. 2025; 172:1-9.
Electroclinical Syndromes: Childhood Onset. In: Swaiman S Pediatric Neurology Principles and Practice. 2025:845-852.e3.
Emotional facial expression and perioral motor functions of the human auditory cortex. Clinical Neurophysiology. 2024; 163:102-111.
Role of optically pumped magnetometers in presurgical epilepsy evaluation: Commentary of the American Clinical Magnetoencephalography Society. Epilepsia. 2023; 64(12):3155-3159.
Jeffrey R. Tenney, MD, PhD, Hansel M. Greiner, MD1/7/2025
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