Cytotoxic lymphocyte function; gene therapy to correct lymphocyte dysfunction
Alexandra Vrazo, PhD, MPH, earned a BSc in Virology and Immunology at the University of Bristol, England. Through the Northwestern University Feinberg School of Medicine, she completed a joint PhD in Microbiology and Immunology and a Masters in Public Health focusing on tuberculosis control. Her interests span lymphocyte function, translational research and global health.
Education and Training
PhD: Northwestern University, Evanston, IL, 2012.
MPH: Northwestern University, Evanston, IL, 2012.
View PubMed Publications.
Amick AC, Chauchard M, Cen O, Longnecker R. Animal Models of Burkitt’s Lymphoma. In: Robertson, E (Ed) Burkitt’s Lymphoma. Springer: New York. 2013.
Vrazo AC, Chauchard M, Raab-Traub N, Longnecker R. Epstein-Barr Virus LMP2A Reduces Hyperactivation Induced by LMP1 to Restore Normal B Cell Phenotype in Transgenic Mice. PLoS Pathog. 2012 8(4).
Makedonas G, Hutnick N, Haney D, Amick AC, Gardner J, Cosma G, Hersperger AR, Dolfi D, Wherry EJ, Ferrari G, Betts MR. Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells. PLoS Pathog. 2010 Mar 5;6(3).
Bieging KT, Swanson-Mungerson M, Amick AC, Longnecker R. Epstein-Barr virus in Burkitt’s lymphoma: A role for latent membrane protein 2A. Cell Cycle. 2010 Mar;9(5):901-8.
Bieging KT, Amick AC, Longnecker R. Epstein-Barr virus LMP2A bypasses p53 inactivation in a Myc model of lymphomagenesis. Proc Natl Acad Sci USA. 2009 Oct 20;106(42):17945-50.