Charles V. Vorhees, PhD

Professor, UC Department of Pediatrics

Phone: 513-636-8622

Fax: 513-636-3912


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Principal areas of investigation are how drugs, genetic mutations, environmental agents, and stressors affect prenatal and neonatal brain development and behavior.  The lab is particularly interested in the long-term effects of such perturbations on cognitive development.

Visit the Vorhees-Williams-Skelton Lab.


Dr. Vorhees came to Cincinnati Children’s in 1976 as a postdoctoral research scholar and was recruited to the faculty in 1978 as assistant professor. He was promoted to associate professor in 1982, tenured in 1984, and promoted to professor in 1988 with primary appointment in pediatrics and joint appointment in environmental health. He is co-director of the Animal Behavior Core and program director of the Teratology Training Program.  He is on the graduate faculty of the Graduate Programs in Neuroscience (NS) and Molecular and Developmental Biology (MDB). He is section editor of the journal Neurotoxicology and Teratology and served as editor-in-chief for nine years. He was director of the MDB Graduate Program for six years and served in other leadership positions for 15 years. Dr. Vorhees has also served in leadership positions in the NS Program and is currently a member of the Admissions Committee. Dr. Vorhees has been extramurally funded for 35 years, receiving grants from NIH, NSF, FDA and other agencies. He holds an NIH T32 training grant funded for years 36-40 through 2017.  He is a founding member of the Neurobehavioral Teratology Society in 1977 and was elected president in 1984-85 and 2012-13.  He is an elected member of Sigma Xi, an Eli Lilly Distinguished Lecturer in 1990, and a Society for Neuroscience Grass Foundation Lecturer in 2002.  Dr. Vorhees has served on multiple FDA, NRC, and EPA advisory panels.  He has been an NIH grant reviewer on varies committees for more than 26 years.  He has also reviewed grants for NSF, VA, EPA; March of Dimes, and other agencies and foundations in the U.S.; and for funding agencies in Israel, Ireland, Great Britain, and New Zealand.  His research focuses on brain development and behavior.  As of 2013 he has published than more 276 journal articles and book chapters.

Visit the Vorhees Lab Site

Visit the Animal Behavioral Core Site

Education and Training

MA: Neurobiology Program, Vanderbilt University, Nashville, TN, 1973.

PhD: Neurobiology Program, Vanderbilt University, Nashville, TN, 1976.


View PubMed Publications


Selective disruption of hippocampal dentate granule cells in autism: impact of PTEN deletion. Co-Investigator, National Institutes of Health. 2009-2014

Acute neurotoxicity of pyrethroids. Principal Investigator. CAPHRA. 2012-2014.

Prenatal SSRI Exposure and ASD. Principal Investigator. Congressionally Directed Medical Research Program, Department of Defense. 2013-2015.

Latrophilin-3 and ADHD: A new potential mechanism. Principal Investigator. National Institutes of Health.  2013-2015.

Training Grant in Teratology. Principal Investigator. National Institutes of Health. 2012-2017.