Biographies

E-mail this page

(All fields required)

Recipient's email address

Please enter a valid email.

Your name

Please enter your name.

Your email address

Please enter a valid email.

Find another Doctor or Researcher

High Res

Stavra A. Xanthakos, MD, MS

Medical Director, Surgical Weight Loss Program for Teens

Co-Director, Steatohepatitis Center

Assistant Professor, UC Department of Pediatrics

Phone: 513-636-4415

Fax: 513-636-7805

Email: stavra.xanthakos@cchmc.org

Show All

Specialties

Research Interests

Prevalence, determinants and outcome of pediatric obesity-related liver disease (Non-alcoholic fatty liver disease and steatohepatitis); bariatric medicine; pediatric obesity and nutrition

Clinical Interests

Non-alcoholic fatty liver disease and steatohepatitis; pediatric obesity; bariatric surgery; nutrition

Biography

Stavra A. Xanthakos, MD, is an assistant professor in the Division of Gastroenterology, Hepatology and Nutrition and the co-director of the Cincinnati Children’s Steatohepatitis Center, the medical director of the Surgical Weight Loss Program for Teens, and an attending physician in the Gastroenterology Division. She also partners with physicians and staff in Cincinnati Children’s Center for Better Health and Nutrition in the evaluation and management of pediatric patients suffering from severe pediatric obesity and related complications.

Dr. Xanthakos received her medical degree from Duke University in 1997 and a Master of Science degree in Molecular Epidemiology from the University of Cincinnati in 2006. Her post-doctoral training, including residency, chief residency and fellowship were completed at Cincinnati Children's and she joined the faculty in 2005. During her fellowship, Dr. Xanthakos investigated the prevalence and outcome of non-alcoholic fatty liver disease (NAFLD) in young adult women as her master’s thesis in molecular epidemiology. Her current clinical and translational research is focused on identify the predictors and outcome of obesity-related liver disease (nonalcoholic fatty liver disease and steatohepatitis), in obese adolescents undergoing bariatric surgery. She is also a co-investigator in the NIH sponsored Teen LABS, a multicenter consortium investigating bariatric surgery in adolescents and in the NIH-sponsored NASH Clinical Research Network. Additional research interests of Dr. Xanthakos include the treatment and prevention of pediatric obesity, outcomes of bariatric surgery in adolescents, malnutrition in pediatric obesity, as well as identifying genetic and environmental risk factors for pediatric nonalcoholic fatty liver disease to enable better evaluation and treatment options. She also leads clinical quality improvement initiatives in the Steatohepatitis Center, which are aligned with divisional and institutional initiatives to achieve measurable improvements in children’s health and disease outcomes.

Dr. Xanthakos has published extensively in the field of pediatric obesity, bariatric medicine and non-alcoholic fatty liver disease. She regularly is invited to speak about pediatric obesity evaluation and management, particularly bariatric medicine, and pediatric nonalcoholic fatty liver disease.

Education and Training

MD: Duke University, Durham, NC, 1997.

MS: Molecular Epidemiology, University of Cincinnati, 2006.

Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1997-2000.

Chief Residency: Cincinnati Children's, Cincinnati, OH, 2000-01.

Clinical Fellowship: Gastroenterology, Hepatology & Nutrition, Cincinnati Children's , Cincinnati, OH, 2001-2004.

Research Fellowship: Molecular Epidemiology in Children's Environmental Health, Masters of Science, 2002-2005.

Certification: Pediatrics, 2008; Pediatric Gastroenterology, 2005.

Publications

View PubMed Publications

Carter-Kent C, Alkhouri N, Yerian LM, Brunt EM, Angulo P, Kohli R, Ling SC, Xanthakos SA, Whitington PF, Charatcharoenwitthaya P, Yap J, Lopez R, McCullough AJ and Feldstein AE. The relationship of steatosis grade, zone and type to key histological features in children with nonalcoholic fatty liver disease. Journal of Pediatric Gastroenterology, Hepatology and Nutrition. 2011;52(2):190-7.

Kohli R, Kirby M, Xanthakos SA, Softic S, Feldstein AE, Saxena V, Tang PH, Miles L, Miles MV, Balistreri WF, Woods SC, Seeley RJ. High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology. 2010 Sep;52(3):934-44.

Kohli R, Boyd T, Lake K, Dietrich K, Nicholas L, Balistreri WF, Ebach D, Shashidhar H, Xanthakos SA. Rapid progression of NASH in childhood. J Pediatr Gastroenterol Nutr. 2010 Apr;50(4):453-6.

Xanthakos SA. Nutritional deficiencies in obesity and after bariatric surgery. Pediatr Clin North Am. 2009 Oct;56(5):1105-21.

Inge TH, Xanthakos S. Sleeve gastrectomy for childhood morbid obesity: why not? Obes Surg. 2010 Jan;20(1):118-20.

Inge TH, Jenkins TM, Zeller M, Dolan L, Daniels SR, Garcia VF, Brandt ML, Bean J, Gamm K, Xanthakos SA. Baseline BMI is a strong predictor of nadir BMI after adolescent gastric bypass. J Pediatr. 2010 Jan;156(1):103-108

Xanthakos SA. Bariatric surgery for extreme adolescent obesity: Indications, outcomes, and physiologic effects on the gut-brain axis. Pathophysiology. 2008 Aug;15(2):135-46.

Roehrig HR, Xanthakos SA, Sweeney J, Zeller MH, Inge TH. Pregnancy after gastric bypass surgery in adolescents. Obes Surg. 2007 Jul;17(7):873-7.

Miller RJ, Xanthakos SA, Hillard PJ, Inge TH. Bariatric surgery and adolescent gynecology. Curr Opin Obstet Gynecol. 2007 Oct;19(5):427-33.

Inge TH, Xanthakos SA, Zeller MH. Bariatric surgery for pediatric extreme obesity: now or later? Int J Obes (Lond). 2007 Jan;31(1):1-14.

Grants

Adolescent Bariatrics: Assessing Health Benefits and Risks. Co-Investigator. National Institutes of Health. July 2006 - April 2011. #U01DK072493.

Coenzyme Q as a Novel Biomarker for the Severity of Steatohepatitis. Co-Principal Investigator. National Institutes of Health. Jun 2010 - May 2011. #P30DK078392.

Biological Determinants of Steatohepatitis after Adolescent Bariatric Surgery. Principal Investigator. National Institutes of Health. July 2008 - June 2013. #1K23DK080888.

Clinical Research Network in Non-Alcoholic Steatohepatitis (NASH CRN). Site Principal investigator. National Institutes of Health. Aug 2009 - Apr 2014. #U01DK061732.