Biographies

Yan Xu, PhD

Director, Bioinformatics Microarray Core

Associate Professor, UC Department of Pediatrics

Phone: 513-636-8921

Fax: 513-636-7868

Email: yan.xu@cchmc.org

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Specialties

Bioinformatics; systems biology application in pulmonary research; lung cell type specific signaling; asthma associated pathology

Biography

Yan Xu, PhD, is an associate professor in the Department of Pediatrics, Divisions of Pulmonary Biology and Biomedical Informatics. Her main research interests are bioinformatics applications and systems biology.  She is currently focusing on the identification of gene signatures, regulatory networks and biological pathways controlling 1) surfactant homeostasis, 2) lung maturation and 3) lung cell type specific signaling. Her research goal is to integrate the data and information from new computational methods and experimental approaches in a synergistic way to gain better understanding of molecular mechanisms underlying lung development and pathogenesis.

Education and Training

BS: Pharmacology, Shanghai Medical University, China, 1986.

MS: Pathology, Shanghai Medical University, China, 1989.

PhD: Molecular and Cellular Pharmacology, University of South Alabama, Mobile, Alabama, 1997.

Publications

View PubMed Publications

Grants

Transcriptional Control of Respiratory Epithelial Progenitor Cells. Co-investigator. National Heart, Lung and  Blood Institute. Sep 2007 - Sep 2011. #5R01HL090156-02.

Role of SFTPC in Pathogenesis of Interstitial Lung Disease. Co-investigator. National Institutes of Health. Dec 2008 - Nov 2013. #1R01HL086492-01A2.

Role of C/EBPa in Cytoprotection and Recovery from Lung Injury. Co-investigator. National Heart, Lung and  Blood Institute. Apr 2009 - Mar 2014. #1R01HL095464-01.

Transcriptional Programming of Asthma Related Pathology in Respiratory Epithelial. Co-investigator. National Heart, Lung and  Blood Institute. Apr 2009 - Mar 2014. #1R01HL095589-01.