Katherine Yutzey, PhD

Professor, UC Department of Pediatrics

Phone: 513-636-8340

Fax: 513-636-5958


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Molecular regulation of heart development; valve development and disease mechanisms; cardiomyocyte proliferation, cardiac connective tissue lineages.

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Katherine E. Yutzey, PhD, is a professor who joined the Division of Molecular Cardiovascular Biology at Cincinnati Children's Hospital Medical Center in 1995.

Dr. Yutzey is the first recipient of the Fifth Third Bank/Charlotte R. Schmidlapp Women Scholars Award and was also a recipient of a Children's Hospital Medical Center Trustee Award. Her work is also supported by grants from National Institutes of Health (NIH) and the American Heart Association.

The focus of Dr. Yutzey's research program is the regulation of normal and abnormal heart development. Congenital heart defects represent one of the most common classes of human birth defects. Increasing evidence exists for a genetic basis of certain instances of congenital heart disease.

Dr. Yutzey’s lab also studies molecular mechanisms of cardiac connective tissue cell lineage development and disease.  This work focuses on heart valve development and disease as well as mechanisms of cardiac fibrosis.

Education and Training

BA: Oberlin College, Oberlin, OH, 1986.

PhD: Purdue University, West Lafayette, IN,1992

Fellowship: Cornell University Medical College, New York, NY,1992-1995.


View PubMed Publications


Twist1 regulation of valve progenitors.wist1 regulation of valve. National Institutes of Health. 2010-2015. R01 HL082716.

Wnt signaling in heart valve development and disease. Principal Investigator. National Institutes of Health. 2012-2016. #R01 HL094319.

Cell signaling mechanisms of calcific aortic valve disease. Principal Investigator. National Institutes of Health.
2012-2016. #R01 HL114682. 

Trainee support

The role of COX2 in the progression of human and mouse aortic valve disease. Elaine Wirrig, Fellow. K Yutzey, Sponsor. NIH NHLBI Post-Doctoral Fellowship. 2012-2014. F32 HL110390.