Basilia Zingarelli, MD, PhD

Director, Basic Science Research

Professor, UC Department of Pediatrics

Phone: 513-636-8704


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Sepsis; trauma; hemorrhagic shock and ischemia and reperfusion injury.
Visit the Zingarelli Lab.


Basilia Zingarelli, MD, PhD, came to Cincinnati Children's Hospital Medical Center in 1995 as a post-doctoral research fellow in Critical Care Medicine. She joined the faculty in 1997.

Dr. Zingarelli graduated from the Medical School of the University of Messina in Italy in 1990. She also obtained a doctorate in experimental medicine in 1997 and attended a residency in medical toxicology at the University of Messina from 1990 to 1992.

Dr. Zingarelli now directs the basic science research in the Division of Critical Care Medicine. She directs an NIH-funded research laboratory focused on the pathogenetic mechanisms of organ injury during sepsis, trauma and hemorrhage and coordinates basic science and clinical translational research projects related to other critical care conditions.

Dr. Zingarelli serves on the Executive Council of the Shock Society, a well-established international association of clinical and research scientists in the field of shock and trauma, and serves as associate editor for the journal Shock. She also serves as permanent and ad hoc member on a number of study sections at the National Institutes of Health.

Education and Training

MD: School of Medicine, University of Messina, Italy, 1990.

PhD: Experimental Medicine, School of Medicine, University of Messina, Italy, 1997.

Residency: Medical Toxicology, School of Medicine, University of Messina, Italy, 1990-1992.

Certification: General Medicine (Italian), 1990.


View PubMed Publications


Role of Eicosanoids In Shock. Co-Investigator. National Institutes of Health. Jul 2008 - Jun 2012. #R01 GM 027673.

Mechanisms of Age-Related Inflammatory Response in Hemorrhagic Shock. Principal Investigator. National Institutes of Health. Sep 2007 - Aug 2012. #R01 AG 027990.

Host response to trauma research training program. Faculty/mentor. National Institutes of Health (T32 GM08478). Jul 2003-Jun 2013.

Interferon-mediated reprogramming of Toll-like receptor signaling. Co-Investigator. National Institutes of Health. Jul 2008 - Jun 2013. #R01 GM085063.

Role of PPARgamma and PPARgamma Agonists in Septic Shock. Principal Investigator. National Institutes of Health. Jul 2008 - Jun 2013. #R01 GM 067202.

MMP-8 as a novel therapeutic target in sepsis. Co-Investigator. National Institutes of Health. Jul 2011 - Jun 2015. #R01 GM096994.