Reproductive Biology
Reproductive System Conditions
- Cancer
- Congenital bleeding disorders
- Germ cell tumors
- Infertility
- Infertility
- Intrauterine growth retardation
- Pre-eclampsia
- Spontaneous abortion
View a complete list of the diseases that our students and faculty are fighting.
Research in these areas include:
- The basis of genetic or drug-induced congenital malformations, attempting to prevent birth defects in some of the 150,000 afflicted babies born each year.
- The processes of gametogenesis, egg maturation, embryo implantation, and gonad development, cellular processes that are prime targets for new contraceptive methods and infertility treatments. Other research includes the etiology of germ cell tumors, which are one of the most common tumors arising in children.
Faculty
- Timothy Crombleholme, MD, Professor
- Role of endothelial precursor cells in response to injury and molecular fetal therapy.
- Sandra Degen, PhD, Professor
- Molecular genetics of growth factors and blood coagulation proteins
- Stuart Handwerger, MD, Professor
- Placental and decidual gene expression
- Susan Waltz, PhD, Associate Professor
- Molecular analysis of growth factors and receptor tyrosine kinases in tumorigenesis, organ function, and cellular trauma
- Michael Williams, PhD, Research Assistant Professor
- Interaction of stress-induced hormones and drugs of abuse on adult learning and memory abilities; physiological responses to later stressors; behavioral and physiological consequences of drug reexposure. [Visit the Michael Williams Lab]
- Christopher Wylie, PhD, Professor
- (1) Control of the cytoskeleton, control of cell migration and control of early cell lineage specification, in vertebrate embryos (2) Control of gonad formation, primordial germ cell migration, oocyte maturation and egg formation [Visit the Wylie-Heasman Lab]
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
