Prasad Devarajan, MD
Louise M. Williams Endowed Chair, Director of Nephrology and Hypertension
Professor of Pediatrics and Developmental Biology
Education and Training
- Premedical Studies: Bombay University, India, 1979
- MD, Bombay University, India, 1985
Research Interests
Dr. Devarajan studies the molecular mechanisms underlying the response of the kidney to various forms of injury, and the determinants of renal regeneration that are shared by the developing kidney.
Clinical Interests
Novel biomarkers and treatments of acute renal failure
Representative Recent Publications
- Mitsnefes M, Kimbal T, Kartal J, Kathman T, Mishra J, Devarajan P. Serum cystatin C and left ventricular diastolic dysfunction in children with chronic kidney disease. Pediatr Nephrol. 2006 Sep;21(9):1293-1298. Epub 2006 May 24.
- Brunner HI, Mueller M, Rutherford C, Passo MH, Witte D, Grom A, Mishra J, Devarajan P. Urinary neutrophil gelatinase-associated lipocalin as a biomarker of nephritis in childhood-onset systemic lupus erythematosus. Arthritis Rheum. 2006 Jul 25;54(8):2577-2584
- Parikh CR, Jani A, Mishra J, Ma Q, Kelly C, Barasch J, Edelstein CL, Devarajan P. Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation. Am J Transplant. 2006 Jul; 6(7):1639-45.
- Parikh CR, Mishra J, Thiessen-Philbrook H, Dursun B, Ma Q, Kelly C, Dent C, Devarajan P, Edelstein CL. Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery. Kidney Int. 2006 Jul; 70(1):199-203.
- Devarajan P (2005). Cellular and molecular derangements in acute tubular necrosis. Curr Opin Pediatr. R. Johnston, Lippincott Williams & Wilkins. 17: 193-9.
- Devarajan P, Tarabishi R, Mishra J, Ma Q, Kourvetaris A, Vougiouka M, Boulikas T. (2004) Low renal toxicity of lipoplatin compared to cisplatin in animals. Anticancer Res 24:2193-200.
- Dixon BP, Devarajan P, Mitsnefes M. (2005) Neonatal renovascular hypertension due to prenatal traumatic retroperitoneal hematoma. Pediatr Nephrol 20:670-2.
- Erkan E, Garcia CD, Patterson LT, Mishra J, Mitsnefes MM, Kaskel FJ, Devarajan P. (2005) Induction of renal tubular cell apoptosis in focal segmental glomerulosclerosis: roles of proteinuria and Fas-dependent pathways. J Am Soc Nephrol 16:398-407.
- Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, Kelly C, Ruff SM, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P. (2005) Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 365:1231-8.
- Mishra J, Mori K, Ma Q, Kelly C, Yang J, Mitsnefes M, Barasch J, Devarajan P. (2004) Amelioration of ischemic acute renal injury by neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol 15:3073-82.
- Mori K, Lee HT, Rapoport D, Drexler IR, Foster K, Yang J, Schmidt-Ott KM, Chen X, Li JY, Weiss S, Mishra J, Cheema FH, Markowitz G, Suganami T, Sawai K, Mukoyama M, Kunis C, D'Agati V, Devarajan P, Barasch J. (2005) Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J Clin Invest 115:610-21.
- Schwab K, Witte DP, Aronow BJ, Devarajan P, Potter SS, Patterson LT. (2004) Microarray analysis of focal segmental glomerulosclerosis. Am J Nephrol 24:438-47.
