Mark M. Mitsnefes, MD
Instructor in Pediatrics
Education and Training
- MD, Gorky Medical Institute, Gorky, Russia
- Pediatrics, Miami Children's Hospital, Miami, Florida
- Pediatric Nephrology, Children's Hospital Medical Center, Cincinnati, Ohio
- MS, University of Cincinnati, Cincinnati, Ohio
Clinical Interests
Care of children with chronic renal disease; hypertension.
Research Interests
Dr. Mitsnefes has a research interest in epidemiology of cardiovascular disease in children with chronic renal disease. Especially, he is interested in the effect of hypertension on end-organ damage, including cardiac and vascular morbidity in pediatric patients with chronic renal insufficiency, dialysis and renal transplantation.
Representative Recent Publications
- Dixon BP, Devarajan P, Mitsnefes M. (2005) Neonatal renovascular hypertension due to prenatal traumatic retroperitoneal hematoma. Pediatr Nephrol 20:670-2.
- Erkan E, Garcia CD, Patterson LT, Mishra J, Mitsnefes MM, Kaskel FJ, Devarajan P. (2005) Induction of renal tubular cell apoptosis in focal segmental glomerulosclerosis: roles of proteinuria and Fas-dependent pathways. J Am Soc Nephrol 16:398-407.
- Hanevold CD, Ho PL, Talley L, Mitsnefes MM. (2005) Obesity and renal transplant outcome: a report of the North American Pediatric Renal Transplant Cooperative Study. Pediatrics 115:352-6.
- Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, Kelly C, Ruff SM, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P. (2005) Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 365:1231-8.
- Mishra J, Mori K, Ma Q, Kelly C, Yang J, Mitsnefes M, Barasch J, Devarajan P. (2004) Amelioration of ischemic acute renal injury by neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol 15:3073-82.
- Mitsnefes M, Kimball T, Witt S, Glascock B, Khoury P, Daniels S. (2004) Abnormal carotid artery structure and function in children and adolescents with successful renal transplantation. Circulation 110:97-101.
- Mitsnefes M, Stablein D. (2005) Hypertension in pediatric patients on long-term dialysis: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). Am J Kidney Dis 45:309-15.
- Mitsnefes MM. (2004) Hypertension and end-organ damage in pediatric renal transplantation. Pediatr Transplant 8:394-9.
- Mitsnefes MM. (2005) Cardiovascular morbidity and mortality in children with chronic kidney disease in North America: lessons from the USRDS and NAPRTCS databases. Perit Dial Int 25 Suppl 3:S120-2.
- Mitsnefes MM, Knilans T, Mays W, Khoury PR, Daniels SR. (2005) Blood pressure and total peripheral resistance in children with chronic kidney disease. Pediatr Nephrol 20:803-6.
- Mitsnefes MM, McEnery PT (2005). Hypertension. Pediatrics. L. M. Osborn, T. G. DeWitt, L. R. First and J. A. Zenel. Philadelphia, Elsevier Mosby: 1151-1156.
- Patel HP, Mitsnefes M. (2005) Advances in the pathogenesis and management of hypertensive crisis. Curr Opin Pediatr 17:210-4.
