Faculty

Clark D. West, MD

Emeritus Physician; Emeritus Professor of Pediatrics

Education & Training

  • AB: College of Wooster, OH
  • MD: University of Michigan, Ann Arbor, MI 
  • Pediatrics: University of Michigan, Ann Arbor, MI 
  • Fellowship: Cincinnati Children's Research Foundation

Research Interests

Dr. West is well known for his interest in the abnormalities in the complement system in glomerulonephritis. His special interest concerns circulating complement activators (nephritic factors) found in patients with membranoproliferative glomerulonephritis.

Representative Recent Publications

  • Pan C, Strife CF, McAdams AJ and West CD. Activated C3(C3b) in the nephritic glomerulus. Pediatr Nephrol 7:379-386, 1993.
  • West CD and McAdams AJ, and Welch TR. Glomerulonephritis in Henoch-Schoenlein Purpura without mesangial IgA deposition. Pediatr Nephrol 8:667-683, 1994.
  • West CD. Occasional hypothesis: Nephritic factors predispose to chronic glomerulonephritis. Am J Kid Dis 24: 956-963, 1994.
  • West CD and McAdams AJ. Paramesangial glomerular deposits in membranoproliferative glomerulonephritis type II correlate with hypocomplementemia. Am J Kid Dis 25:853-861, 1995.
  • West CD and McAdams AJ. Glomerular paramesangial deposits: Association with hypocomplementemia in membranoproliferative glomerulonephritis Types I and III. Am J Kid Dis 31:427-434, 1998.
  • West CD and McAdams AJ. Serum and glomerular IgG in poststreptococcal glomerulonephritis are correlated. Pediatr Nephrol 12:392-396, 1998.
  • West CD and McAdams AJ. Membranoproliferative glomerulonephritis type III: Association of glomerular deposits with circulating nephritic factor-stabilized convertase. Am J Kid Dis 32:56-63, 1998.
  • West CD. Complement and glomerular disease. in The Human Complement System in Health and Disease. Frank, M.M. and Volanakis, J.E., Eds. Marcel Dekker.Chap 26, pp 571-596, 1998.
  • West CD and McAdams AJ. Glomerular deposits and hypoalbuminemia in acute post-streptococcal glomerulonephritis. Ped Nephrol 12:471-474, 1998.
  • West CD. Idiopathic membranoproliferative glomerulonephritis in Therapy in Nephrology and Hypertension. H.R. Brady and C.S. Wilcox, Eds., W.B. Saunders Co., Philadelphia, 1999.
  • West CD and McAdams AJ: The alternative pathway C3 convertase and glomerular deposits (Invited Review) Pediatr. Nephrol. 13:448-453, 1999.
  • West CD, McAdams AJ, and Witte DP. Acute non-proliferative glomerulitis: a cause of renal failure unique to children. Pediatr Nephrol 14:786-793, 2000.
  • Strife CF and West CD: Membranoproliferative glomerulonephritis. In Massry S.G. and Glassock R.J. eds. Textbook of Nephrology. Fourth Edition. Baltimore: Lippincott Williams & Wilkins, Chap 39:713-717, 2001.
  • West CD, Witte DP and McAdams AJ: Composition of nephritic factor-generated glomerular deposits in membranoproliferative glomerulonephritis Type 2. Am J Kid Dis 37:1120-1130, 2001.