Kamyar Zahedi, PhD
Research Assistant Professor
Education and Training
- BS, Utah State University
- MS, Utah State University
- PhD, Ohio State University
- Research Fellowship (immunology), Children's Hospital, Harvard Medical School, Boston.
Research Interests
Dr. Zahedi studies the biology of inflammation, specifically the role of gene regulation in promoting the inflammatory response. Recently, his laboratory has expanded its interest to include structure and function of extracellular matrix and its role in tubulogenesis and nephrogenic repair.
Representative Recent Publications
- Barone S, Okaya T, Rudich S, Petrovic S, Tehrani K, Wang Z, Zahedi K, Casero RA, Lentsch AB, Soleimani M. (2005) Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ischemia/reperfusion injury. Am J Physiol Cell Physiol.
- Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, Kelly C, Ruff SM, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P. (2005) Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 365:1231-8.
- Wang Z, Zahedi K, Barone S, Tehrani K, Rabb H, Matlin K, Casero RA, Soleimani M. (2004) Overexpression of SSAT in kidney cells recapitulates various phenotypic aspects of kidney ischemia-reperfusion injury. J Am Soc Nephrol 15:1844-52.
- Zahedi K. Characterization of the binding of serum amyloid P to type IV collagen. J Biol Chem 271:14897-14902, 1996.
- Zahedi K. Characterization of the binding of serum amyloid P to laminin. J Biol Chem 272:2143-2148, 1997.
- Zahedi K, Prada AE, Prada JA, Davis III AE. Characterization of the IFN-( responsive element in the 5N flanking region of the C1inh gene. J Immunol 159:6091-6096, 1977.
- Zahedi K, Bissler JJ, Prada AE, Prada JA, Davis III AE. The promoter of the C1 inhibitor gene contains a polypurineApolypyrimidine segment that enhances transcriptional activity. J Immunol 162:7249-7255, 1999.
- Ochiretor JD, Harrison KA, Zahedi K, Mortensen RF. Role of STAT3 and C/EBP in cytokine dependent expression of the mouse serum amyloid P component (SAP) and C-reactive protein (CRP) genes. Cytokine, 12:888-899, 2000.
