Cardiovascular Biology
Cardiovascular Diseases
- Congenital heart malformation
- Heart failure
- Cardiac Hypertrophy
- Muscular Dystrophy
- Hypertrophic Cardiomyopathy
- Dilated Cardiomyopathy
- Congenital heart defects
- Trisomy 21
- Fetal Alcohol Syndrome
- Heart valve disease
- Ehlers-Danlos Syndrome
- Holt-Oram Syndrome
- Vascular diseases
- Pulmonary hypertension
View a complete list of the diseases that our students and faculty are fighting.
Researchers in this group use state-of-the-art technologies to study normal and abnormal cardiac and vascular function and development in animal model systems and human subjects. A wide variety of experimental approaches are used to identify molecular signals and cellular processes involved in cardiovascular development and disease.
Through a greater understanding of molecular mechanisms, researchers hope to understand and find ways to treat congenital malformations and cardiovascular disease.
Faculty
- Thomas Bartman, MD, PhD, Assistant Professor
- Morphogenesis of the heart. [Visit the Bartman Lab]
- D. Woodrow Benson, MD, PhD Professor
- Identification and analysis of genes that cause congenital heart malformations
- Jay Degen, PhD, Professor
- The role of hemostatic factors and coupled signaling systems in development, inflammatory response, vessel wall disease and tumor biology [Visit the Degen Lab]
- Sandra Degen, PhD, Professor
- Molecular genetics of growth factors and blood coagulation proteins
- Richard Lang, PhD, Professor
- Eye development with an emphasis on lens induction and vascular patterning [Visit the Lang Lab]
- Tim Le Cras, PhD, Associate Professor
- Growth factors in newborn lung development and chronic lung disease in premature infants [Visit the Le Cras Lab]
- Jeffery D. Molkentin, PhD, Professor
- Transcriptional control of cardiac development and the molecular signaling pathways involved in cardiac hypertrophy [Visit the Molkentin Lab]
- Jeffrey Robbins, PhD, Professor
- Molecular basis of heart performance and structure-function characteristics of cardiac contractile proteins related to hypertrophic myopathies [Visit the Robbins Lab]
- Arnold W. Strauss, MD
- Molecular basis of disorders of mitochondrial fatty acid oxidation and the genetic causes of congenital heart disease and cardiomyopathies
- Saulius Sumanas, PhD
- Molecular mechanisms of the embryonic vasculature formation [Visit the Sumanas Lab]
- Stephanie Ware, MD, PhD, Assistant Professor
- Genetics of cardiovascular development [Visit the Ware Lab]
- David Wieczorek, PhD, Professor
- Professor, Analysis of protein expression in normal and diseased cardiac and skeletal muscle
- Katherine Yutzey, PhD, Professor
- Morphogenesis of the heart and transcriptional regulatory networks involved in cardiac determination and differentiation; congenital heart disease [Visit the Yutzey Lab]
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
