Immunology
Immunological Diseases
- Allergic disorders
- Allergy
- Asthma
- Autoimmune disease
- Cystic Fibrosis
- Ebola Virus Hemorrhagic Fever
- Eczema
- Food allergy
- Hepatitis C
- Hypereosinophilic syndromes
- Immunity to viral infection
- Inflammation
- Interstitial Lung Disease
- Leukemia
- Measles
- Multiple Sclerosis
- Pneumia
- Pulmonary Fibrosis
- Sepsis
- Spondyloarthritis
- Uveitis
View a complete list of the diseases that our students and faculty are fighting.
The broad research goals of this research is to understand the cellular, molecular and genetic mechanisms that drive immunologically-mediated disorders.
Dysregulated immune responses are of central importance to the pathogenesis and expression of a wide spectrum of disease (HIV, asthma, coronary artery disease, arthritis, cystic fibrosis, cancers) that cause an immense burden of morbidity and mortality in the US and the world at large.
Faculty
- Robert Colbert, MD, PhD, Associate Professor
- Antigen processing and presentation in autoimmunity; immunoproteasome assembly and function
- Jay Degen, PhD, Professor
- The role of hemostatic factors and coupled signaling systems in development, inflammatory response, vessel wall disease and tumor biology [Visit the Degen Lab]
- Gurjit Hershey, MD, PhD, Assistant Professor
- Genetics and the pathogenesis of atopic disorders.
- David Hildeman, PhD, Assistant Professor
- Molecular biology of antigen-specific T cells, including mechanisms involved in cell signaling, apoptosis, and sex-based differences in autoimmunity and the T cell response to viral infections
- Christopher Karp, MD, Professor
- Characterization of the molecular mechanisms underlying regulation and dysregulation of inflammatory responses in human infections, allergic and autoimmune diseases
- Jonathan Katz, PhD, Associate Professor
- Studies on the immunologic aspects of type 1 diabetes mellitus (autoimmune diabetes) using the nonobese diabetic mouse
- Daniel Nebert, MD, Professor
- Regulation of genes, encoding receptors and drug-metabolizing enzymes important in drug - and environmental - induced toxicity and teratogenesis
- Marc Rothenberg, MD, PhD, Professor
- Eosinophil biology, chemokine receptor signaling pathways
- Timothy E. Weaver, PhD, Professor
- Cytoprotective pathways involved in adaptation to genetic and environmental stresses [Visit the Weaver Lab]
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
