Development of Other Organ Systems
Diseases of Other Organ Systems
- Birth defects
- Congenital cytomegalovirus infection
- Congenital deafness
- Congenital malformations of the ear
- Deafness
- Hearing loss
- Heterotaxy
- Hollow visceral
- Neuromuscular disorders
- Obesity
View a complete list of the diseases that our students and faculty are fighting.
Musculoskeletal | Kidney | Urogenital | Ear | Skin
The research in these areas focuses on understanding the normal development of organs and how abnormal development results in childhood disease.
There are many organ systems affected by pediatric disease. The Cincinnati Children's Hospital Research Foundation has initiated a 7 year expansion project that includes a new state-of-the-art research building and a commitment to hire 19 new faculty members to expand our research into the development and disease of other organ systems.
Faculty
- Daniel Choo, MD, Assistant Professor
- Early inductive signaling events in differentiation and patterning of the mouse inner ear
- George Daston, PhD, Volunteer Professor
- Mechanisms of chemically-induced abnormal development
- Min-Xin Guan, PhD, Associate Professor
- Mitochondrial biogenesis, cellular and molecular biology of mitochondrial disorders, especially in hearing loss, blindness and neuromuscular disorders
- David Hildeman, PhD, Assistant Professor
- Molecular biology of antigen-specific T cells, including mechanisms involved in cell signaling, apoptosis, and sex-based differences in autoimmunity and the T cell response to viral infections
- Chia-Yi (Alex) Kuan, MD, PhD, Assistant Professor
- Understanding the regulation of neuronal cell death and neurogenesis during development and in ischemic brain injury
- James Lessard, PhD, Professor
- Cell and molecular biology of muscle development and function
- Jun Ma, PhD, Associate Professor
- Molecular mechanisms of transcriptional regulaton and development using yeast and Drosophila as model systems
- Sarah Pixley, PhD, Associate Professor
- Neurogenesis and neurotrophic interactions in olfactory neuron cultures and in vivo; neuronal stem cells
- Steven Potter, PhD, Professor
- Studies of homeobox genes that control mamalian development using gene targeting and transgenic mice
- Charles Vorhees, PhD, Professor
- (1) Determine the mechanism of action of substituted amphetamines on brain development and (2) use of gene targeting to determine how deletion of specific brain proteins affect learning and memory [Visit the Vorhees Lab]
- Susan Waltz, PhD, Assistant Professor
- Molecular analysis of growth factors and receptor tyrosine kinases in tumorigenesis, organ function, and cellular trauma
- Laura Woolett, PhD, Professor
- Role of sterols in fetal and placental metabolism
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
