Stem Cell Biology
Stem Cell Conditions and Diseases
- Alzheimer's
- Cancer
- Dev. brain anomaly
- Diabetes
- Nasal cancers
- Neurodegenrative diseases
- Odor dysfunctions
- Olfactory losses
- Parkinson's
- Schizophrenia
- Spinal cord injury
- Stroke
- Traumatic brain injury
View a complete list of the diseases that our students and faculty are fighting.
Research in this area focuses on identifying and manipulating stem cells to replace tissues damaged by disease and injury. It is estimated that many diseases could ultimately be treated with stem cell-based therapies.
Scientists here investigate new ways to use adult and embryonic stem cells to promote regeneration and to generate tissues for transplantation to cure childhood disease. The Cincinnati Children's Research Foundation has initiated a seven-year expansion project that includes a new state-of-the-art research building and a commitment to hire new faculty members that study stem cell biology.
Faculty
- Steve Danzer
- Elucidating the role of neurogenesis in the development of epilepsy. [Visit the Danzer Lab]
- Hartmut Geiger, PhD, Assistant Professor
- Hematopoietic stem cell biology: Combining genetics and molecular biology to investigate DNA repair in hematopoietic stem cells and regulation of stem cell mobilization
- James C. Mulloy, PhD, Assistant Professor
- Molecular mechanisms involved in leukemia induction and maintenance; mouse modeling of leukemia using primary human blood stem cells [Visit the Mulloy Lab]
- Masato Nakafuku, MD, PhD, Professor
- Molecular control of neural stem cells in development and regeneration of mammalian central nervous system [Visit the Nakafuku Lab]
- Sarah Pixley, PhD, Associate Professor
- Neurogenesis and neurotrophic interactions in olfactory neuron cultures and in vivo; neuronal stem cells
- Jim Wells, PhD, Assistant Professor
- Endoderm organogenesis and promoting the differentiation of embryonic stem cells into therapeutic endoderm derivatives. [Visit the Wells Lab]
- David Williams, MD, Professor
- Role of Rho GTPase signaling in blood cell development and function. Retrovirus-mediated gene transfer into hematopoietic stem cells, including use in human genetic diseases and cancer. [Visit the David Williams Lab]
- Yi Zheng, PhD, Professor
- Molecular mechanisms of Rho GTPase signal transduction. Development of novel therapeutic reagents to inhibit Rho pathways related to human pathological conditions
For more information about the Molecular and Developmental Biology Program at Cincinnati Children's and the University of Cincinnati, email mdbprog@cchmc.org or call 513-636-4545. You can also apply online at our application page.
