Clinical Research

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    Faculty

    A photo of Evaline Alessandrini.

    Evaline A. Alessandrini, MD, MSCE
    Director, Quality Scholars Program

    513-803-2046

    evaline.alessandrini@cchmc.org

    Evaline A. Alessandrini, MD, MSCE

    Director, Quality Scholars Program

    Professor, UC Department of Pediatrics

    Phone: 513-803-2046

    Fax: 513-636-0171

    Email: evaline.alessandrini@cchmc.org

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    Biography

    Evaline Alessandrini, MD, MSCE, is an attending physician in the Division of Emergency Medicine at Cincinnati Children’s Hospital Medical Center and a professor of pediatrics at the University of Cincinnati College of Medicine. She is director of the Quality Scholars Program in Health Care Transformation in the James M. Anderson Center for Health Systems Excellence where she leads training for health care faculty to innovate to improve care and rigorously apply quality improvement methods.

    Dr. Alessandrini’s research defines outcomes of quality emergency care and develops interventions to improve delivery of emergency care to children. She served as the American Academy of Pediatrics representative to the National Quality Forum’s Steering Committee on Hospital-based Emergency Care and currently serves as the NACHRI representative to the National Quality Forum’s Steering Committee on Ambulatory Care.

    Education and Training

    MD: Jefferson Medical College, 1988.

    BS: Marquette University (Biology, Summa Cum Laude), 1984.

    MSCE: Master of Science in Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 1999.

    Residency: Children’s National Medical Center, Washington, D.C., 1988 -1991.

    Chief Residency: Children’s National Medical Center, Washington, D.C., 1991- 1992.

    Fellow: Pediatric Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 1992-1995.

    Publications

    View PubMed Publications

    Grants

    EMSC Network Development Demonstration Project. Co-investigator. Sep 2008 - Sep 2011.

    A photo of Raouf Amin.

    Raouf S. Amin, MD
    Director, Division of Pulmonary Medicine

    513-636-6771

    raouf.amin@cchmc.org

    Raouf S. Amin, MD

    Director, Division of Pulmonary Medicine

    Director, Rare Lung Diseases Program

    Professor, UC Department of Pediatrics

    Phone: 513-636-6771

    Fax: 513-636-4615

    Email: raouf.amin@cchmc.org

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    Specialties

    Chronic respiratory failure; sleep disorders in children

    Biography

    Raouf S. Amin, MD, is a professor of pediatrics at Cincinnati Children's Hospital Medical Center and the director of the Division of Pulmonary Medicine. He graduated from the University of Ain Shams in Cairo Egypt in 1977. Dr. Amin received clinical training in the United Kingdom and the United States. He completed a pulmonary fellowship at Cincinnati Children's Hospital Medical Center in 1993. His research focus is on cardiovascular morbidity of sleep disordered breathing in children. He has several funded protocols from the National Institute of Health.

    Education and Training

    MD: Aim Shams University, Cairo Egypt, 1978.

    Residency: Pediatrics; Michigan State University, Flint, MI.

    Certification: Pediatrics 1990; Pediatric Pulmonary Medicine 1994; Sleep Medicine 1995.

    Publications

    View PubMed Publications

    A photo of Bruce Aronow.

    Bruce J. Aronow, PhD
    Co-director, Computational Medicine Center

    513-636-0263

    bruce.aronow@cchmc.org

    Bruce J Aronow, PhD

    Co-director, Computational Medicine Center

    Professor, UC Department of Pediatrics

    Phone: 513-636-0263

    Fax: 513-636-2056

    Email: bruce.aronow@cchmc.org

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    Specialties

    Biography

    Dr. Aronow's research is devoted to unraveling both the role and mechanism by which the functional capabilities of the human genome shape human health and our ability to adapt to stressful challenges. His lab is using a variety of available structural and functional genomic and biological systems descriptive data to form models of how biological systems assemble, adapt and become impaired in disease. The lab's overall hypothesis is that by interconnecting as much experimental and observational information as possible, we can gain new insights into the mechanisms by which different biological systems can achieve health or healthy adaptation, or undergo disease processes. More specific, with the co-leadership of Anil Jegga, DVM, the lab is identifying genetic features that control gene expression including cis-elements, trans factors and microRNAs, which normally work together in extended cell, tissue, organ and systems networks to enable development and homeostasis. Alterations of these features can alter phenotypes and increase or decrease disease. Some of the lab's work includes the identification of conserved, diverged and evolved cis-element clusters that are acted on by transcription and chromatin proteins. The lab has developed a Web-based tool called GenomeTraFaC that at present allows discovery of shared cis-elements in conserved non-coding sequences of mice and humans.

    Education and Training

    BS: Chemistry, Stanford University, Stanford, CA, 1976.

    PhD: Biochemistry, University of Kentucky, Lexington, KY, 1986.

    Research Fellowship: Division of Basic Science Research, Cincinnati Children's Research Foundation, Cincinnati, OH, 1986-1989.

    Publications

    View PubMed Publications

    Grants

    CTSA - Enabling Tehnologies: Center for Translational & Molecular Disease. National Institutes of Health. Apr 2009 - Mar 2014.
    A photo of David Bernstein.

    David I. Bernstein, MD, MA
    Director, Gamble Program and VTEU

    513-636-7625

    david.bernstein@cchmc.org

    David I. Bernstein, MD, MA

    Director, Gamble Program and VTEU

    Professor, UC Department of Pediatrics

    Phone: 513-636-7625

    Fax: 513-636-7682

    Email: david.bernstein@cchmc.org

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    Specialties

    Clinical Interests

    Rotavirus; herpes simplex virus; cytomegalovirus; preclinical and clinical evaluations of vaccine; immune response to herpes virus

    Research Interests

    Evaluation of vaccines and antivirals for herpes and rotovirus; development of improved adjuvants and delivery systems for vaccines; treatment and prevention of influenza, norovirus and parvovirus infections

    Biography

    Dr. Bernstein received his MA degree in microbiology and his MD degree from SUNY at Buffalo. His pediatric training was undertaken at USC and the New England Medical Center. This was followed by an ID fellowship at UCLA.

    During his fellowship he became interested in herpes viruses and vaccines. Upon arrival at Cincinnati Children’s Hospital Medical Center he began his work investigating the immunobiology of genital herpes infections. At this time he also became interested in rotavirus and along with his colleague Dr. Richard Ward he investigated the immune responses that provide protection.

    This work led to the development of a live attenuated human rotavirus vaccine initially named 89-12. The 89-12 vaccine was further modified and became the GlaxoSmithKline rotavirus vaccine, Rotarix, currently available in over 100 countries including the USA and EU. Dr. Bernstein is currently evaluating vaccines for CMV, HSV, influenza, avian influenza, RSV, norovirus and parvovirus. Dr. Bernstein has published over 200 manuscripts and book chapters on infectious diseases, vaccines and antivirals. Dr. Bernstein is currently the Albert Sabin Professor of pediatrics and director of the Division of Infectious Diseases at Cincinnati Children’s and directs one of eight NIH funded Vaccine Evaluation Units.

    Education and Training

    MA: Microbiology, State University of New York at Buffalo, Buffalo, NY, 1973.

    MD: State University of New York at Buffalo School of Medicine, Buffalo, NY, 1977.

    Residency: Pediatrics, University of Southern California Medical Center, Los Angeles, CA; Tufts University School of Medicine, Boston, MA.

    Fellowship: Pediatric Infectious Disease, University of California, Los Angeles, CA.

    Certification: American Board of Medical Examiners, 1978; American Board of Pediatrics, 1981; Pediatrics, 1982.

    Publications

    View PubMed Publications

    Grants

    Vaccine and Treatment Evaluation Units (VTEUs): Evaluation of Control Measures Against Diseases Other Than AIDS. Principal Investigator. 2007 - 2014. #NO1-AI-80006.


    A photo of Frank Biro.

    Frank M. Biro, MD
    Director of Research, Adolescent and Transition Medicine

    513-636-8602

    frank.biro@cchmc.org

    Frank M. Biro, MD

    Director of Research, Adolescent and Transition Medicine

    Professor, UC Department of Pediatrics

    Phone: 513-636-8602

    Fax: 513-636-1129

    Email: frank.biro@cchmc.org

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    Specialties

    Complex medical problems of adolescence; growth; puberty

    Visit the Biro Lab.

    Education and Training

    MD: Harvard Medical School, Boston, MA, 1979.

    Certification: Internal Medicine, September 1983; Pediatrics, November 1986; Adolescent Medicine, February 1995.

    Publications

    View PubMed Publications

    Grants


    A photo of Maria Britto.

    Maria T. Britto, MD, MPH
    Interim Division Director, Adolescent and Transition Medicine

    513-636-8587

    maria.britto@cchmc.org

    Maria T. Britto, MD, MPH

    Interim Division Director, Adolescent and Transition Medicine

    Director, Center for Innovation in Chronic Disease Care

    Assistant Vice President, Chronic Care Systems

    Professor, UC Department of Pediatrics

    Phone: 513-636-8587

    Fax: 513-636-0727

    Email: maria.britto@cchmc.org

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    Specialties

    Clinical Interests

    Chronic illness in adolescents; chronic disease care of adolescents; health care quality

    Research Interests

    Chronic illness in adolescents; health care quality; quality of life; health care preferences of adolescents with chronic illness

    Visit the Britto Lab.

    Biography

    Maria Britto, MD, MPH, is a pediatrician, professor of pediatrics, founding director of the Center for Innovation in Chronic Disease Care, and research faculty mentoring lead for the Anderson Center. She holds an MPH in epidemiology and a graduate certificate in medical informatics. She served as the assistant vice president of Chronic Care Systems from 2007 to 2012.

    Her research focuses on health care needs and preferences of adolescents with chronic conditions and on interventions to improve health outcomes. She is the director of the Center for Innovation in Chronic Disease Care, which seeks to accelerate improvement in outcomes for children and adolescents with chronic conditions by developing and evaluating new methods of care delivery and by applying innovative approaches to quality improvement in chronic diseases. She has served as a mentor for numerous NIH career development awards, as well as numerous other students, residents and junior faculty.

    Education and Training

    MD: University of Virginia, Charlottesville, VA, 1987.

    MPH: Epidemiology, University of North Carolina, Chapel Hill, NC, 1995.

    Residency: Medicine/Pediatrics, University of North Carolina Hospitals, Chapel Hill, NC, 1987-1991.

    Chief Resident: Pediatrics, Department of Pediatrics, University of North Carolina Hospitals, Chapel Hill, NC, 1991-1992.

    Robert Wood Johnson Clinical Scholars Program: University of North Carolina, Chapel Hill, NC, 1993-1995.

    Graduate Certificate: Biomedical Informatics, Oregon Health and Science University, Portland, OR, 2008.

    Board Certifications: American Board of Internal Medicine, 1991; Recertified 2001; American Board of Pediatrics, 1992; Recertified 1999, 2007; American Board of Pediatrics, Certification in Adolescent Medicine, 1997; Recertified 2007 and 2011.

    Licensure: Ohio, July 1995.

    Publications

    View PubMed Publications

    Grants

    Open Source Science: Transforming Chronic Care. Co-Investigator. Oct 2009 – Sep 2014.

    Center of Excellence on Quality of Care Measures for Children with Complex Needs. Site Primary Investigator. Mar 2011 – Feb 2015.

    Improving Sickle Cell Transitions of Care through Health Information Technology, Phase 1. Site Primary Investigator. Aug 2012 – May 2014.


    A photo of John Bucuvalas.

    John C. Bucuvalas, MD
    Associate Medical Director, Pediatric Liver Care Center

    513-636-4415

    john.bucuvalas@cchmc.org

    John C. Bucuvalas, MD

    Associate Medical Director, Pediatric Liver Care Center

    Professor, UC Department of Pediatrics

    Phone: 513-636-4415

    Fax: 513-636-7805

    Email: john.bucuvalas@cchmc.org

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    Specialties

    Liver disease; transplantation; outcomes research; improving the quality of health care delivery.

    Visit the Bucuvalas Lab.

    Biography

    John Bucuvalas, MD, came to Cincinnati Children's Hospital Medical Center in 1982 as a fellow in gastroenterology. He joined the faculty in 1986. He graduated from Harvard College in 1974 and Harvard Medical School in 1978. He completed a pediatric residency at Massachusetts General Hospital and served there as chief resident from 1981 to 1982.

    Over the last 10 years, the focus his patient care and research efforts have been outcomes research and improving the care delivery system for children with chronic liver disease who then may undergo liver transplantation. He has focused on integration of research into patient care and improving the care delivery system. Along the way, he has gained significant content knowledge through traditional research but additionally have learned how to improve processes, understand the system that is academic medicine, interpret variation and recognize the role of leadership both for research and clinical efforts. Dr. Bucuvalas has made significant contributions in the clinical and research arenas towards improving care, enhancing the delivery care and optimizing the outcome of children with chronic liver disease and pediatric liver transplant recipients.

    Dr. Bucuvalas has been recognized as a leader in the field of pediatric hepatology and liver transplantation at a local, regional and national level.

    Education and Training

    AB: Harvard College, Cambridge, MA, 1974.

    MD: Harvard Medical School, Boston, MA, 1978.

    Residency: Pediatrics, Massachusetts General Hospital, Boston, MA, 1978 to 1981.

    Chief Residency: Pediatrics, Massachusetts General Hospital, Boston, MA, 1981 to 1982.

    Fellowship: Gastroenterology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1982 to 85.

    Research Scholar: Gastroenterology, Children's Hospital Research Foundation, Cincinnati, OH, 1985 to 86.

    Certification: Pediatrics, 1983; Pediatric Gastroenterology, 1990; recertified, 1997, 2004.

    Publications

    View PubMed Publications
    A photo of Lee Denson.

    Lee A. Denson, MD
    Medical Director, Inflammatory Bowel Disease Center

    513-636-7575

    lee.denson@cchmc.org

    Lee A. Denson, MD

    Medical Director, Inflammatory Bowel Disease Center

    Professor, UC Department of Pediatrics

    Phone: 513-636-7575

    Email: lee.denson@cchmc.org

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    Specialties

    Inflammatory bowel disease; growth failure; celiac disease

    Visit the Denson Lab.

    Biography

    The primary focus of Dr. Lee A. Denson's laboratory is to determine the molecular basis for alterations in growth hormone signaling in inflammatory bowel diseases (IBD).

    Normal growth and development are dependent upon the ability of growth hormone to regulate IGF-1 expression. Evidence from studies in children with IBD and mouse models of colitis indicates that inflammatory cytokines which are up regulated in this setting may cause an acquired GH resistance. Consequences may include growth failure, altered body composition and impaired mucosal healing.

    We are using complementary experimental and patient-based approaches to investigate regulation of growth hormone signaling in mouse models of colitis and in children with Crohn's disease. These include down regulation of the growth hormone receptor and up regulation of a family of post-receptor inhibitory proteins, the Suppressors of Cytokine Signaling (SOCS). These studies should lead to the development of more effective therapies for children with IBD and other chronic inflammatory conditions.

    Education and Training

    MD: Medical College of Virginia, Richmond, VA, 1993

    Residency: Yale-New Haven Hospital, New Haven, CT, 1993-96.

    Certification: Pediatrics, 1996 & 2002.

    Fellowship: Yale University School of Medicine, New Haven, CT, 1996-99.

    Publications

    View PubMed Publications

    A photo of Prasad Devarajan.

    Prasad Devarajan, MD
    Director, Division of Nephrology and Hypertension

    513-636-4531

    prasad.devarajan@cchmc.org

    Prasad Devarajan, MD

    Director, Division of Nephrology and Hypertension

    Medical Director, Stone Center

    Director, Nephrology and Hypertension Clinical Laboratory

    Louise M. Williams Endowed Chair

    Professor, UC Department of Pediatrics

    Phone: 513-636-4531

    Fax: 513-636-7407

    Email: prasad.devarajan@cchmc.org

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    Specialties

    Clinical specialties: Acute kidney injury, nephrotic syndrome, kidney stones

    Visit the Devarajan Lab.

    Education and Training

    Premedical Studies: Bombay University, India, 1979. 

    MD: Bombay University, India, 1985.

    Publications

    View PubMed Publications
    A photo of Larry Dolan.

    Lawrence M. Dolan, MD
    Director, Division of Endocrinology

    513-636-4744

    Lawrence M. Dolan, MD

    Director, Division of Endocrinology

    Director, Endocrinology Clinical Laboratory

    Professor, UC Department of Pediatrics

    Phone: 513-636-4744

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    Specialties

    Epidemiology and genetics of obesity; insulin resistance; abnormal carbohydrate metabolism; diabetes and their relationships to the development and progression of cardiovascular disease 

    Biography

    Lawrence M. Dolan, MD, is board-certified in pediatrics and pediatric endocrinology. He has been on the faculty of Cincinnati Children's Hospital Medical Center in the Department of Pediatrics for the University of Cincinnati College of Medicine since 1983.

    Dr. Dolan is a professor of pediatrics in the Division of Endocrinology. His research focuses on the epidemiology and genetics of obesity, insulin resistance, abnormal carbohydrate metabolism, diabetes and their relationships to the development and progression of cardiovascular disease.

    Dr. Dolan received his bachelor of science degree from the University of San Francisco. He received his doctor of medicine degree from the University of California at Los Angeles.

    Dr. Dolan completed his pediatric internship and residency at the University of Minnesota. He also served as chief resident. He obtained fellowship training in pediatric endocrinology at the University of Virginia.

    Education and Training

    BS: University of San Francisco, San Francisco, CA, 1971.

    MD: University of California at Los Angeles, Los Angeles, CA, 1976.

    Residency: University of Minnesota, Minneapolis, MN, 1976 to 1979. Chief Resident, 1979.

    Fellowship: University of Virginia, Charlottesville, VA.

    Certification: Pediatrics, 1982; Pediatric Endocrinology, 1983.

    Publications

    View PubMed Publications

    Grants

    Understanding Social Status Input on Adolescent Health. Co-Principal Investigator. National Institutes of Health. Dec 2007 - Nov 2011. #RO1HD41527.

    SEARCH Nutritional Ancillary Study of the SEARCH for Diabetes in Youth Study. Co-Principal Investigator. National Institutes of Health. Feb 2008 - Jan 2012. #RO1DK077949.

    SEARCH 3: Cohort Study to assess the incidence of acute and chronic diabetes related complications. Principal Investigator. National Institutes of Health. Sep 2010 - Oct 2015. #1U18DP002709.

    Accelerated Cardiovascular Aging in Youth. Co-Principal Investigator. National Institutes of Health. Jan 2011 -Dec 2015. #R01-105591.

    A photo of Lesley A. Doughty.

    Lesley A. Doughty, MD
    Physician, Division of Critical Care Medicine

    513-636-4259

    lesley.doughty@cchmc.org

    Lesley A. Doughty, MD

    Physician, Division of Critical Care Medicine

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4259

    Fax: 513-636-4267

    Email: lesley.doughty@cchmc.org

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    Specialties

    Sepsis; multiple organ failure; viral immunomodulation

    Education and Training

    MD: Dartmouth Medical School.

    Residency: Tripler Army Medical Center.

    Fellowship: Children's Hospital of Pittsburgh.

    Publications

    View PubMed Publications
    A photo of Lisa Filipovich.

    Alexandra H. Filipovich, MD
    Ralph J. Stolle Chair, Clinical Immunology

    513-803-3218

    lisa.filipovich@cchmc.org

    Alexandra (Lisa) H. Filipovich, MD

    Ralph J. Stolle Chair, Clinical Immunology

    Director, Immune Deficiency and Histiocytosis Program

    Medical Director, Diagnostic Immunology Laboratory

    Professor, UC Department of Pediatrics

    Phone: 513-803-3218

    Fax: 513-636-3549

    Email: lisa.filipovich@cchmc.org

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    Specialties

    Clinical Interests

    Primary immunodeficiencies; BMT for primary immunodeficiencies; hemophagocytic lymphocytosis; post-BMT immune reconstruction 

    Research Interests

    Biology and genetics of hemophagocytic lymphohistiocytosis; investigation of hematopoietic cell transplantation for genetic immunodeficiencies; immunoreconstitution following pediatric stem cell transplantation 

    Biography

    Lisa Filipovich, MD, began her career at the University of Minnesota where she received her medical degree in 1974 and completed fellowships in both immunopathology and pediatric immunology. She became a professor of pediatrics and served for 10 years as the head of the Division of Immunology at the University of Minnesota Medical School. Dr. Filipovich came to Cincinnati Children’s in 1996. She is currently the Ralph J. Stolle Chair in Clinical Immunology and the director of the Immune Deficiency and Histiocytosis program. She also serves as the medical director of the Diagnostic Immunology Laboratory at Cincinnati Children’s.

    Dr. Filipovich has a special interest in histiocytic disorders, especially hemophagocytic lymphohistiocytosis (HLH). Other interests include bone marrow transplant for primary immune deficiencies and post-BMT immune reconstitution. She serves as president of the Histiocyte Society, an international group of more than 200 physicians and scientists who are committed to improving the lives of patients with histiocytosis through research.

    Education and Training

    MD: University of Minnesota, Minneapolis, MN, 1974.

    Residency: University of Minnesota Hospitals, Minneapolis, MN 1975-1978.

    Fellowship: Immunopathology, Departments of Pediatrics, Laboratory Medicine and Pathology, University of Minnesota 1978-1979.

    Fellowship: Pediatric Immunology, Department of Pediatrics, University of Minnesota 1979-1980.

    Certification: Pediatrics, 1980.

    Publications

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    Grants

    Gene Therapy for SCID-X1 Using Self-Inactivating Gamma. Principal Investigator. National Institutes of Health. Sep 2010 - Aug 2015. #U01 AI 087628.

    Rare Diseases Clinical Consortia for the Rare Diseases. Principal Investigator. National Institutes of Health. Sep 2009 - Aug 2014. #U54 AI 082973.

    Hypoxia and potassium channel activity in T Lymphocytes. Principal Investigator. National Institutes of Health. Jun 2009 - Jun 2014. #R01 CA 095286.

    Histiocyte Society Annual Meeting to be Held in Boston. Principal Investigator. National Institutes of Health. Feb 2011 - Jan 2012. #R13 HL 106925.


    Edward H. Giannini, MSc, DrPH

    Professor, UC Department of Pediatrics

    Phone: 513-636-7634

    Email: edward.giannini@cchmc.org

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    Publications

    View PubMed Publications
    A photo of Tracy Glauser.

    Tracy A. Glauser, MD
    Associate Director, Cincinnati Children's Research Foundation

    513-636-4222

    tracy.glauser@cchmc.org

    Tracy A. Glauser, MD

    Associate Director, Cincinnati Children's Research Foundation

    Director, Comprehensive Epilepsy Center

    Co-Director, Genetic Pharmacology Service

    Professor, UC Department of Pediatrics

    Phone: 513-636-4222

    Fax: 513-636-3980

    Email: tracy.glauser@cchmc.org

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    Specialties

    Clinical Interests

    Epilepsy; pharmacogenetics; clinical pharmacology

    Research Interests

    Clinical pharmacology; pharmacogenetics; antiepileptic clinical trials 

    Biography

    Tracy A. Glauser, MD, is professor of Pediatrics, director of the Comprehensive Epilepsy Center and co-director of the Genetic Pharmacology Service at Cincinnati Children’s Hospital Medical Center. Dr. Glauser received his medical degree, cum laude, from Jefferson Medical College in Philadelphia, PA. He completed his residency in pediatrics at the John Hopkins Hospital in Baltimore, MD, and fellowship in child neurology at The Children’s Hospital of Philadelphia, University of Pennsylvania in Philadelphia, PA. Dr. Glauser completed a National Institute of Neurological Disorders and Stroke research fellowship in pediatric neurology and was a fellow in epilepsy and electroencephalography at St. Louis Children’s Hospital, Washington University School of Medicine in St. Louis, Missouri.

    Dr. Glauser has authored and co-authored more than 130 articles and book chapters, been involved with the development of 6 evidence based guidelines about epilepsy therapy and given over 150 invited lectures throughout the world. He has been the principal investigator on multiple NIH grants. Currently, Dr. Glauser directs the NIH funded Childhood Absence Epilepsy clinical trial involving 32 pediatric centers around the United States. Dr. Glauser’s fields of expertise are pediatric neurology, pediatric epilepsy, clinical pharmacology and pharmacogenetics.

    Education and Training

    MD: Jefferson Medical College, Philadelphia, PA, 1985.

    Residency: Johns Hopkins Hospital, Baltimore, MD.

    Fellowship: St. Louis Children's Hospital, St. Louis, MO.

    Certification: Pediatrics, 1990; Neurology (with special competence in child neurology), 1991.

    Publications

    View PubMed Publications

    Grants

    Sodium channel gene variation in the treatment of epilepsy. Collaborator. Apr 2009 - Mar 2014. #R01NS062756.

    The epilepsy phenome/ genome project (EPGP). Pharmacogenetics Core/Site Principal Investigator. May 2007- Apr 2012. #R01NS053998.

    Gregory A. Grabowski, MD

    Adjunct Professor, UC Department of Pediatrics

    Phone: 513-636-7290

    Fax: 513-636-2261

    Email: greg.grabowski@cchmc.org

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    Specialties

    Clinical Interests

    Lysosomal storage diseases; molecular enzymology; gaucher disease; Fabry disease; molecular pathogenesis

    Research Interests

    Molecular pathogenesis and therapy of human genetic disease

    Education and Training

    MD: University of Minnesota Medical School, Minneapolis, MN, 1970 to 1974.

    Residency: University of Minnesota, Minneapolis, MN, 1974 to 1976.

    Fellowship: University of Minnesota, Minneapolis, MN, 1976 to 1979.

    Certification: American Board of Pediatrics, 1980; American Board of Medical Genetics; Clinical Genetics, 1987; Clinical Biochemical Genetics, 1987; Clinical Molecular Genetics, 1993.

    Publications

    View PubMed Publications.
    A photo of Jacqueline M. Grupp-Phelan.

    Jacqueline M. Grupp-Phelan, MD, MPH
    Director of Research, Division of Emergency Medicine

    513-636-7966

    jackie.grupp-phelan@cchmc.org

    Jacqueline M. Grupp-Phelan, MD, MPH

    Director of Research, Division of Emergency Medicine

    Associate Director, Division of Emergency Medicine

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-7966

    Fax: 513-636-7967

    Email: jackie.grupp-phelan@cchmc.org

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    Specialties

    Clinical Interests

    Pediatric emergency medicine

    Research Interests

    Mental health services research

    Biography

    Jaqueline Grupp-Phelan, MD, MPH, graduated from the University of Cincinnati College of Medicine. After completing her pediatric residency and emergency medicine fellowship at Children’s Memorial/Northwestern in Chicago, she moved to Tuba City on the Navajo Reservation where her interest in mental illness developed. Dr. Grupp-Phelan then completed a Master in Public Health in Seattle before coming back to Cincinnati Children’s. Her research interests include screening and interventions for mothers and children with mental illness in the Pediatric Emergency department. Dr. Grupp-Phelan recently completed a Career Development award from the National Institute of Mental Health and holds the Ruddy Chair for Pediatric Emergency Medicine Research, the first chair devoted to research in the Pediatric Emergency Department.

    Education and Training

    MPH: Medicine, University of Washington School of Public Health and Services, Seattle, Wash, 1998. 

    MD: University of Cincinnati College of Medicine, Cincinnati, OH, 1990. 

    BA: History, University of Cincinnati, Cincinnati, OH, 1986. 

    Residency: Children's Memorial Hospital, Chicago, Ill., 1993.

    Fellowship: General Academic Pediatrics, Agency for Health Care Policy and Research Senior Research Fellow, Seattle, Wash., 1998; Pediatric Emergency Medicine, Children's Memorial Hospital, Chicago, Ill., 1995.

    Certification: Pediatrics, 1994; Pediatric Emergency Medicine, 1997.

    Publications

    View PubMed Publications

    A photo of Dr. John Harley.

    John B. Harley, MD, PhD
    Director, Rheumatology

    513-803-3665

    john.harley@cchmc.org

    John B. Harley, MD, PhD

    Director, Rheumatology

    Professor, UC Department of Pediatrics

    Phone: 513-803-3665

    Email: john.harley@cchmc.org

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    Publications

    View PubMed Publications

    Grants

    Molecular & Immunologic Analysis of the Pathobiology of Human Anthrax. Co-Principal Investigator. National Institute of Allergy and Infectious Diseases. Sep 2009 - Aug 2014. #AI062629-06.

    Genomics of Lupus. Principal Investigator. Aug 2009 - Jul 2014. #1 P01 AI083194-01.

    Oklahoma Autoimmunity Center of Excellence Project 2. Co-investigator. National Institute of Allergy and Infectious Diseases. May 2009 - Apr 2014. #1 U19 AI082714-01.

    Genome-Wide Association Study in African-Americans with Systemic Lupus Erythematosus. Principal Investigator. Department of Defense. Sep 2010- Aug 2013. #PR094002.

    Genomics of Lupus Associations in the Hispanic 12q24 Linkage. Principal Investigator. National Institutes of Health. Jun 2008 - Mar 2013. #5 P01 AR049084-07.

    Lupus Association with Signal Transducer and Activator of Transcription 4. Principal Investigator. US Department of Veterans Affairs. Apr 2008 - Mar 2012.

    Genetic Linkage in Lupus. Principal Investigator. National Institute of Allergy and Infectious Diseases. Feb 2010 - Jan 2012. #3 R37 AI024717-21S1.

    A photo of James Heubi.

    James E. Heubi, MD
    Director, Clinical Translational Research Center

    513-636-4415

    james.heubi@cchmc.org

    James E. Heubi, MD

    Director, Clinical Translational Research Center

    Co-Director, Center for Clinical and Translational Science and Training

    Associate Dean, Clinical and Translational Research

    Professor, UC Department of Pediatrics

    Phone: 513-636-4415

    Fax: 513-636-4695

    Email: james.heubi@cchmc.org

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    Specialties

    Clinical Interests

    Inflammatory bowel disease; cholestatic liver disease; malabsorption

    Research Interests

    Cholesterol absorption; cholesterol metabolism; inborn errors of bile acid metabolism; bone metabolism in health and disease; TPN-related cholestasis and its treatment

    Biography

    James E. Heubi, MD, has been a practicing pediatric gastroenterologist since 1979, when he joined the staff at Cincinnati Children's Hospital Medical Center.

    Dr. Heubi's practice includes the treatment of all disorders affecting the gastrointestinal tract, liver and biliary tract and pancreas.

    Dr. Heubi's areas of practice interests include liver disease and complications related to end-stage liver disease and liver transplantation and the management of patients with "short gut" or compromised gut function requiring prolonged enteral or parenteral nutritional support.

    Dr. Heubi is the Director of General Clinical Research Center at Cincinnati Children's and is the Associate Dean for Clinical Research, University of Cincinnati, College of Medicine.

    Education and Training

    MD: Indiana University School of Medicine, Indianapolis, IN, 1973.

    Residency: James Whitcomb Riley Hospital for Children, Indiana University, Indianapolis, IN, 1973 to 1975.

    Fellowship: Children's Hospital Medical Center, Cincinnati, OH, 1975 to 1978.

    Certification: Pediatric Gastroenterology and Nutrition, 1990.

    Publications

    View PubMed Publications

    Heidi J. Kalkwarf, PhD, RD

    Professor, UC Department of Pediatrics

    Phone: 513-636-3803

    Fax: 513-636-4402

    Email: heidi.kalkwarf@cchmc.org

    Show All

    Specialties

    Calcium and bone metabolism; establishing nutrient requirements; calcium metabolism during lactation; bone mineral acquisition in children

    Biography

    Heidi Kalkwarf, PhD, RD, is a nutritional epidemiologist whose research interest is in the development of dietary recommendations to optimize health, particularly bone health.

    She has conducted research, funded by the National Institutes of Health (NIH) and the United States Department of Agriculture (USDA), focusing on dietary calcium requirements of lactating women and the changes in bone density and in calcium metabolism that occur during lactation and after weaning. Dr. Kalkwarf's research has been published in the New England Journal of Medicine, and was used by the Institute of Medicine to establish the new dietary calcium intake recommendations for lactating women.

    Dr. Kalkwarf also is investigating the normal patterns of bone growth and development in children and adolescents. The goals of this work are to identify the short term and long term consequences of low bone density in childhood, identify children who are at risk for osteoporosis later in life and to identify interventions to reduce this risk.

    Dr. Kalkwarf came to Cincinnati Children's Hospital Medical Center as a postdoctoral fellow in 1990 and joined the faculty in 1993. She earned her master's and doctoral degrees in Nutritional Sciences at Cornell University in Ithaca, NY.

    Education and Training

    PhD: Cornell University; Ithaca, NY, 1991. 

    Postdoctoral Fellowship: Children's Hospital Medical Center, Cincinnati, Ohio, 1990-1993. 

    MNS: Cornell University, Ithaca, NY, 1983. 

    BS: Washington State University, Pullman, WA, 1980. 

    Certification: Registered Dietitian, 1983.

    Publications

    View PubMed Publications

    Grants

    Impact of peripubertal exposure to xenohormones on fat distribution and cytokines. Co-investigator. National Institutes of Health. Apr 2010 - Mar 2012. #R21 ES017315-01A1.

    Cincinnati Center for Clinical and Translational Sciences and Training Grant. Co-investigator. National Institutes of Health. Apr 2009 - Mar 2013. #UL1 RR026314-01.

    Co-investigator. National Institutes of Health. Apr 2009 - Mar 2013. #UL1 RR026314-01.

    Continued studies of environment impact on puberty. Co-investigator. National Institutes of Health. Sep 2001 - Apr 2015. #U01 ES019453-0.

    Genome Wide Association Study of Bone Mineral Accretion during Childhood.  Co-investigator (Principal investigator of sub-contract).National Institutes of Health. Fen 2010 - Jan 2015. #R01 HD058886-01A2.

    A photo of Uma Kotagal.

    Uma R. Kotagal, MBBS, MSc
    Senior Vice President, Quality, Safety and Transformation; Executive Director, James M. Anderson Center for Health Systems Excellence

    513-636-0178

    uma.kotagal@cchmc.org

    Uma R. Kotagal, MBBS, MSc

    Senior Vice President, Quality, Safety and Transformation; Executive Director, James M. Anderson Center for Health Systems Excellence

    Professor, UC Department of Pediatrics

    Phone: 513-636-0178

    Fax: 513-636-0171

    Email: uma.kotagal@cchmc.org

    Show All

    Specialties

    Outcomes research; outcomes and cost of early discharge of newborn care; cost effectiveness of neonatal intensive care; cost effectiveness of prenatal care

    Biography

    Uma Kotagal is senior vice president for quality, safety and transformation and executive director of the James M. Anderson Center for Health Systems Excellence at Cincinnati Children’s Hospital Medical Center.

    As director of the Anderson Center, Dr. Kotagal oversees the development of disease management teams and development and institution of evidence-based clinical practice guidelines.

    The primary purpose of the Anderson Center is to foster health services research and system transformation with the goal of improving the quality of healthcare delivery, translating knowledge into practice, and building the next generation of improvement leaders.

    Dr. Kotagal was director of the neonatal intensive care units at the University Hospital and at Cincinnati Children’s for several years. While practicing, Dr. Kotagal recognized that care and outcomes improvement were a system property. She completed additional training, receiving her master’s of science in clinical epidemiology and clinical effectiveness from the Harvard School of Public Health, and refocused her clinical efforts on quality transformation at a systems level. She was also a visiting scholar at the Center for Risk Analysis at the Harvard School of Public Health and a visiting professor at the Tufts New England Medical Center, in the Division of Clinical Decision Making, completing further training in the field of decision and cost effectiveness analyses.

    Dr. Kotagal has published extensively in the field of neonatal outcomes research, including studies on neonatal cost models, and early discharge of newborns. She published the first landmark paper on early discharge programs in the NICU setting.

    Dr. Kotagal was born in Bombay, India, where she received her undergraduate and her MBBS from the University of Bombay. She did a rotating internship at the University of Bombay from 1970-1971 and another rotating internship at Detroit General Hospital from 1971-1972.

    At Children’s Hospital of Michigan, Dr. Kotagal completed her pediatric residency from 1972-1974 and went on to do a fellowship in neonatology from 1974-1975. She completed a fellowship in neonatal physiology at the University of Cincinnati from 1975-1977.

    Dr. Kotagal is a senior faculty member of the Institute for Healthcare. She also serves as chair of the quality steering team of the Ohio Children’s Hospital Association, as a member of the advisory committee of the Toronto Patient Safety Center, as an associate editor of BMJ Quality and Safety and as a member of the Institute of Medicine.

    Dr. Kotagal is also a member of various local, regional and national committees in the area of child health.

    Education and Training

    MBBS: Grant Medical College, University of Bombay, Bombay, India, 1970. 

    MSc: Harvard School of Public Health, Boston, MA, 1996.

    Residency: Children's Hospital of Michigan, Detroit, MI.

    Fellowship: Neonatology, Children's Hospital of Michigan, Detroit, MI; Neonatal Physiology, University of Cincinnati College of Medicine, Cincinnati, OH.

    Certification: Pediatrics, 1975; Neonatal-Perinatal Medicine, 1977.

    Publications

    View PubMed Publications

    A photo of Daniel Lovell.

    Daniel J. Lovell, MD, MPH
    Associate Director, Division of Rheumatology

    513-636-4676

    daniel.lovell@cchmc.org

    Daniel J. Lovell, MD, MPH

    Associate Director, Division of Rheumatology

    Professor, UC Department of Pediatrics

    Phone: 513-636-4676

    Fax: 513-636-5990

    Email: daniel.lovell@cchmc.org

    Show All

    Specialties

    Clinical Interests

    Diagnostic evaluation and ongoing care of children with all pediatric onset rheumatic diseases

    Research Interests

    Performance of clinical trials in children with rheumatic diseases; clinical trials methodology; mentoring of junior faculty

    Education and Training

    MD: University of Kansas, Kansas City, Kan., 1978. 

    MPH: University of Texas School of Public Health, Houston, Texas, 1982. 

    Residency: Children's Mercy Hospital, Kansas City, Kan. 

    Fellowship: Baylor College of Medicine, Houston, Texas. 

    Certification: Pediatrics, 1984; Pediatric Rheumatology, 1992.

    Publications

    View PubMed Publications
    A photo of Mark Mitsnefes.

    Mark M. Mitsnefes, MD, MS
    Director, Clinical and Translational Research Center

    513-636-0125

    mark.mitsnefes@cchmc.org

    Mark M. Mitsnefes, MD, MS

    Director, Clinical and Translational Research Center

    Pediatric Nephrologist

    Professor, UC Department of Pediatrics

    Phone: 513-636-0125

    Fax: 513-636-7407

    Email: mark.mitsnefes@cchmc.org

    Show All

    Specialties

    Nephrology with focus on chronic kidney disease and hypertension

    Biography

    Mark Mitsnefes, MD, MS, is an established clinical investigator with expertise in the area of understanding the development of risk factors for cardiovascular disease in children with chronic kidney disease. The long-term goal of his research is to define biologic targets for interventions to prevent and slow progression of cardiovascular disease in children with chronic kidney disease.

    Dr. Misnefes has received numerous awards, including the Proctor Scolar Award (Cincinnati Children's Research Foundation), the Pediatrician Scientist Award (Children's Health Research Center, NIH), the Clinical Scientist Award (National Kidney Foundation), and has been ranked as one of the Best Doctors in America, 2007-2011.

    Education and Training

    MD: Gorky Medical Institute, Gorky, Russia, 1985.

    Residency: Miami Children's Hospital, Miami, Florida, 1997.

    Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2000.

    MS: Epidemiology and Biostatistics, University of Cincinnati, Cincinnati, Ohio, 2001.

    Certifications: Educational Commission for Foreign Medical Graduates (ECFMG), 1995; Pediatrics, 1996; Pediatric Nephrology, 2001, 2008.

    Publications

    View PubMed Publications

    Grants

    Adiponectin and Cardiovascular Disease in the CKiD Children. Principal Investigator. National Institutes of Health. 2007 - 2011. #R01 DK076957.

    Modify Dietary Behavior in Adolescents with Elevated Blood Pressure. Co-investigator. National Institutes of Health. 2007 - 2012.

    Prospective study of chronic kidney disease in children. Co-investigator, Co-chair of the Cardiovascular Committee. National Institutes of Health. 2003 - 2013. #U01 DK-03-012.

    Cardiovascular disease in children with CKD. Principal Investigator. National Institutes of Health. 2011 - 2016. #K24 DK090070-01.


    A photo of Ardythe Morrow.

    Ardythe L. Morrow, PhD
    Director, Center for Interdisciplinary Research in Human Milk & Lactation

    513-636-7584

    ardythe.morrow@cchmc.org

    A photo of Ardythe Morrow.

    Ardythe L. Morrow, PhD

    Director, Center for Interdisciplinary Research in Human Milk & Lactation

    Professor, UC Department of Pediatrics

    Phone: 513-636-7584

    Email: ardythe.morrow@cchmc.org

    Show All

    Specialties

    Human milk; child health and nutrition

    Biography

    Dr. Morrow received her MSc in nutrition from the University of the West Indies, Kingston, Jamaica (1980) and PhD in epidemiology from the University of Texas at Houston (1991). Since 1987 she has worked with colleagues in Mexico, Boston, and Houston on an NIH-funded program project on human milk immune protection against infectious disease.

    She is currently Professor of Pediatrics at the University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center, where she founded and directs the Center for Epidemiology and Biostatistics that has 35 faculty and staff and a multi-disciplinary Human Milk Research Program that includes clinical and basic science investigators in eight divisions.

    She has published extensively on breastfeeding promotion and human milk protection against infectious diseases. Her primary focus is on protection by human milk glycans and protection against infectious disease, but she has expanded her research to understanding the relationship between breastfeeding and chronic diseases. She has been an ad hoc reviewer for NIH on breastfeeding research and a technical advisor for international breastfeeding policy and programs for Gates Foundation, UNICEF, and WHO, is on the editorial board of the Journal of Human Lactation and the journal of the Academy of Breastfeeding Medicine. She is an elected member of the American Pediatric Society. She has over 100 publications, and is the primary author of the WHO monograph, Community-based Strategies for Breastfeeding Promotion and Support in Developing Countries (2004).

    She has served as Chair of the Milk Club of the (American) Society for Pediatric Research for the past 4 years. In 1997, she received a Young Investigator award from ISRHML for her randomized trial of breastfeeding support (Lancet, 1999). She was co-organizer of the 2002 ISRHML international meeting in Mexico and is co-editor of the book Protecting Infants through Human Milk: Advancing the Scientific Evidence.

    Education and Training

    BA: Rice University, Houston, Texas.

    MSc: University of the West Indies, Kingston, Jamaica.

    PhD: The University of Texas School of Public Health, Houston, Texas 1991.

    Publications

    View PubMed Publications
    A photo of Marc Rothenberg, MD, PhD.

    Marc E. Rothenberg, MD, PhD
    Director, Division of Allergy and Immunology

    513-803-0257

    marc.rothenberg@cchmc.org

    Marc E. Rothenberg, MD, PhD

    Director, Division of Allergy and Immunology

    Director, Cincinnati Center for Eosinophilic Disorders

    Program Director, CHRCDA (K12)

    Professor, UC Department of Pediatrics

    Phone: 513-803-0257

    Fax: 513-636-3310

    Email: marc.rothenberg@cchmc.org

    Show All

    Specialties

    Clinical Interests

    Eosinophilia; eosinophilic disorders; asthma; allergy; food allergy

    Research Interests

    Eosinophils; chemokines

    Visit the Rothenberg Lab.

    Biography

    Marc E. Rothenberg, MD, PhD, is the Director of the Division of Allergy and Immunology at Cincinnati Children's Hospital Medical Center, and a tenured Professor of Pediatrics at Cincinnati Children’s and the University of Cincinnati College of Medicine. He graduated summa cum laude with Highest Honors in Chemistry and Biochemistry from Brandeis University. He then matriculated at Harvard Medical School in the combined MD / PhD program. His PhD under the mentorship of Dr. Frank Austen included seminal studies on eosinophil hematopoiesis, as he developed the first culture system for human eosinophils.

    After completing a two-year residency in pediatrics at Children’s Hospital in Boston, Dr. Rothenberg did a combined fellowship in allergy / immunology and hematology at Children’s Hospital in Boston. During this fellowship program, Dr. Rothenberg did post-doctorate training in the genetics laboratory of Dr. Philip Leder at Harvard Medical School, where he cloned the eotaxin chemokine. After being on faculty of Harvard Medical School for one year, he came to the University of Cincinnati and Cincinnati Children's, one of the largest pediatric medical and research centers in the United States. He is actively involved in managing a research program focused on understanding the molecular mechanisms of allergic disorders. At Cincinnati Children’s, he has helped build a top program in pediatric research, and his division is a leader in pediatric allergy and immunology. In addition, he sees patients suffering from allergic and immunological diseases from around the world as part of the Cincinnati Center for Eosinophilic Disorders that he directs.

    Dr. Rothenberg’s awards include the Pharmacia Allergy Research Foundation Award for the best young investigator in the allergy field; the Young Investigator Award and the Scholar in Allergy Award from the American Academy of Allergy, Asthma, and Immunology; the Ohio Governor’s Recognition Award; the 2007 E Mead Johnson Award from the Society of Pediatric Research; and an NIH MERIT Award in 2010 from the NIAID. He is an elected member of the American Society of Clinical Investigation, Society for Pediatric Research, and a Diplomate of the American Academy of Allergy, Asthma and Immunology.

    Among his extensive publications of more than 250 articles on molecular mechanisms of allergic responses, Dr. Rothenberg edited a book entitled, “Chemokines in Allergic Disease”. He has served on various review panels for journals and grant agencies including the National Institutes of Health, where he served on the Advisory Council of the NIAID, Burroughs Trust, and the Medical Research Council of the UK. His research has been supported by numerous sources including the National Institutes of Health, the USA Department of Defense, Human Frontier Science Program Organization, the Burroughs Wellcome Fund, the Dana Foundation, and the Food Allergy and Anaphylaxis Network.

    Visit the Rothenberg Lab website

    Education and Training

    MD, PhD: Harvard Medical School, Cambridge, MA, 1990.

    Residency: Pediatrics, Children's Hospital, Boston, MA, 1991-1992.

    Fellowship: Immunology / Allergy, Children's Hospital, Boston, MA, 1992-1994; Hematology / Oncology, Children's Hospital and Dana Farber Cancer Institute, Boston, MA, 1992-1995.

    Certification: National Board of Medical Examiners, 1991; Board of Registration in Medicine, MA, 1992; American Board of Pediatrics, 1995, 2001, 2008; Ohio State Medical Board, 1997; American Board of Allergy and Immunology, 1997, 2006.

    Publications

    Grants

    NICHHD Pediatric Center for Gene Expression and Developmental Sciences. Program Director. National Institutes of Health. 2007-2011. K12 HD028827.

    IL-13 and Eosinophilic Esophagitis. Principal Investigator. National Institutes of Health.  2007-2012. R01 DK076893.

    Genetics of Eosinophilic Esophagitis. Principal Investigator. Department of Defense. 2010-2012. DOD W81XWH1010167. 

    Resistin-like Molecules in the Lung. Co-Principal Investigator. US-Israel Binational Science Foundation. 2010-2012. #2009222. 

    IL-13 Associated Eosinophil Lung Responses. Principal Investigator. National Institutes of Health. 2009-2014. R01 AI083450.

    Regulation of Gastrointestinal Eosinophils. Principal Investigator. National Institutes of Health. 2009-2014. R37 AI045898. 


    A photo of Lori Stark.

    Lori J. Stark, PhD, ABPP
    Director, Behavioral Medicine and Clinical Psychology

    513-636-4336

    Lori J. Stark, PhD, ABPP

    Director, Behavioral Medicine and Clinical Psychology

    Professor, UC Department of Pediatrics

    Phone: 513-636-4336

    Fax: 513-636-3677

    Show All

    Specialties

    Biography

    Lori Stark, PhD, joined Cincinnati Children's Hospital Medical Center in 1998 as the director of Psychology.

    Dr. Stark is an authority on parenting of young children. She has applied this expertise to the area of health psychology by working with parents and children to improve their adherence to medical regimes, improving coping with chronic conditions or acute stressors, and providing biobehavioral interventions to conditions such as chronic pain.

    Dr. Stark's work is unique in that it utilizes behavioral and environmental interventions to enhance healthcare outcome in pediatrics. Dr. Stark's expertise is on improving nutritional outcome in children with chronic conditions such as cystic fibrosis.

    Dr. Stark has received continuous funding from the Cystic Fibrosis Foundation and the National Institute of Health to develop and evaluate behavioral interventions and improving nutritional outcome in children with cystic fibrosis.

    Dr. Stark came to Cincinnati Children's Hospital Medical Center from Brown University School of Medicine where she was director of Pediatric Psychology at Rhode Island Hospital and associate professor of Psychiatry in Human Behavior at Brown University School of Medicine. Dr. Stark earned her undergraduate degree at Boston University and her graduate degree at West Virginia University.

    Dr. Stark is on the Executive Committee of the Society of Pediatric Psychology, a division within the American Psychological Association. She has written many professional publications in the field of pediatric psychology and serves on the editorial board of the Journal of Pediatric Psychology and the Journal of Applied Behavior Analysis.

    Education and Training

    PhD: West Virginia University, Morgantown, WV, 1985.

    Internship: Clinical Psychology, University of Mississippi Medical Center, Jackson, MS, 1984-1985.

    Certification: Clinical Psychology, 1985.

    A photo of Mark Steinhoff.

    Mark C. Steinhoff, MD
    Director, Global Health Center

    513-636-1376

    mark.steinhoff@cchmc.org

    Mark C. Steinhoff, MD

    Director, Global Health Center

    Professor, UC Department of Pediatrics

    Phone: 513-636-1376

    Fax: 513-803-0903

    Email: mark.steinhoff@cchmc.org

    Show All

    Education and Training

    MD: University of Chicago, Chicago, Illinois, 1973.

    Residency and Chief Residency: Pediatrics, University of Rochester Medical Center, Rochester, New York.

    Fellowship, Infectious Diseases: University of Rochester Medical Center, Rochester, New York.

    Certification: New York State Medical License, 1976; Pediatrics, 1978; Tamil Nadu Medical Council (India), 1980; Michigan Medical License, 1985; Maryland Medical License, 1986; Ohio Medical License, 2010; Pediatric Infectious Diseases Society, 1988.

    Publications

    View PubMed Publications

    A photo of Bruce Trapnell.

    Bruce C. Trapnell, MS, MD
    Assistant Director, Adult Cystic Fibrosis Center

    513-636-6361

    bruce.trapnell@cchmc.org

    Bruce C. Trapnell, MS, MD

    Assistant Director, Adult Cystic Fibrosis Center

    Attending Physician

    Pulmonologist - Research, Adult Clinical, Division of Pulmonary Medicine

    Professor, UC Department of Pediatrics

    Phone: 513-636-6361

    Fax: 513-636-3723

    Email: bruce.trapnell@cchmc.org

    Show All

    Specialties

    Clinical Interests

    Pulmonary alveolar proteinosis; cystic fibrosis; alpha-1 antitrypsin deficiency; other rare lung disorders

    Research Interests

    Alveolar macrophage function; molecular techniques using gene knockout, transgenic and conditional gene expression mouse models and non-human primates, in vitro and in vivo viral gene transfer, and bone marrow transplantation

    Biography

    Bruce Trapnell, MS, MD received his medical degree from the University of Maryland in 1985, and completed a medical residency at The Ohio State University Hospitals and a fellowship in pulmonary medicine at the Clinical Center of the National Institutes of health, where he then served as Senior Attending Physician. Subsequently, he established the Division of Pulmonary and Virology Studies at Genetic Therapy, Inc., a subsidiary of Novartis, Pharma, serving as Vice President before joining Cincinnati Children’s Hospital Medical Center, where he is now Full Professor.

    Dr. Trapnell has conducted lung disease research since his training and has been continuously funded by the NIH since 2001, shortly after his arrival in Cincinnati. He has published over 90 original articles and has trained more than 16 post-doctoral fellows. Dr. Trapnell’s research interests are focused to the pathogenesis and therapy of rare lung diseases and mechanisms by which GM-CSF regulates innate immunity and lung host defense.

    Dr. Trapnell is Director of Cincinnati’s Cystic Fibrosis Therapeutics Development Network Center, Assistant Director of the Adult Cystic Fibrosis Care Center, Director of the Rare Lung Diseases Clinical Research Consortium, Scientific Director of the Pulmonary Alveolar Proteinosis Foundation. Dr. Trapnell is the past Scientific Director of the Alpha-1 Foundation, for which he organized and directed the grant program for eight years.

    Education and Training

    MS: Genetics, The George Washington University, Washington, DC, 1981.

    MD:
    University of Maryland School of Medicine, Baltimore, MD, 1984.

    Residency: Internal Medicine, The Ohio State University Hospitals, Columbus, OH, 1987.

    Fellowship: Pulmonary Medicine, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD, 1989.

    Certification: Diplomate in Internal Medicine, American Board of Internal Medicine, 1987; Diplomate, National Board of Medical Examiners, 1987; Diplomate in Pulmonary Medicine, American Board of Internal Medicine, 2000 .

    Publications

    View PubMed Publications

    Grants

    Role of Anti-GM-CSF Antibodies in Myeloid Cell Function & Innate Immunity. Principal Investigator. National Institutes of Health. Apr 2007 - Mar 2012. #R01 HL085453-01A1. 
    A photo of Elaine Urbina.

    Elaine M. Urbina, MD, MS
    Director, Preventive Cardiology

    513-636-8265

    lipid_htm@cchmc.org

    Elaine M. Urbina, MD, MS

    Director, Preventive Cardiology

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-8265

    Fax: 513-636-0162

    Email: lipid_htm@cchmc.org

    Show All

    Specialties

    Pediatric high blood pressure and cholesterol, diet and exercise to prevent adult heart disease

    Biography

    Elaine M. Urbina, MD, graduated from the Medical College of Georgia in 1988. She subsequently trained in pediatrics at the University of California at San Francisco. She completed her pediatric cardiology fellowship at Tulane University in New Orleans, Louisiana, in 1994 where she accepted an assistant professor position.

    In addition to practicing clinical pediatric cardiology at Tulane, she was also director of preventive cardiology and the Pediatric Echocardiography Laboratory. Her research interests led her to join the world-renowned Bogalusa Heart Study, one of the longest running epidemiologic studies of CV risk factors in children. As co-investigator under the tutelage of Dr. Gerald S. Berenson, she initiated the non-invasive imaging program and supervised collection of CV data for over a decade.

    Dr. Urbina joined Cincinnati Children's Hospital Medical Center as associate professor in October of 2003 and became director of preventive cardiology in 2006. This new opportunity allowed her to concentrate her clinical practice on the diagnosis and treatment of high blood pressure and cholesterol. She continues her research studies concentrating on non-invasive imaging methods to measure atherosclerosis with a focus on vascular function abnormalities using the modalities of:

    • Carotid Ultrasound
    • Arterial Stiffness
    • Endothelial Function

    Her current research includes the application of these new techniques to study the roles that pre- and post-natal nutrition, overweight, high blood pressure, cholesterol and diabetes play in the development of hardening of the arteries.

    Education and Training

    MD: Medical College of Georgia, Augusta, GA, 1988.

    Residency: University of California, San Francisco, CA, 1990; Tulane University, New Orleans, LA 1991 (Pediatrics).

    Fellowship: Tulane University, New Orleans, LA, 1994 (Pediatric Cardiology).

    Certification: Pediatrics 1991; Pediatric Cardiology 1994.

    Publications

    View PubMed Publications

    Grants

    Accelerated CV Aging in Youth Related to CV Risk Factor Clusters. Principal Investigator. National Heart, Lung and Blood Institute. Jan 2011-Dec 2016.

    SEARCH 3: Cohort Study - Ohio site. Co-Investigator. Centers for Disease Control & National Institutes of Health. Sept 2010-Oct 2015.

    Cardiovascular Effects of Dietary Fat & Exercise Challenges in Obese Children. Collaborator. National Heart, Lung and Blood Institute. June 2008-May 2013.

    Modifying Dietary Behavior in Adolescents with Elevated Blood Pressure. Co-Investigator. Natonal Heart, Lung and Blood Institute. Dec 2007-Nov 2012.


    A photo of Basilia Zingarelli.

    Basilia Zingarelli, MD, PhD
    Director, Basic Science Research

    513-636-8704

    basilia.zingarelli@cchmc.org

    Basilia Zingarelli, MD, PhD

    Director, Basic Science Research

    Professor, UC Department of Pediatrics

    Phone: 513-636-8704

    Email: basilia.zingarelli@cchmc.org

    Show All

    Specialties

    Sepsis; trauma; hemorrhagic shock and ischemia and reperfusion injury.
    Visit the Zingarelli Lab.

    Biography

    Basilia Zingarelli, MD, PhD, came to Cincinnati Children's Hospital Medical Center in 1995 as a post-doctoral research fellow in Critical Care Medicine. She joined the faculty in 1997.

    Dr. Zingarelli graduated from the Medical School of the University of Messina in Italy in 1990. She also obtained a doctorate in experimental medicine in 1997 and attended a residency in medical toxicology at the University of Messina from 1990 to 1992.

    Dr. Zingarelli now directs the basic science research in the Division of Critical Care Medicine. She directs an NIH-funded research laboratory focused on the pathogenetic mechanisms of organ injury during sepsis, trauma and hemorrhage and coordinates basic science and clinical translational research projects related to other critical care conditions.

    Dr. Zingarelli serves on the Executive Council of the Shock Society, a well-established international association of clinical and research scientists in the field of shock and trauma, and serves as associate editor for the journal Shock. She also serves as permanent and ad hoc member on a number of study sections at the National Institutes of Health.

    Education and Training

    MD: School of Medicine, University of Messina, Italy, 1990.

    PhD: Experimental Medicine, School of Medicine, University of Messina, Italy, 1997.

    Residency: Medical Toxicology, School of Medicine, University of Messina, Italy, 1990-1992.

    Certification: General Medicine (Italian), 1990.

    Publications

    View PubMed Publications

    Grants

    Role of Eicosanoids In Shock. Co-Investigator. National Institutes of Health. Jul 2008 - Jun 2012. #R01 GM 027673.

    Mechanisms of Age-Related Inflammatory Response in Hemorrhagic Shock. Principal Investigator. National Institutes of Health. Sep 2007 - Aug 2012. #R01 AG 027990.

    Host response to trauma research training program. Faculty/mentor. National Institutes of Health (T32 GM08478). Jul 2003-Jun 2013.

    Interferon-mediated reprogramming of Toll-like receptor signaling. Co-Investigator. National Institutes of Health. Jul 2008 - Jun 2013. #R01 GM085063.

    Role of PPARgamma and PPARgamma Agonists in Septic Shock. Principal Investigator. National Institutes of Health. Jul 2008 - Jun 2013. #R01 GM 067202.

    MMP-8 as a novel therapeutic target in sepsis. Co-Investigator. National Institutes of Health. Jul 2011 - Jun 2015. #R01 GM096994.