Infectious Diseases

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    Faculty

    A photo of David Bernstein.

    David I. Bernstein, MD, MA
    Director, Gamble Program and VTEU

    513-636-7625

    david.bernstein@cchmc.org

    David I. Bernstein, MD, MA

    Director, Gamble Program and VTEU

    Professor, UC Department of Pediatrics

    Phone: 513-636-7625

    Fax: 513-636-7682

    Email: david.bernstein@cchmc.org

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    Specialties

    Clinical Interests

    Rotavirus; herpes simplex virus; cytomegalovirus; preclinical and clinical evaluations of vaccine; immune response to herpes virus

    Research Interests

    Evaluation of vaccines and antivirals for herpes and rotovirus; development of improved adjuvants and delivery systems for vaccines; treatment and prevention of influenza, norovirus and parvovirus infections

    Biography

    Dr. Bernstein received his MA degree in microbiology and his MD degree from SUNY at Buffalo. His pediatric training was undertaken at USC and the New England Medical Center. This was followed by an ID fellowship at UCLA.

    During his fellowship he became interested in herpes viruses and vaccines. Upon arrival at Cincinnati Children’s Hospital Medical Center he began his work investigating the immunobiology of genital herpes infections. At this time he also became interested in rotavirus and along with his colleague Dr. Richard Ward he investigated the immune responses that provide protection.

    This work led to the development of a live attenuated human rotavirus vaccine initially named 89-12. The 89-12 vaccine was further modified and became the GlaxoSmithKline rotavirus vaccine, Rotarix, currently available in over 100 countries including the USA and EU. Dr. Bernstein is currently evaluating vaccines for CMV, HSV, influenza, avian influenza, RSV, norovirus and parvovirus. Dr. Bernstein has published over 200 manuscripts and book chapters on infectious diseases, vaccines and antivirals. Dr. Bernstein is currently the Albert Sabin Professor of pediatrics and director of the Division of Infectious Diseases at Cincinnati Children’s and directs one of eight NIH funded Vaccine Evaluation Units.

    Education and Training

    MA: Microbiology, State University of New York at Buffalo, Buffalo, NY, 1973.

    MD: State University of New York at Buffalo School of Medicine, Buffalo, NY, 1977.

    Residency: Pediatrics, University of Southern California Medical Center, Los Angeles, CA; Tufts University School of Medicine, Boston, MA.

    Fellowship: Pediatric Infectious Disease, University of California, Los Angeles, CA.

    Certification: American Board of Medical Examiners, 1978; American Board of Pediatrics, 1981; Pediatrics, 1982.

    Publications

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    Grants

    Vaccine and Treatment Evaluation Units (VTEUs): Evaluation of Control Measures Against Diseases Other Than AIDS. Principal Investigator. 2007 - 2014. #NO1-AI-80006.

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    Rebecca C. Brady, MD
    Director, Adult Clinical Services

    513-636-4578

    rebecca.brady@cchmc.org

    No photo available

    Rebecca C. Brady, MD

    Director, Adult Clinical Services

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4578

    Email: rebecca.brady@cchmc.org

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    Specialties

    Clinical Interests

    Adult and pediatric infectious disease

    Research Interests

    Cytomegalovirus and other viral infections 

    Education and Training

    MD: University of Kentucky, Lexington, KY, 1988.

    Residency: Internal Medicine/Pediatrics, University of Louisville, Louisville, KY.

    Fellowships: Pediatric Infectious Diseases, Children's Hospital Medical Center, Cincinnati, Ohio; Adult Infectious Diseases, University of Cincinnati, Cincinnati, OH.

    Certifications: Pediatrics, 1992, recertified 1999; Internal Medicine, 1993; Pediatric Infectious Diseases, 1997; Adult Infectious Diseases, 1997.

    Publications

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    Rhonda Cardin, PhD

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-2420

    Email: rhonda.cardin@cchmc.org

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    Specialties

    The research focus of the Cardin lab is to understand the virus-host interactions that are important for CMV pathogenesis and immunological control of long term latent CMV infection. CMV encodes viral homologs to host proteins (such as IL-10, TNF, chemokine receptors) that interfere with the host immune response by immune evasion or by mimicry. Understanding the advantages provided by 'hijacking' of host proteins by CMV will lead to the development of effective vaccine strategies.

    Education and Training

    BA: Biology and Psychology, Washington University, St. Louis, Missouri, 1983.

    PhD: Microbiology, Louisiana State University, Baton Rouge, Louisiana, 1989.

    Publications

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    A photo of Beverly Connelly.

    Beverly L. Connelly, MD
    Director, Infection Control Program

    513-636-8492

    beverly.connelly@cchmc.org

    Beverly L. Connelly, MD

    Director, Infection Control Program

    Professor, UC Department of Pediatrics

    Phone: 513-636-8492

    Fax: 513-636-7598

    Email: beverly.connelly@cchmc.org

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    Specialties

    Education and Training

    MD: Medical College of Georgia, Augusta, Ga., 1979.

    Residency: Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio, 1979-1982.

    Fellowship: Pediatric Infectious Disease, Children's Hospital Medical Center, Cincinnati, Ohio, 1983-1986.

    Certification: Pediatrics, 1984; Pediatric Infectious Diseases, 1994, recertified, 2000.


    Lara A. Danziger-Isakov, MD, MPH

    Director, Transplant ID

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4578

    Email: lara.danziger-isakov@cchmc.org

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    Specialties

    Transplant infectious diseases

    Biography

    Dr. Danziger-Isakov began her research career investigating cytomegalovirus in pediatric lung transplant recipients. After completing fellowship she led an international epidemiological study of pediatric lung transplant recipients including 14 international sites from North America and Europe to publish seminal manuscripts on fungal and viral infections through the International Pediatric Lung Transplant Collaborative. While at the Cleveland Clinic she performed an innovative investigation evaluating alloreactive cellular and humoral responses to influenza vaccine in transplant recipients. She is the protocol chair for two NIH-funded pediatric transplant studies in the Clinical Trials in Organ Transplantation in Pediatrics (CTOT-C) entitled "Viral Triggers of Alloimmunity and Autoimmunity in Pediatric Lung Transplantation (CTOTC-03)" and "Perceived Barriers to Patient Adherence after Pediatric Solid Organ Transplantation (CTOTC-05)" with principal investigator Stuart Sweet at Washington University. 

    Dr. Danziger-Isakov is a member of several international organizations, with guest lectureships throughout the North America and Europe. She has been recognized with the Clinical Science Career Development Award from the American Society of Transplantation in 2012, has been elected as co-editor for the American Society of Transplantation’s 3rd Edition of the Infectious Diseases Guidelines, and served as Infectious Disease Council Chair for the International Society of Heart and Lung Transplantation.

    Education and Training

    MD: Case Western Reserve University, Cleveland, OH, 1997.

    MPH: Saint Louis University, St. Louis, MO, 2004.

    Residency: Pediatrics, Cleveland Clinic Foundation, Cleveland, OH, 1997-2000.

    Fellowship: Pediatric Infectious Diseases, St. Louis Children’s Hospital, Washington Univeristy, St. Louis, MO, 2000-2003.

    Certification: Pediatrics, 2000; Pediatric Infectious Diseases, 2003.

    Publications

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    Michelle P. Dickey, MS, CFNP, CPNP, CCRC

    Nurse Practitioner

    Field Service Instructor, Division of Infectious Diseases

    Instructor, UC Department of Pediatrics


    A photo of Robert W. Frenck Jr.

    Robert W. Frenck Jr., MD
    Medical Director, Division of Infectious Diseases

    513-803-3164

    robert.frenck@cchmc.org

    Robert W. Frenck Jr., MD

    Medical Director, Division of Infectious Diseases

    Professor, UC Department of Pediatrics

    Phone: 513-803-3164

    Fax: 513-636-3959

    Email: robert.frenck@cchmc.org

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    Specialties

    Clinical

    Vaccine research; enteric diseases; travel medicine

    Research

    Enteric diseases; vaccinology

    Biography

    Robert W. Frenck Jr., MD, received his undergraduate degree from the University of California at San Diego in 1977 followed by his doctor of medicine degree from the University of Texas Health Science Center at Houston in 1981. He trained at the National Naval Medical Center in Bethesda, Maryland, completing his pediatric residency in 1984. After three years as a general pediatrician at the US Naval Hospital, Japan, he entered pediatric infectious disease fellowship training at the University of Texas Health Science Center at Houston, which he completed in 1990. Dr. Frenck is board-certified in both pediatrics and infectious diseases.

    Dr. Frenck's research interests include therapeutic and vaccine clinical trials with special interest in enteric diseases. After completing a 25-year career in the Navy, Dr. Frenck joined the UCLA Center for Vaccine Research in 2004 and served until 2006 as director of the Center and a Professor of Pediatrics at UCLA School of Medicine. Dr. Frenck has been active in the American Academy of Pediatrics and currently serves on the Red Book Committee. He is an acknowledged authority in infectious diseases and has authored over 60 articles and book chapters on various aspects of this subject.

    Education and Training

    BA: University of California at San Diego, San Diego, CA, 1977. 

    MD: University of Texas Medical School at Houston, Houston, TX, 1981. 

    Internship and Residency: US Naval Hospital, Bethesda, MD, 1981-1984. 

    Fellowship: Pediatric Infectious Diseases, University of Texas Medical School at Houston, Houston, TX, 1987-1990.

    Publications

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    A photo of David Haslam.

    David B. Haslam, MD
    Director, Antimicrobial Stewardship Program

    513-803-1170

    david.haslam@cchmc.org

    David B. Haslam, MD

    Director, Antimicrobial Stewardship Program

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-1170

    Email: david.haslam@cchmc.org

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    Specialties

    Pediatric infectious diseases; host-microbial interactions; innate immunity

    Education and Training

    MD: University of Calgary, Calgary, Alberta, 1987.

    Rotating Internship: McGill University, Montreal, Quebec, 1988.

    Residency: University of Ottawa, Ottawa, Quebec, 1991.

    Fellowship: Washington University School of Medicine, St. Louis, MO, 2005.

    Certification: Pediatric Infectious Diseases, 1997.

    Publications

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    A photo of Margaret Hostetter.

    Margaret K. Hostetter, MD
    Director, Division of Infectious Diseases

    513-636-4509

    margaret.hostetter@cchmc.org

    Margaret K. Hostetter, MD

    Director, Division of Infectious Diseases

    Professor, UC Department of Pediatrics

    Phone: 513-636-4509

    Email: margaret.hostetter@cchmc.org

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    Specialties

    Bacterial and fungal infections; medical evaluation of internationally adopted children

    Education and Training

    MD: Baylor College of Medicine.

    Residency: Boston Children’s Hospital.

    Training Fellowship: Boston Children’s Hospital.

    Board Certification: Pediatrics; Pediatric Infectious Diseases.
    No photo available

    Nancy M. Hutchinson, RN, MSN, CIC
    Nurse Epidemiologist, Infection Control Program

    513-636-8492

    nancy.hutchinson@cchmc.org

    No photo available

    Nancy M. Hutchinson, RN, MSN, CIC

    Nurse Epidemiologist, Infection Control Program

    Field Service Instructor, UC Department of Pediatrics

    Phone: 513-636-8492

    Email: nancy.hutchinson@cchmc.org

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    Education and Training

    RN: Christ Hospital School of Nursing, 1967.

    MSN: University of Cincinnati, 1992.

    Certification: Infection Control Practitioner, CIC, 1995, 2000, 2005.


    No photo available

    Xi Jason Jiang, PhD

    Professor, UC Department of Pediatrics

    Phone: 513-636-0119

    Email: jason.jiang@cchmc.org

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    Specialties

    Infectious diseases; viral gastroenteritis

    Education and Training

    BS: Public Health, Shanghai Medical University, 1978.

    PhD: Baylor College of Medicine, Houston, Texas, 1988.

    Post-doctoral fellow: Baylor College of Medicine, Houston, Texas, 1993.

    Publications

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    Nancy M. Sawtell, PhD

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-7880

    Email: nancy.sawtell@cchmc.org

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    Specialties

    Molecular mechanisms of herpes virus latency and reactivation; viral persistence; pathogenesis; animal models of disease

    Visit the Sawtell Lab.

    Education and Training

    BA: Chemistry, Case Western Reserve University, 1975.

    PhD: Pathology and Immunology, University of Cincinnati Medical College, Cincinnati, OH, 1986.

    Publications

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    A photo of Mary Staat.

    Mary Allen Staat, MD, MPH
    Director, International Adoption Center

    513-636-2877

    mary.staat@cchmc.org

    Mary Staat, MD, MPH

    Director, International Adoption Center

    Professor, UC Department of Pediatrics

    Phone: 513-636-2877

    Fax: 513-636-6936

    Email: mary.staat@cchmc.org

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    Specialties

    Clinical Interests

    Helicobacter pylori, rotavirus epidemiology, travel medicine and infectious diseases of international adoptees

    Research Interests

    Epidemiology of enteric infections and surveillance of infectious diseases

    Biography

    Mary Allen Staat, MD, MPH, is director of the International Adoption Center and a member of the Infectious Disease Division at Cincinnati Children's Hospital Medical Center.

    Dr. Staat is a board-certified pediatrician and is also board-certified in Infectious Disease and Preventive Medicine. She is an associate professor of Pediatrics at the University of Cincinnati and a faculty member of the Cincinnati Children's Hospital Research Foundation.

    Education and Training

    MD: University of Kentucky, Lexington, Ky., 1986.

    MPH: Johns Hopkins University, Baltimore, Md., 1991.

    Residency: Pediatrics, Baylor College of Medicine, Houston, Texas, 1986-1989; Preventive Medicine, Johns Hopkins University, Baltimore, Md., 1990-1994.

    Fellowship: Infectious Diseases, Baylor College of Medicine, Houston, Texas, 1989-1990; Epidemiology, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Rockville, Md., 1990-1993.

    Certification: Pediatrics, 1989; Preventive Medicine, 1996; Pediatric Infectious Diseases, 1999.

    Publications

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    A photo of Mark Steinhoff.

    Mark C. Steinhoff, MD
    Director, Global Health Center

    513-636-1376

    mark.steinhoff@cchmc.org

    Mark C. Steinhoff, MD

    Director, Global Health Center

    Professor, UC Department of Pediatrics

    Phone: 513-636-1376

    Fax: 513-803-0903

    Email: mark.steinhoff@cchmc.org

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    Education and Training

    MD: University of Chicago, Chicago, Illinois, 1973.

    Residency and Chief Residency: Pediatrics, University of Rochester Medical Center, Rochester, New York.

    Fellowship, Infectious Diseases: University of Rochester Medical Center, Rochester, New York.

    Certification: New York State Medical License, 1976; Pediatrics, 1978; Tamil Nadu Medical Council (India), 1980; Michigan Medical License, 1985; Maryland Medical License, 1986; Ohio Medical License, 2010; Pediatric Infectious Diseases Society, 1988.

    Publications

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    Ming Tan, PhD

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-0510

    Email: ming.tan@cchmc.org

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    Specialties

    Noroviruses; human caliciviruses; viral gastroenteritis

    Education and Training

    PhD University of Münster, Münster, Germany, 1997.

    Publications

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    Grants

    Noroviral P particle, a multifunctional platform for vaccine development. Principal Investigator. National Institutes of Health. June 2011 - May 2013.

    Norwalk-like viruses and their receptors. Co-Investigator. National Institutes of Health. Sep 2010 - Apr 2015.

    Novel vaccine against norovirus. Co-Principal Investigator. National Institutes of Health. May 2010 -  Apr 2015.