Nephrology

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    Faculty

    A photo of Prasad Devarajan.

    Prasad Devarajan, MD
    Director, Division of Nephrology and Hypertension

    513-636-4531

    prasad.devarajan@cchmc.org

    Prasad Devarajan, MD

    Director, Division of Nephrology and Hypertension

    Medical Director, Stone Center

    Director, Nephrology and Hypertension Clinical Laboratory

    Louise M. Williams Endowed Chair

    Professor, UC Department of Pediatrics

    Phone: 513-636-4531

    Fax: 513-636-7407

    Email: prasad.devarajan@cchmc.org

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    Specialties

    Clinical specialties: Acute kidney injury, nephrotic syndrome, kidney stones

    Visit the Devarajan Lab.

    Education and Training

    Premedical Studies: Bombay University, India, 1979. 

    MD: Bombay University, India, 1985.

    Publications

    View PubMed Publications
    A photo of Bradley P. Dixon.

    Bradley P. Dixon, MD
    Pediatric Nephrologist

    513-636-4531

    bradley.dixon@cchmc.org

    Bradley P. Dixon, MD

    Pediatric Nephrologist

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4531

    Fax: 513-636-7407

    Email: bradley.dixon@cchmc.org

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    Specialties

    DNA damage response; DNA repair; hyperosmolal microenvironments; atypical hemolytic uremic syndrome; thrombotic microangiopathies; complement-mediated renal diseases.

    Visit the Dixon Lab.

    Biography

    Bradley Dixon, MD, joined the faculty in the Division of Nephrology and Hypertension at Cincinnati Children's in 2006. He has received support for his research from a William Cooper Procter Pediatric Research Award in 2006, a Child Health Research Career Development Award (K12) in 2009, and is currently funded by a K08 through the National Institute of Diabetes, Digestive and Kidney Diseases. Dr. Dixon’s research interests focus on the effects of hyperosmolal microenvironments such as the renal medulla and urinary bladder upon vital cellular processes such as the DNA damage response pathway and activation of cell cycle checkpoints and apoptosis. This research focus attempts to understand the susceptibility of the gastrointestinal tissues used in bladder reconstructions to carcinogenesis.

    In addition to his basic science research interests, Dr. Dixon has a clinical research interest in thrombotic microangiopathies such as atypical hemolytic uremic syndrome (aHUS) and thrombotic thrombocytopenic purpura (TTP), and is an investigator in a number of clinical trials and registries for these diseases. Dr. Dixon is also involved in clinical research studying cystic kidney diseases such as autosomal dominant polycystic kidney disease (ADPKD).

    Education and Training

    BA: College of Wooster, Wooster, OH, 1995.

    MD: University of Tennessee, Memphis, 1999.

    Residency: Cincinnati Children's Hospital Medical Center, 1999-2002.

    Chief Residency: Cincinnati Childrens Hospital, 2002-2003.

    Fellowship: Cincinnati Childrens Hospital, 2003-2006.

    Publications

    View PubMed Publications

    Grants

    DNA Damage and Response in the Bladder Microenvironment. Principal Investigator. National Institutes of Health. Jul 2011 - Apr 2015. #K08 DK081737.

    A photo of Jens W. Goebel.

    Jens W. Goebel, MD
    Clinical Director, Nephrology and Hypertension

    513-636-4531

    jens.goebel@cchmc.org

    Jens W. Goebel, MD

    Clinical Director, Nephrology and Hypertension

    Medical Director, Kidney Transplantation

    Clinical Director, Kidney Transplantation

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4531

    Fax: 513-636-7407

    Email: jens.goebel@cchmc.org

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    Specialties

    Clinical Interests

    Organ transplantation in children

    Research Interests

    Transplant-relevant immunology 

    Biography

    Dr. Goebel was recruited by Cincinnati Children's Hospital Medical Center in 2002 from the University of Kentucky to enhance the institution's kidney transplant program. His efforts along these lines focus both on further improving the clinical care of pediatric kidney transplant recipients and their families, as well as advancing basic and translational investigations into immunological aspects especially relevant to the field of transplantation.

    Education and Training

    MD: University of Heidelberg (Germany), 1991.

    Residency and Chief Residency: Department of Pediatrics, University of South Alabama, Mobile, AL, 1991 to 1995.

    Fellowship: Section of Pediatric Nephrology, Tulane University Medical Center, New Orleans, LA, 1995 to 1998.

    Certifications: General Pediatrics, 1994, 2002; Pediatric Nephrology, 1999.

    Publications

    View PubMed Publications

    Grants

    Center-PI / Co-Investigator / Collaborator:

    NIH UO1 grant: Noninvasive Monitoring to Predict Outcome in de novo Kidney Transplant Recipients (CTOT-01, Protocol Chair: P. Heeger, MD, City), commenced in late 2005 and ongoing

    NIH UO1 grant: Health and Literacy in Child and Adult Assessment: Expanded Testing of the Pediatric PROMIS (Patient Reported Outcomes Measurement Information System) Tool (Sponsor: D. DeWalt, MD, MPH, ), ongoing

    NIH UO1 grant: Chronic Kidney Disease in Children (CKID, PI: B. Warady, MD, Children’s Mercy Hospital, Kansas City, MO), ongoing

    NIH RO1 grant: Calcineurin Inhibitor Minimization And Foxp3+ Tregs Post-Transplant (PIs: Wayne Hancock, MD, Children’s , and John Bucuvalas, MD, Cincinnati Children’s Hospital), ongoing

    Midwest Pediatric Nephrology Consortium: Assessing and Implementing Transition to Adult Care in Children with CKD (PI: M. Ferris, MD, MPH, PhD, ), ongoing

    Amgen Pharmaceuticals: Pediatric Anemia Correction Study (Protocol 20050256), ongoing

    Roche Pharmaceuticals: Development of Population Pharmacokinetic models of Mycophenolic Acid for use in Bayesian Dose Individualization in Pediatric Kidney Transplant Patients (PI: A. Vinks, Cincinnati Children’s Hospital), ongoing

    Cincinnati Children’s Hospital Medical Center Outcomes Research Award: Validation of a Real-Time Adherence Assessment System (PI: A. Pai, PhD, Cincinnati Children’s Hospital), ongoing

    Cincinnati Children’s Hospital Medical Center Translational Research Initiative grant: Pharmacogenetics of Mycophenolic Acid in Kidney Transplant Patients (PI: A. Vinks, Cincinnati Children’s Hospital), ongoing

    Cincinnati Children’s Hospital Medical Center Translational Research Initiative grant: Biomarkers for Patient-tailored Therapies in Pediatric Lupus Nephritis using Mycophenolic Acid (PI: H. Brunner, Cincinnati Children’s Hospital), ongoing

    Cincinnati Children’s Hospital Medical Center Translational Research Initiative grant: Pharmacogenetics of IMPDH in Kidney Transplant Patients (PI: A. Vinks, Cincinnati Children’s Hospital), ongoing

    A photo of Stuart L. Goldstein.

    Stuart L. Goldstein, MD
    Director, Center for Acute Care Nephrology

    513-803-3295

    stuart.goldstein@cchmc.org

    Stuart L. Goldstein, MD

    Director, Center for Acute Care Nephrology

    Professor, UC Department of Pediatrics

    Phone: 513-803-3295

    Fax: 513-636-6407

    Email: stuart.goldstein@cchmc.org

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    Specialties

    Clinical Interests

    Acute kidney injury; continuous renal replacement therapy; end-stage renal disease; health-related quality of life

    Research Interests

    Acute kidney injury epidemiology and biomarkers; health-related quality of life in ESRD; cardiovascular complications and inflammation in ESRD

    Biography

    Stuart L. Goldstein, MD has been an active investigator in the field of pediatric acute kidney injury (AKI) since 2000.  Dr.  Goldstein’s main research foci include: AKI epidemiology and outcomes, acute renal replacement therapy provision and investigation of novel urinary AKI biomarkers in the pediatric population.  Dr. Goldstein has established a strong record of interdisciplinary and inter-institutional collaboration with cardiologists, intensivists and emergency center physicians, which is evidenced by his establishment and directing of the Prospective Pediatric Continuous Renal Replacement Therapy Registry from 2001 to 2012, and the Prospective Pediatric AKI Research Group (ppAKI-RG) in 2012. The ppAKI-RG is comprised of 39 centers from around the world with the goal of improving outcomes for the child with or at-risk for, AKI. 

    Dr. Goldstein has led initial efforts to develop a standardized definition for pediatric AKI, assess novel AKI biomarkers in heterogeneous populations, and conceiving and validating stratification tools to identify patients at risk for AKI.  Building up these findings, Dr. Goldstein embarked on establishing the ppAKI-RG consortium to focus on multi-centered research studies that are dedicated to understanding and treating AKI in pediatric patients.  Currently, the ppAKI-RG has initiated three major, and unprecedented, national and international studies (AWARE, NINJA and DIRECT) to reduce AKI and improve patient outcomes.  Dr. Goldstein is also a recognized educator; he has developed the only pediatric specific Acute Care Nephrology sub-specialty fellowship with graduates who are now leaders in the field of pediatric AKI.

    Education and Training

    MD: Columbia College of Physicians and Surgeons, New York, NY, 1990.

    Residency: Baylor College of Medicine, Houston, TX.

    Fellowship: Pediatric Nephrology, Children's Hospital, Boston, MA.

    Publications

    View PubMed Publications

    Grants

    PlasmaLyte Gastroenteritis Study. Principal Investigator. Baxter Healthcare. Nov 2010 - Oct 2011.

    Inflammation, malnutrition and cardiac calcification in pediatric ESRD patients receiving dialysis- a comparison of hemodialysis vs. peritoneal dialysis. Principal Investigator. Baxter Healthcare. Dec 2010 - Dec 2011.

    Optimize Fluid Dosing in Critically Ill Children with Acute Kidney Injury. Principal Investigator. Casey Lee Ball Foundation. Jan 2011 – Dec 2011.

    Use of NGAL to Optimize Fluid Dosing, CRRT Initiation and Discontinuation in Critically Ill Children with Acute Kidney Injury. Principal Investigator. Casey Lee Ball Foundation. Feb 2011 - Jan 2012.

    Evaluation of cystatin C and Urine Proteins as Early Biomarkers of AKI in Children Treated with Nephrotoxic Medication. Principal Investigator. The Research Institute of McGill University Health Centre. Jun 2011 – Jun 2012.

    Center for Acute Care Nephrology Fellowship. Fellowship Director. Funded by Gambra Renal Products.  Jan 2011 - Jan 2013.

    Inflammation, malnutrition and cardiac calcification in pediatric ESRD patients receiving dialysis. Principal Investigator.  Casey Lee Ball Foundation. Jan 2010 - Dec 2020.


    A photo of Dr. David Hooper.

    David K. Hooper, MD, MS
    Pediatric Nephrologist

    513-636-4531

    david.hooper@cchmc.org

    David K. Hooper, MD, MS

    Pediatric Nephrologist

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4531

    Fax: 513-636-7407

    Email: david.hooper@cchmc.org

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    Specialties

    Nephrology; kidney transplantation; quality improvement

    Biography

    Jointly appointed in the Division of Nephrology and Hypertension and the James M. Anderson Center for Health Systems Excellence at Cincinnati Children’s Hospital, Dr. Hooper's aim is to improve clinical outcomes for pediatric kidney transplant recipients through research in personalized care and the design of reliable healthcare systems.

    Dr. Hooper's research training includes a Masters Degree in clinical and translational research from the University of Cincinnati, in addition to advanced training in quality improvement methodology through the Quality Scholars in Healthcare Transformation program at Cincinnati Children’s Hospital.

    Dr. Hooper's career focus is to combine clinical outcomes research with quality improvement to reliably prevent cardiovascular disease, the leading cause of long-term death and disability in pediatric transplant recipients.

    Education and Training

    MD: University of Utah, Salt Lake City, Utah, 2003.

    Residency: Cincinnati Children's Hospital, Cincinnati, Ohio, 2006.

    Chief Residency: Cincinnati Children's Hospital, Cincinnati, Ohio, 2007.

    MS: University of Cincinnati, Cincinnati, Ohio, 2010.

    Fellowship: Cincinnati Children's Hospital, Cincinnati Ohio, 2010; Quality Scholar in Healthcare Transformation, James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital, Cincinnati, Ohio, 2011.

    Certification: Pediatrics, 2006.

    Publications

    View PubMed Publications

    Grants

    A Reliable System for Blood Pressure Control. Principal Investigator. KL2 Research Scholars (8KL2TR000078-04), Center for Clinical and Translational Science Training, University of Cincinnati. Apr 2012 - Mar 2014.

    A Reliable System for Blood Pressure Control. Principal Investigator. Place Outcomes Research Award. James M. Anderson Center for Health Systems Excellence. Cincinnati Children’s Hospital Medical Center. Jul 2012 - Jun 2014.

    A photo of Elizabeth Jackson.

    Elizabeth C. Jackson, MD
    Director, Healthy Bladder Clinic

    513-636-4975

    elizabeth.jackson@cchmc.org

    Elizabeth C. Jackson, MD

    Director, Healthy Bladder Clinic

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4975

    Fax: 513-636-6753

    Email: elizabeth.jackson@cchmc.org

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    Specialties

    Functional bladder disorders; neurogenic bladder; urolithiasis 

    Biography

    Elizabeth C. Jackson, MD, is a pediatric nephrologist recognized in the need for bladder management. Dr. Jackson has recently discontinued her inpatient nephrology role, and is currently focused on outpatient lower urinary tract management. She is the director of the Healthy Bladder Clinic at Cincinnati Children's. The Healthy Bladder Clinic cares for children with functional lower urinary tract disorders. There are more than 1200 visits per year to this clinic.

    Education and Training

    MD: University of Virginia, Charlottesville, Virginia, 1978.

    Residency: Children's Hospital of Pittsburgh, Pittsburgh, PA, 1981.

    Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 1984.

    Certification: Pediatrics, 1983; Pediatric Nephrology, 1985.

    Publications

    View PubMed Publications

    Grants

    Comparison of voice and buzzer alarms for nocturnal enuresis. Principal Investigator. Cincinnati Children's Hospital Medical Center. Oct 2011 - present.

    A photo of Paul T. McEnery, MD.

    Paul T. McEnery, MD

    Emeritus Professor of Pediatrics

    Phone: 513-636-8652

    Email: paul.mcenery@cchmc.org

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    Specialties

    Glomerulonephritis; vitamin D resistant rickets; care of the child with end-stage renal disease

    Education and Training

    MD: Loyola University, Chicago, IL, 1965. 

    Residency: Children's Hospital Medical Center, Cincinnati, OH.

    Fellowship: Nephrology, Children's Hospital Medical Center, Cincinnati, OH.

    Certification: Pediatrics 1974, 1986, 1993; Pediatric Nephrology, 1974, 1986, 1993.

    MBA: Xavier University, 1989.

    Publications

    View PubMed Publications
    A photo of Mark Mitsnefes.

    Mark M. Mitsnefes, MD, MS
    Director, Clinical and Translational Research Center

    513-636-0125

    mark.mitsnefes@cchmc.org

    Mark M. Mitsnefes, MD, MS

    Director, Clinical and Translational Research Center

    Pediatric Nephrologist

    Professor, UC Department of Pediatrics

    Phone: 513-636-0125

    Fax: 513-636-7407

    Email: mark.mitsnefes@cchmc.org

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    Specialties

    Nephrology with focus on chronic kidney disease and hypertension

    Biography

    Mark Mitsnefes, MD, MS, is an established clinical investigator with expertise in the area of understanding the development of risk factors for cardiovascular disease in children with chronic kidney disease. The long-term goal of his research is to define biologic targets for interventions to prevent and slow progression of cardiovascular disease in children with chronic kidney disease.

    Dr. Misnefes has received numerous awards, including the Proctor Scolar Award (Cincinnati Children's Research Foundation), the Pediatrician Scientist Award (Children's Health Research Center, NIH), the Clinical Scientist Award (National Kidney Foundation), and has been ranked as one of the Best Doctors in America, 2007-2011.

    Education and Training

    MD: Gorky Medical Institute, Gorky, Russia, 1985.

    Residency: Miami Children's Hospital, Miami, Florida, 1997.

    Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2000.

    MS: Epidemiology and Biostatistics, University of Cincinnati, Cincinnati, Ohio, 2001.

    Certifications: Educational Commission for Foreign Medical Graduates (ECFMG), 1995; Pediatrics, 1996; Pediatric Nephrology, 2001, 2008.

    Publications

    View PubMed Publications

    Grants

    Adiponectin and Cardiovascular Disease in the CKiD Children. Principal Investigator. National Institutes of Health. 2007 - 2011. #R01 DK076957.

    Modify Dietary Behavior in Adolescents with Elevated Blood Pressure. Co-investigator. National Institutes of Health. 2007 - 2012.

    Prospective study of chronic kidney disease in children. Co-investigator, Co-chair of the Cardiovascular Committee. National Institutes of Health. 2003 - 2013. #U01 DK-03-012.

    Cardiovascular disease in children with CKD. Principal Investigator. National Institutes of Health. 2011 - 2016. #K24 DK090070-01.


    A photo of Frederic Strife.

    C. Frederic Strife, MD
    Emeritus Professor

    513-636-4531

    fred.strife@cchmc.org

    C. Frederic Strife, MD

    Emeritus Professor

    Director of the Dialysis Unit

    Professor, UC Department of Pediatrics

    Phone: 513-636-4531

    Fax: 513-636-7407

    Email: fred.strife@cchmc.org

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    Specialties

    Glomerulonephritis; renal tubular disorders; growth failure in chronic renal disease; dialysis

    Education and Training

    MD: College of Medicine and Dentistry of New Jersey, 1968.

    Residency: Pediatrics, Children's Hospital Medical Center, Cincinnati, OH.

    Fellowship: Nephrology, Children's Hospital Medical Center, Cincinnati, OH.

    Certification: Pediatrics, 1973; Pediatric Nephrology, 1976.

    Publications

    View PubMed Publications
    A photo of Rene Van de Voorde.

    Rene G. Van De Voorde III, MD
    Medical Director, Dialysis Unit

    513-636-4531

    rene.vandevoorde@cchmc.org

    Rene G. Van De Voorde, MD

    Medical Director, Dialysis Unit

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4531

    Fax: 513-636-7407

    Email: rene.vandevoorde@cchmc.org

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    Specialties

    Dialysis; primarily infant dialysis; chronic kidney disease; acute kidney injury; hypertension

    Education and Training

    MD: Vanderbilt University.

    Residency: Pediatrics, Cincinnati Children's Hospital.

    Chief Resident: Pediatrics, Cincinnati Children's Hospital.

    Fellowship: Pediatric Nephrology, Cincinnati Children's Hospital.

    Certification: Pediatrics, 2003; Pediatric Nephrology, 2008.

    Publications

    View PubMed Publications

    Grants

    Prospective, Multicenter Study to Evaluate the Safety of Vitamin D Receptor Activators as Determined by Hypercalcemia in Pediatric Patients ages 0 to 16 with Chronic Kidney Disease Stage 5 Receiving Peritoneal Dialysis within Current Clinical Practice. Site- Principal Investigator. Jun 2010 - present.

    Randomized, Open-Label, Active-Controlled Study of the Safety, Efficacy, and Pharmacokinetics of Ferumoxytol Compared with Oral Iron for the Treatment of Iron Deficiency Anemia in Pediatric Subjects with Dialysis dependent Chronic Kidney Disease. Site Co-investigator. AMAG Pharmaceutical. Apr 2011 - present.

    Randomized, Open-Label, Active-Controlled Study of the Safety, Efficacy, and Pharmacokinetics of Ferumoxytol Compared with Oral Iron for the Treatment of Iron Deficiency Anemia in Pediatric Subjects with Non-dialysis dependent Chronic Kidney Disease. Site-Principal Investigator. AMAG Pharmaceuticals. Apr 2011 - present.